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| Title : Discovery of small-molecule enzyme activators by activity-based protein profiling - Kok_2020_Nat.Chem.Biol_16_997 |
| Author(s) : Kok BP , Ghimire S , Kim W , Chatterjee S , Johns T , Kitamura S , Eberhardt J , Ogasawara D , Xu J , Sukiasyan A , Kim SM , Godio C , Bittencourt JM , Cameron M , Galmozzi A , Forli S , Wolan DW , Cravatt BF , Boger DL , Saez E |
| Ref : Nat Chemical Biology , 16 :997 , 2020 |
| Abstract : Kok_2020_Nat.Chem.Biol_16_997 |
| ESTHER : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedSearch : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedID: 32514184 |
| Gene_locus related to this paper: human-LYPLAL1 |
| Title : N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases - Otrubova_2019_Bioorg.Med.Chem_27_1693 |
| Author(s) : Otrubova K , Chatterjee S , Ghimire S , Cravatt BF , Boger DL |
| Ref : Bioorganic & Medicinal Chemistry , 27 :1693 , 2019 |
| Abstract : Otrubova_2019_Bioorg.Med.Chem_27_1693 |
| ESTHER : Otrubova_2019_Bioorg.Med.Chem_27_1693 |
| PubMedSearch : Otrubova_2019_Bioorg.Med.Chem_27_1693 |
| PubMedID: 30879861 |
| Title : Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor - Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
| Author(s) : Kornahrens AF , Cognetta AB, 3rd , Brody DM , Matthews ML , Cravatt BF , Boger DL |
| Ref : Journal of the American Chemical Society , 139 :7052 , 2017 |
| Abstract : Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
| ESTHER : Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
| PubMedSearch : Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
| PubMedID: 28498651 |
| Title : Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis - Zhao_2015_ACS.Chem.Biol_10_364 |
| Author(s) : Zhao N , Darby CM , Small J , Bachovchin DA , Jiang X , Burns-Huang KE , Botella H , Ehrt S , Boger DL , Anderson ED , Cravatt BF , Speers AE , Fernandez-Vega V , Hodder PS , Eberhart C , Rosen H , Spicer TP , Nathan CF |
| Ref : ACS Chemical Biology , 10 :364 , 2015 |
| Abstract : Zhao_2015_ACS.Chem.Biol_10_364 |
| ESTHER : Zhao_2015_ACS.Chem.Biol_10_364 |
| PubMedSearch : Zhao_2015_ACS.Chem.Biol_10_364 |
| PubMedID: 25457457 |
| Title : Comprehensive Analysis of Structure-Activity Relationships of alpha-Ketoheterocycles as sn-1-Diacylglycerol Lipase alpha Inhibitors - Janssen_2015_J.Med.Chem_58_9742 |
| Author(s) : Janssen FJ , Baggelaar MP , Hummel JJ , Overkleeft HS , Cravatt BF , Boger DL , van der Stelt M |
| Ref : Journal of Medicinal Chemistry , 58 :9742 , 2015 |
| Abstract : Janssen_2015_J.Med.Chem_58_9742 |
| ESTHER : Janssen_2015_J.Med.Chem_58_9742 |
| PubMedSearch : Janssen_2015_J.Med.Chem_58_9742 |
| PubMedID: 26584396 |
| Title : Discovery libraries targeting the major enzyme classes: the serine hydrolases - Otrubova_2014_Bioorg.Med.Chem.Lett_24_3807 |
| Author(s) : Otrubova K , Srinivasan V , Boger DL |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :3807 , 2014 |
| Abstract : Otrubova_2014_Bioorg.Med.Chem.Lett_24_3807 |
| ESTHER : Otrubova_2014_Bioorg.Med.Chem.Lett_24_3807 |
| PubMedSearch : Otrubova_2014_Bioorg.Med.Chem.Lett_24_3807 |
| PubMedID: 25037918 |
| Title : Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain - Kinsey_2009_J.Pharmacol.Exp.Ther_330_902 |
| Author(s) : Kinsey SG , Long JZ , O'Neal ST , Abdullah RA , Poklis JL , Boger DL , Cravatt BF , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :902 , 2009 |
| Abstract : Kinsey_2009_J.Pharmacol.Exp.Ther_330_902 |
| ESTHER : Kinsey_2009_J.Pharmacol.Exp.Ther_330_902 |
| PubMedSearch : Kinsey_2009_J.Pharmacol.Exp.Ther_330_902 |
| PubMedID: 19502530 |
| Title : Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase - DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 |
| Author(s) : DeMartino JK , Garfunkle J , Hochstatter DG , Cravatt BF , Boger DL |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5842 , 2008 |
| Abstract : DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 |
| ESTHER : DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 |
| PubMedSearch : DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 |
| PubMedID: 18639454 |
| Title : Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity - Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 |
| Author(s) : Lichtman AH , Leung D , Shelton CC , Saghatelian A , Hardouin C , Boger DL , Cravatt BF |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 311 :441 , 2004 |
| Abstract : Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 |
| ESTHER : Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 |
| PubMedSearch : Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 |
| PubMedID: 15229230 |
| Title : Effective asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI) - Kastrinsky_2004_J.Org.Chem_69_2284 |
| Author(s) : Kastrinsky DB , Boger DL |
| Ref : J Org Chem , 69 :2284 , 2004 |
| Abstract : Kastrinsky_2004_J.Org.Chem_69_2284 |
| ESTHER : Kastrinsky_2004_J.Org.Chem_69_2284 |
| PubMedSearch : Kastrinsky_2004_J.Org.Chem_69_2284 |
| PubMedID: 15049620 |
| Title : Discovering potent and selective reversible inhibitors of enzymes in complex proteomes - Leung_2003_Nat.Biotechnol_21_687 |
| Author(s) : Leung D , Hardouin C , Boger DL , Cravatt BF |
| Ref : Nat Biotechnol , 21 :687 , 2003 |
| Abstract : Leung_2003_Nat.Biotechnol_21_687 |
| ESTHER : Leung_2003_Nat.Biotechnol_21_687 |
| PubMedSearch : Leung_2003_Nat.Biotechnol_21_687 |
| PubMedID: 12740587 |
| Title : Synthesis and evaluation of a series of c3-substituted cbi analogues of cc-1065 and the duocarmycins - Boger_2001_J.Org.Chem_66_5163 |
| Author(s) : Boger DL , Brunette SR , Garbaccio RM |
| Ref : J Org Chem , 66 :5163 , 2001 |
| Abstract : Boger_2001_J.Org.Chem_66_5163 |
| ESTHER : Boger_2001_J.Org.Chem_66_5163 |
| PubMedSearch : Boger_2001_J.Org.Chem_66_5163 |
| PubMedID: 11463270 |
| Title : Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide - Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 |
| Author(s) : Boger DL , Sato H , Lerner AE , Hedrick MP , Fecik RA , Miyauchi H , Wilkie GD , Austin BJ , Patricelli MP , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 97 :5044 , 2000 |
| Abstract : Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 |
| ESTHER : Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 |
| PubMedSearch : Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 |
| PubMedID: 10805767 |