Full name : Minarini Anna
First name : Anna
Mail : Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126, Bologna
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Country : Italy
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Title : Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties - Basagni_2023_Eur.J.Med.Chem_261_115803 |
Author(s) : Basagni F , Ortega JA , Bertozzi SM , Armirotti A , Summa M , Bertorelli R , Bartolini M , Mellor IR , Bedeschi M , Bottegoni G , Lembo V , Minarini A , Cavalli A , Rosini M |
Ref : Eur Journal of Medicinal Chemistry , 261 :115803 , 2023 |
Abstract : |
PubMedSearch : Basagni_2023_Eur.J.Med.Chem_261_115803 |
PubMedID: 37734258 |
Title : Memantine Derivatives as Multitarget Agents in Alzheimer's Disease - Marotta_2020_Molecules_25_ |
Author(s) : Marotta G , Basagni F , Rosini M , Minarini A |
Ref : Molecules , 25 : , 2020 |
Abstract : |
PubMedSearch : Marotta_2020_Molecules_25_ |
PubMedID: 32887400 |
Title : Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-beta peptide in Alzheimer's disease - Rosini_2019_Eur.J.Med.Chem_180_111 |
Author(s) : Rosini M , Simoni E , Caporaso R , Basagni F , Catanzaro M , Abu IF , Fagiani F , Fusco F , Masuzzo S , Albani D , Lanni C , Mellor IR , Minarini A |
Ref : Eur Journal of Medicinal Chemistry , 180 :111 , 2019 |
Abstract : |
PubMedSearch : Rosini_2019_Eur.J.Med.Chem_180_111 |
PubMedID: 31301562 |
Title : Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-beta aggregation - Simoni_2017_Future.Med.Chem_9_953 |
Author(s) : Simoni E , Bartolini M , Abu IF , Blockley A , Gotti C , Bottegoni G , Caporaso R , Bergamini C , Andrisano V , Cavalli A , Mellor IR , Minarini A , Rosini M |
Ref : Future Med Chem , 9 :953 , 2017 |
Abstract : |
PubMedSearch : Simoni_2017_Future.Med.Chem_9_953 |
PubMedID: 28632446 |
Title : In Vivo Characterization of ARN14140, a Memantine\/Galantamine-Based Multi-Target Compound for Alzheimer's Disease - Reggiani_2016_Sci.Rep_6_33172 |
Author(s) : Reggiani AM , Simoni E , Caporaso R , Meunier J , Keller E , Maurice T , Minarini A , Rosini M , Cavalli A |
Ref : Sci Rep , 6 :33172 , 2016 |
Abstract : |
PubMedSearch : Reggiani_2016_Sci.Rep_6_33172 |
PubMedID: 27609215 |
Title : Multitarget strategies in Alzheimer's disease: benefits and challenges on the road to therapeutics - Rosini_2016_Future.Med.Chem_8_697 |
Author(s) : Rosini M , Simoni E , Caporaso R , Minarini A |
Ref : Future Med Chem , 8 :697 , 2016 |
Abstract : |
PubMedSearch : Rosini_2016_Future.Med.Chem_8_697 |
PubMedID: 27079260 |
Title : Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces - Rosini_2014_Neurochem.Res_39_1914 |
Author(s) : Rosini M , Simoni E , Minarini A , Melchiorre C |
Ref : Neurochem Res , 39 :1914 , 2014 |
Abstract : |
PubMedSearch : Rosini_2014_Neurochem.Res_39_1914 |
PubMedID: 24493627 |
Title : Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment - Minarini_2012_Neuropharmacol_62_997 |
Author(s) : Minarini A , Milelli A , Tumiatti V , Rosini M , Simoni E , Bolognesi ML , Andrisano V , Bartolini M , Motori E , Angeloni C , Hrelia S |
Ref : Neuropharmacology , 62 :997 , 2012 |
Abstract : |
PubMedSearch : Minarini_2012_Neuropharmacol_62_997 |
PubMedID: 22032870 |
Title : Tacrine derivatives and Alzheimer's disease - Tumiatti_2010_Curr.Med.Chem_17_1825 |
Author(s) : Tumiatti V , Minarini A , Bolognesi ML , Milelli A , Rosini M , Melchiorre C |
Ref : Curr Med Chem , 17 :1825 , 2010 |
Abstract : |
PubMedSearch : Tumiatti_2010_Curr.Med.Chem_17_1825 |
PubMedID: 20345341 |
Title : MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond - Bolognesi_2009_Curr.Pharm.Des_15_601 |
Author(s) : Bolognesi ML , Rosini M , Andrisano V , Bartolini M , Minarini A , Tumiatti V , Melchiorre C |
Ref : Curr Pharm Des , 15 :601 , 2009 |
Abstract : |
PubMedSearch : Bolognesi_2009_Curr.Pharm.Des_15_601 |
PubMedID: 19199985 |
Title : From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease - Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
Author(s) : Bolognesi ML , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
Ref : Mini Rev Med Chem , 8 :960 , 2008 |
Abstract : |
PubMedSearch : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
PubMedID: 18782050 |
Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer - Tumiatti_2008_J.Med.Chem_51_7308 |
Author(s) : Tumiatti V , Milelli A , Minarini A , Rosini M , Bolognesi ML , Micco M , Andrisano V , Bartolini M , Mancini F , Recanatini M , Cavalli A , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 51 :7308 , 2008 |
Abstract : |
PubMedSearch : Tumiatti_2008_J.Med.Chem_51_7308 |
PubMedID: 18954037 |
Title : Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush - Rosini_2008_J.Med.Chem_51_4381 |
Author(s) : Rosini M , Simoni E , Bartolini M , Cavalli A , Ceccarini L , Pascu N , McClymont DW , Tarozzi A , Bolognesi ML , Minarini A , Tumiatti V , Andrisano V , Mellor IR , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 51 :4381 , 2008 |
Abstract : |
PubMedSearch : Rosini_2008_J.Med.Chem_51_4381 |
PubMedID: 18605718 |
Title : Rational approach to discover multipotent anti-Alzheimer drugs - Rosini_2005_J.Med.Chem_48_360 |
Author(s) : Rosini M , Andrisano V , Bartolini M , Bolognesi ML , Hrelia P , Minarini A , Tarozzi A , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 48 :360 , 2005 |
Abstract : |
PubMedSearch : Rosini_2005_J.Med.Chem_48_360 |
PubMedID: 15658850 |
Title : Heterocyclic inhibitors of AChE acylation and peripheral sites - Bolognesi_2005_Farmaco_60_465 |
Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Cavalli A , Minarini A , Recanatini M , Rosini M , Tumiatti V , Melchiorre C |
Ref : Farmaco , 60 :465 , 2005 |
Abstract : |
PubMedSearch : Bolognesi_2005_Farmaco_60_465 |
PubMedID: 15878569 |
Title : Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues - Bolognesi_2004_J.Med.Chem_47_5945 |
Author(s) : Bolognesi ML , Bartolini M , Cavalli A , Andrisano V , Rosini M , Minarini A , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 47 :5945 , 2004 |
Abstract : |
PubMedSearch : Bolognesi_2004_J.Med.Chem_47_5945 |
PubMedID: 15537349 |
Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties - Tumiatti_2004_J.Med.Chem_47_6490 |
Author(s) : Tumiatti V , Andrisano V , Banzi R , Bartolini M , Minarini A , Rosini M , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 47 :6490 , 2004 |
Abstract : |
PubMedSearch : Tumiatti_2004_J.Med.Chem_47_6490 |
PubMedID: 15588084 |
Title : Polymethylene tetraamine backbone as template for the development of biologically active polyamines - Melchiorre_2003_Med.Res.Rev_23_200 |
Author(s) : Melchiorre C , Antonello A , Banzi R , Bolognesi ML , Minarini A , Rosini M , Tumiatti V |
Ref : Med Res Rev , 23 :200 , 2003 |
Abstract : |
PubMedSearch : Melchiorre_2003_Med.Res.Rev_23_200 |
PubMedID: 12500289 |
Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine - Tumiatti_2003_J.Med.Chem_46_954 |
Author(s) : Tumiatti V , Rosini M , Bartolini M , Cavalli A , Marucci G , Andrisano V , Angeli P , Banzi R , Minarini A , Recanatini M , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 46 :954 , 2003 |
Abstract : |
PubMedSearch : Tumiatti_2003_J.Med.Chem_46_954 |
PubMedID: 12620072 |
Title : Hexahydrochromeno[4,3-b]pyrrole derivatives as acetylcholinesterase inhibitors - Bolognesi_2001_J.Med.Chem_44_105 |
Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 44 :105 , 2001 |
Abstract : |
PubMedSearch : Bolognesi_2001_J.Med.Chem_44_105 |
PubMedID: 11141093 |
Title : [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors - Tumiatti_2000_Bioorg.Med.Chem_8_681 |
Author(s) : Tumiatti V , Angeli P , Andrisano V , Bolognesi ML , Cavalli A , Marucci G , Minarini A , Recanatini M , Rosini M , Melchiorre C |
Ref : Bioorganic & Medicinal Chemistry , 8 :681 , 2000 |
Abstract : |
PubMedSearch : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
PubMedID: 10819156 |
Title : Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists - Rosini_1999_J.Med.Chem_42_5212 |
Author(s) : Rosini M , Budriesi R , Bixel MG , Bolognesi ML , Chiarini A , Hucho F , Krogsgaard-Larsen P , Mellor IR , Minarini A , Tumiatti V , Usherwood PN , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 42 :5212 , 1999 |
Abstract : |
PubMedSearch : Rosini_1999_J.Med.Chem_42_5212 |
PubMedID: 10602706 |
Title : Universal template approach to drug design: polyamines as selective muscarinic receptor antagonists - Bolognesi_1998_J.Med.Chem_41_4150 |
Author(s) : Bolognesi ML , Minarini A , Budriesi R , Cacciaguerra S , Chiarini A , Spampinato S , Tumiatti V , Melchiorre C |
Ref : Journal of Medicinal Chemistry , 41 :4150 , 1998 |
Abstract : |
PubMedSearch : Bolognesi_1998_J.Med.Chem_41_4150 |
PubMedID: 9767650 |
Title : The design of novel methoctramine-related tetraamines as muscarinic receptor subtype selective antagonists - Melchiorre_1995_Life.Sci_56(11-12)_837 |
Author(s) : Melchiorre C , Minarini A , Budriesi R , Chiarini A , Spampinato S , Tumiatti V |
Ref : Life Sciences , 56(11-12) :837 , 1995 |
Abstract : |
PubMedSearch : Melchiorre_1995_Life.Sci_56(11-12)_837 |
PubMedID: 10188783 |
Title : Polymethylene tetraamines as muscarinic receptor probes - Melchiorre_1989_Trends.Pharmacol.Sci_Suppl_55 |
Author(s) : Melchiorre C , Minarini A , Angeli P , Giardina D , Gulini U , Quaglia W |
Ref : Trends in Pharmacological Sciences , Suppl :55 , 1989 |
Abstract : |
PubMedSearch : Melchiorre_1989_Trends.Pharmacol.Sci_Suppl_55 |
PubMedID: 2694524 |