| Title : Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells - Singha_2020_Eur.J.Pharm.Sci_149_105321 |
| Author(s) : Singha PK , Maklin K , Vihavainen T , Laitinen T , Nevalainen TJ , Patil MR , Tonduru AK , Poso A , Laitinen JT , Savinainen JR |
| Ref : Eur J Pharm Sci , 149 :105321 , 2020 |
| Abstract : |
| PubMedSearch : Singha_2020_Eur.J.Pharm.Sci_149_105321 |
| PubMedID: 32275951 |
| Title : Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha\/beta-hydrolase domain containing 11 (ABHD11) - Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| Author(s) : Navia-Paldanius D , Patel JZ , Lopez Navarro M , Jakupovic H , Goffart S , Pasonen-Seppanen S , Nevalainen TJ , Jaaskelainen T , Laitinen T , Laitinen JT , Savinainen JR |
| Ref : Eur J Pharm Sci , 93 :253 , 2016 |
| Abstract : |
| PubMedSearch : Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| PubMedID: 27544863 |
| Gene_locus related to this paper: human-ABHD11 |
| Title : Comparative molecular field analysis and molecular dynamics studies of alpha\/beta hydrolase domain containing 6 (ABHD6) inhibitors - Kaczor_2015_J.Mol.Model_21_2789 |
| Author(s) : Kaczor AA , Targowska-Duda KM , Patel JZ , Laitinen T , Parkkari T , Adams Y , Nevalainen TJ , Poso A |
| Ref : J Mol Model , 21 :2789 , 2015 |
| Abstract : |
| PubMedSearch : Kaczor_2015_J.Mol.Model_21_2789 |
| PubMedID: 26350245 |
| Title : Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors - Patel_2015_ChemMedChem_10_253 |
| Author(s) : Patel JZ , Nevalainen TJ , Savinainen JR , Adams Y , Laitinen T , Runyon RS , Vaara M , Ahenkorah S , Kaczor AA , Navia-Paldanius D , Gynther M , Aaltonen N , Joharapurkar AA , Jain MR , Haka AS , Maxfield FR , Laitinen JT , Parkkari T |
| Ref : ChemMedChem , 10 :253 , 2015 |
| Abstract : |
| PubMedSearch : Patel_2015_ChemMedChem_10_253 |
| PubMedID: 25504894 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors - Patel_2015_Bioorg.Med.Chem_23_6335 |
| Author(s) : Patel JZ , van Bruchem J , Laitinen T , Kaczor AA , Navia-Paldanius D , Parkkari T , Savinainen JR , Laitinen JT , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry , 23 :6335 , 2015 |
| Abstract : |
| PubMedSearch : Patel_2015_Bioorg.Med.Chem_23_6335 |
| PubMedID: 26344596 |
| Title : Loratadine analogues as MAGL inhibitors - Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| Author(s) : Patel JZ , Ahenkorah S , Vaara M , Staszewski M , Adams Y , Laitinen T , Navia-Paldanius D , Parkkari T , Savinainen JR , Walczynski K , Laitinen JT , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1436 , 2015 |
| Abstract : |
| PubMedSearch : Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| PubMedID: 25752982 |
| Title : Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) - Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| Author(s) : Korhonen J , Kuusisto A , van Bruchem J , Patel JZ , Laitinen T , Navia-Paldanius D , Laitinen JT , Savinainen JR , Parkkari T , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry , 22 :6694 , 2014 |
| Abstract : |
| PubMedSearch : Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| PubMedID: 25282655 |