| Title : In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)m ethanone (JJKK-048) - Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| Author(s) : Aaltonen N , Kedzierska E , Orzelska-Gorka J , Lehtonen M , Navia-Paldanius D , Jakupovic H , Savinainen JR , Nevalainen T , Laitinen JT , Parkkari T , Gynther M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 359 :62 , 2016 |
| Abstract : |
| PubMedSearch : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| PubMedID: 27451409 |
| Title : Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors - Patel_2015_ChemMedChem_10_253 |
| Author(s) : Patel JZ , Nevalainen TJ , Savinainen JR , Adams Y , Laitinen T , Runyon RS , Vaara M , Ahenkorah S , Kaczor AA , Navia-Paldanius D , Gynther M , Aaltonen N , Joharapurkar AA , Jain MR , Haka AS , Maxfield FR , Laitinen JT , Parkkari T |
| Ref : ChemMedChem , 10 :253 , 2015 |
| Abstract : |
| PubMedSearch : Patel_2015_ChemMedChem_10_253 |
| PubMedID: 25504894 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi\/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase - Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| Author(s) : Navia-Paldanius D , Aaltonen N , Lehtonen M , Savinainen JR , Taschler U , Radner FP , Zimmermann R , Laitinen JT |
| Ref : Eur J Pharm Sci , 77 :180 , 2015 |
| Abstract : |
| PubMedSearch : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedID: 26070239 |
| Title : Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice - Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| Author(s) : Aaltonen N , Riera Ribas C , Lehtonen M , Savinainen JR , Laitinen JT |
| Ref : Eur J Pharm Sci , 51 :87 , 2014 |
| Abstract : |
| PubMedSearch : Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| PubMedID: 24012970 |
| Title : Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase - Aaltonen_2013_Chem.Biol_20_379 |
| Author(s) : Aaltonen N , Savinainen JR , Ribas CR , Ronkko J , Kuusisto A , Korhonen J , Navia-Paldanius D , Hayrinen J , Takabe P , Kasnanen H , Pantsar T , Laitinen T , Lehtonen M , Pasonen-Seppanen S , Poso A , Nevalainen T , Laitinen JT |
| Ref : Chemical Biology , 20 :379 , 2013 |
| Abstract : |
| PubMedSearch : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedID: 23521796 |
| Gene_locus related to this paper: human-MGLL |