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| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : Loos_2023_Biomed.Pharmacother_166_115304 |
| ESTHER : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |
| Title : P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice - Tang_2014_Clin.Cancer.Res_20_3133 |
| Author(s) : Tang SC , Sparidans RW , Cheung KL , Fukami T , Durmus S , Wagenaar E , Yokoi T , van Vlijmen BJ , Beijnen JH , Schinkel AH |
| Ref : Clin Cancer Research , 20 :3133 , 2014 |
| Abstract : Tang_2014_Clin.Cancer.Res_20_3133 |
| ESTHER : Tang_2014_Clin.Cancer.Res_20_3133 |
| PubMedSearch : Tang_2014_Clin.Cancer.Res_20_3133 |
| PubMedID: 24727322 |