Zemek F

General

Full name : Zemek Filip

First name : Filip

Mail : Faculty of Military Health Sciences, University of Defence, Hradec Kralove

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Country : Czech Republic

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References (13)

Title : Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine - Zemek_2014_Expert.Opin.Drug.Saf_13_759
Author(s) : Zemek F , Drtinova L , Nepovimova E , Sepsova V , Korabecny J , Klimes J , Kuca K
Ref : Expert Opin Drug Safety , 13 :759 , 2014
PubMedID: 24845946

Title : The interaction of quaternary reversible acetylcholinesterase inhibitors with the nicotinic receptor - Sepsova_2014_Physiol.Res_63_771
Author(s) : Sepsova V , Krusek J , Karasova JZ , Zemek F , Musilek K , Kuca K , Soukup O
Ref : Physiol Res , 63 :771 , 2014
PubMedID: 25157661

Title : Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study - Sepsova_2013_Int.J.Mol.Sci_14_16882
Author(s) : Sepsova V , Karasova JZ , Korabecny J , Dolezal R , Zemek F , Bennion BJ , Kuca K
Ref : Int J Mol Sci , 14 :16882 , 2013
PubMedID: 23959117

Title : Intravenous application of HI-6 salts (dichloride and dimethansulphonate) in pigs: comparison with pharmacokinetics profile after intramuscular administration - Karasova_2013_Neuro.Endocrinol.Lett_34_74
Author(s) : Karasova JZ , Zemek F , Kunes M , Kvetina J , Chladek J , Jun D , Bures J , Tacheci I , Kuca K
Ref : Neuro Endocrinol Lett , 34 :74 , 2013
PubMedID: 24362096

Title : Transdermal penetration of the acetylcholinesterase reactivator HI-6 in a rat model - Kracmarova_2013_Mil.Med.Sci.Lett_82_185
Author(s) : Kracmarova A , Bartosova L , Karasova JZ , Zemek F , Bajgar J
Ref : Military Medical Science Letters , 82 :185 , 2013
PubMedID:

Title : Toxicological scoring of Alzheimer's disease drug huperzine in a guinea pig model - Pohanka_2012_Toxicol.Mech.Methods_22_231
Author(s) : Pohanka M , Zemek F , Bandouchova H , Pikula J
Ref : Toxicol Mech Methods , 22 :231 , 2012
PubMedID: 22112162

Title : Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties - Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563
Author(s) : Korabecny J , Musilek K , Zemek F , Horova A , Holas O , Nepovimova E , Opletalova V , Hroudova J , Fisar Z , Jung YS , Kuca K
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :6563 , 2011
PubMedID: 21920739

Title : Oximes as inhibitors of acetylholinesterase - a structure-activity relationship (SAR) study - Sepsova_2011_Mil.Med.Sci.Lett_80_178
Author(s) : Sepsova V , Karasova JZ , Zemek F , Bennion BJ , Kuca K
Ref : Military Medical Science Letters , 80 :178 , 2011
PubMedID:

Title : Method optimization for acetylcholinesterase modulators-albumin interactions - Zemek_2011_Mil.Med.Sci.Lett_80_58
Author(s) : Zemek F , Karasova JZ , Musilek K , Kuca K
Ref : Military Medical Science Letters , 80 :58 , 2011
PubMedID:

Title : Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain - Karasova_2011_J.Pharm.Biomed.Anal_54_1082
Author(s) : Karasova JZ , Zemek F , Bajgar J , Vasatova M , Prochazka P , Novotny L , Kuca K
Ref : J Pharm Biomed Anal , 54 :1082 , 2011
PubMedID: 21146949

Title : Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease - Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093
Author(s) : Korabecny J , Musilek K , Holas O , Binder J , Zemek F , Marek J , Pohanka M , Opletalova V , Dohnal V , Kuca K
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :6093 , 2010
PubMedID: 20817518

Title : Passive diffusion of acetylcholinesterase oxime reactivators through the blood-brain barrier: influence of molecular structure - Karasova_2010_Toxicol.In.Vitro_24_1838
Author(s) : Karasova JZ , Pohanka M , Musilek K , Zemek F , Kuca K
Ref : Toxicol In Vitro , 24 :1838 , 2010
PubMedID: 20546883

Title : Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment - Korabecny_2010_Molecules_15_8804
Author(s) : Korabecny J , Musilek K , Holas O , Nepovimova E , Jun D , Zemek F , Opletalova V , Patocka J , Dohnal V , Nachon F , Hroudova J , Fisar Z , Kuca K
Ref : Molecules , 15 :8804 , 2010
PubMedID: 21127466