Title : Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency - Galvani_2022_J.Chem.Inf.Model__ |
Author(s) : Galvani F , Scalvini L , Rivara S , Lodola A , Mor M |
Ref : J Chem Inf Model , : , 2022 |
Abstract : |
PubMedSearch : Galvani_2022_J.Chem.Inf.Model__ |
PubMedID: 35580195 |
Gene_locus related to this paper: human-MGLL |
Title : New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators - Montanari_2021_Molecules_26_3254 |
Author(s) : Montanari S , Allara M , Scalvini L , Kostrzewa M , Belluti F , Gobbi S , Naldi M , Rivara S , Bartolini M , Ligresti A , Bisi A , Rampa A |
Ref : Molecules , 26 :3254 , 2021 |
Abstract : |
PubMedSearch : Montanari_2021_Molecules_26_3254 |
PubMedID: 34071439 |
Title : Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines - Castelli_2020_J.Med.Chem_63_1261 |
Author(s) : Castelli R , Scalvini L , Vacondio F , Lodola A , Anselmi M , Vezzosi S , Carmi C , Bassi M , Ferlenghi F , Rivara S , Moller IR , Rand KD , Daglian J , Wei D , Dotsey EY , Ahmed F , Jung KM , Stella N , Singh S , Mor M , Piomelli D |
Ref : Journal of Medicinal Chemistry , 63 :1261 , 2020 |
Abstract : |
PubMedSearch : Castelli_2020_J.Med.Chem_63_1261 |
PubMedID: 31714779 |
Title : Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents - Montanari_2016_J.Med.Chem_59_6387 |
Author(s) : Montanari S , Scalvini L , Bartolini M , Belluti F , Gobbi S , Andrisano V , Ligresti A , Di Marzo V , Rivara S , Mor M , Bisi A , Rampa A |
Ref : Journal of Medicinal Chemistry , 59 :6387 , 2016 |
Abstract : |
PubMedSearch : Montanari_2016_J.Med.Chem_59_6387 |
PubMedID: 27309570 |
Title : Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL - Scalvini_2016_Sci.Rep_6_31046 |
Author(s) : Scalvini L , Vacondio F , Bassi M , Pala D , Lodola A , Rivara S , Jung KM , Piomelli D , Mor M |
Ref : Sci Rep , 6 :31046 , 2016 |
Abstract : |
PubMedSearch : Scalvini_2016_Sci.Rep_6_31046 |
PubMedID: 27499063 |
Title : Monoglyceride lipase: Structure and inhibitors - Scalvini_2016_Chem.Phys.Lipids_197_13 |
Author(s) : Scalvini L , Piomelli D , Mor M |
Ref : Chemistry & Physic of Lipids , 197 :13 , 2016 |
Abstract : |
PubMedSearch : Scalvini_2016_Chem.Phys.Lipids_197_13 |
PubMedID: 26216043 |