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| Title : A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus - Tse_2023_Sci.Transl.Med_15_eadg5567 |
| Author(s) : Tse LV , Hou YJ , McFadden E , Lee RE , Scobey TD , Leist SR , Martinez DR , Meganck RM , Schafer A , Yount BL , Mascenik T , Powers JM , Randell SH , Zhang Y , Wang L , Mascola J , McLellan JS , Baric RS |
| Ref : Sci Transl Med , 15 :eadg5567 , 2023 |
| Abstract : Tse_2023_Sci.Transl.Med_15_eadg5567 |
| ESTHER : Tse_2023_Sci.Transl.Med_15_eadg5567 |
| PubMedSearch : Tse_2023_Sci.Transl.Med_15_eadg5567 |
| PubMedID: 37756379 |
| Title : Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties - North_2013_Bioorg.Med.Chem_21_2587 |
| Author(s) : North EJ , Scherman MS , Bruhn DF , Scarborough JS , Maddox MM , Jones V , Grzegorzewicz A , Yang L , Hess T , Morisseau C , Jackson M , McNeil MR , Lee RE |
| Ref : Bioorganic & Medicinal Chemistry , 21 :2587 , 2013 |
| Abstract : North_2013_Bioorg.Med.Chem_21_2587 |
| ESTHER : North_2013_Bioorg.Med.Chem_21_2587 |
| PubMedSearch : North_2013_Bioorg.Med.Chem_21_2587 |
| PubMedID: 23498915 |
| Title : Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability - Scherman_2012_Bioorg.Med.Chem_20_3255 |
| Author(s) : Scherman MS , North EJ , Jones V , Hess TN , Grzegorzewicz AE , Kasagami T , Kim IH , Merzlikin O , Lenaerts AJ , Lee RE , Jackson M , Morisseau C , McNeil MR |
| Ref : Bioorganic & Medicinal Chemistry , 20 :3255 , 2012 |
| Abstract : Scherman_2012_Bioorg.Med.Chem_20_3255 |
| ESTHER : Scherman_2012_Bioorg.Med.Chem_20_3255 |
| PubMedSearch : Scherman_2012_Bioorg.Med.Chem_20_3255 |
| PubMedID: 22522007 |
| Title : Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane - Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
| Author(s) : Grzegorzewicz AE , Pham H , Gundi VA , Scherman MS , North EJ , Hess T , Jones V , Gruppo V , Born SE , Kordulakova J , Chavadi SS , Morisseau C , Lenaerts AJ , Lee RE , McNeil MR , Jackson M |
| Ref : Nat Chemical Biology , 8 :334 , 2012 |
| Abstract : Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
| ESTHER : Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
| PubMedSearch : Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
| PubMedID: 22344175 |
| Title : The structure-activity relationship of urea derivatives as anti-tuberculosis agents - Brown_2011_Bioorg.Med.Chem_19_5585 |
| Author(s) : Brown JR , North EJ , Hurdle JG , Morisseau C , Scarborough JS , Sun D , Kordulakova J , Scherman MS , Jones V , Grzegorzewicz A , Crew RM , Jackson M , McNeil MR , Lee RE |
| Ref : Bioorganic & Medicinal Chemistry , 19 :5585 , 2011 |
| Abstract : Brown_2011_Bioorg.Med.Chem_19_5585 |
| ESTHER : Brown_2011_Bioorg.Med.Chem_19_5585 |
| PubMedSearch : Brown_2011_Bioorg.Med.Chem_19_5585 |
| PubMedID: 21840723 |
| Title : Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy - Yoon_2006_Mol.Cancer.Ther_5_1577 |
| Author(s) : Yoon KJ , Qi J , Remack JS , Virga KG , Hatfield MJ , Potter PM , Lee RE , Danks MK |
| Ref : Mol Cancer Ther , 5 :1577 , 2006 |
| Abstract : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| ESTHER : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedSearch : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedID: 16818517 |
| Title : Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity - Wadkins_2004_Mol.Pharmacol_65_1336 |
| Author(s) : Wadkins RM , Hyatt JL , Yoon KJ , Morton CL , Lee RE , Damodaran K , Beroza P , Danks MK , Potter PM |
| Ref : Molecular Pharmacology , 65 :1336 , 2004 |
| Abstract : Wadkins_2004_Mol.Pharmacol_65_1336 |
| ESTHER : Wadkins_2004_Mol.Pharmacol_65_1336 |
| PubMedSearch : Wadkins_2004_Mol.Pharmacol_65_1336 |
| PubMedID: 15155827 |
| Title : Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application - Yoon_2004_Mol.Cancer.Ther_3_903 |
| Author(s) : Yoon KJ , Hyatt JL , Morton CL , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 3 :903 , 2004 |
| Abstract : Yoon_2004_Mol.Cancer.Ther_3_903 |
| ESTHER : Yoon_2004_Mol.Cancer.Ther_3_903 |
| PubMedSearch : Yoon_2004_Mol.Cancer.Ther_3_903 |
| PubMedID: 15299073 |
| Title : Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans - Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345 |
| Author(s) : Stinear TP , Mve-Obiang A , Small PL , Frigui W , Pryor MJ , Brosch R , Jenkin GA , Johnson PD , Davies JK , Lee RE , Adusumilli S , Garnier T , Haydock SF , Leadlay PF , Cole ST |
| Ref : Proc Natl Acad Sci U S A , 101 :1345 , 2004 |
| Abstract : Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345 |
| ESTHER : Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345 |
| PubMedSearch : Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345 |
| PubMedID: 14736915 |
| Title : Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies - Yoon_2003_Mol.Cancer.Ther_2_1171 |
| Author(s) : Yoon KJ , Krull EJ , Morton CL , Bornmann WG , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 2 :1171 , 2003 |
| Abstract : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| ESTHER : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| PubMedSearch : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| PubMedID: 14617791 |
| Title : Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism - Yoon_2003_Bioorg.Med.Chem_11_3237 |
| Author(s) : Yoon KJ , Morton CL , Potter PM , Danks MK , Lee RE |
| Ref : Bioorganic & Medicinal Chemistry , 11 :3237 , 2003 |
| Abstract : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| ESTHER : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| PubMedSearch : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| PubMedID: 12837533 |