Homo sapiens (Human) CGI-67 C9orf77 FAM108B1 protein Abhydrolase domain-containing protein FAM108B1
ABHD17 proteins are protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization (Lin and Conibear 2015). ABHD17A, 17B, and 17C,are identified as the physiological PSD-95 (the most abundant postsynaptic density scaffolding protein) depalmitoylating enzymes in neurones (Yokoi et al.<\/A> || Q8IY03 Q86YB6 1aa diff + GRRPERGSRLVEDSASAAVLSRPLLPGASARAAQVQS in N-term. otthump00000021455 otthump00000021456
Family : ABHD17-depalmitoylase
Block : X
Position in NCBI Life Tree : Homo sapiens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N EMNNLSFSELC CLFCCPPLSG EIASKLAFLP PDPTYTLMCD ESRTRWTLHL SERADWQYSS REKDAIECFM TRTSKGNRIA CMFVRCSPNA KYTLLFSHGN AVDLGQMSSF YIGLGSRINC NIFSYDYSGY GASSGKPTEK NLYADIEAAW LALRTRYGIR PENVIIYGQS IGTVPSVDLA ARYESAAVIL HSPLTSGMRV AFPDTKETYC FDAFPNIDKI SKITSPVLII HGTEDEVIDF SHGLALFERC QRPVEPLWVE GAGHNDVELY GQYLERLKQF VSQELVQKHK EGK
| Title : ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth - Remsberg_2021_Nat.Chem.Biol__ |
| Author(s) : Remsberg JR , Suciu RM , Zambetti NA , Hanigan TW , Firestone AJ , Inguva A , Long A , Ngo N , Lum KM , Henry CL , Richardson SK , Predovic M , Huang B , Dix MM , Howell AR , Niphakis MJ , Shannon K , Cravatt BF |
| Ref : Nat Chemical Biology , : , 2021 |
| Abstract : |
| PubMedSearch : Remsberg_2021_Nat.Chem.Biol__ |
| PubMedID: 33927411 |
| Gene_locus related to this paper: human-ABHD17A , human-ABHD17B , human-ABHD17C |
| Title : Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization - Tortosa_2017_Neuron_94_809 |
| Author(s) : Tortosa E , Adolfs Y , Fukata M , Pasterkamp RJ , Kapitein LC , Hoogenraad CC |
| Ref : Neuron , 94 :809 , 2017 |
| Abstract : |
| PubMedSearch : Tortosa_2017_Neuron_94_809 |
| PubMedID: 28521134 |
| Gene_locus related to this paper: human-ABHD17A , human-ABHD17B , human-ABHD17C |
| Title : Identification of PSD-95 Depalmitoylating Enzymes - Yokoi_2016_J.Neurosci_36_6431 |
| Author(s) : Yokoi N , Fukata Y , Sekiya A , Murakami T , Kobayashi K , Fukata M |
| Ref : Journal of Neuroscience , 36 :6431 , 2016 |
| Abstract : |
| PubMedSearch : Yokoi_2016_J.Neurosci_36_6431 |
| PubMedID: 27307232 |
| Gene_locus related to this paper: human-ABHD17A , human-ABHD17B , human-ABHD17C , rat-ab17c |
| Title : ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization - Lin_2015_Elife_4_ |
| Author(s) : Lin DT , Conibear E |
| Ref : Elife , 4 : , 2015 |
| Abstract : |
| PubMedSearch : Lin_2015_Elife_4_ |
| PubMedID: 26701913 |
| Gene_locus related to this paper: human-ABHD17A , human-ABHD17B , human-ABHD17C |
| Title : Large-scale profiling of protein palmitoylation in mammalian cells - Martin_2009_Nat.Methods_6_135 |
| Author(s) : Martin BR , Cravatt BF |
| Ref : Nat Methods , 6 :135 , 2009 |
| Abstract : |
| PubMedSearch : Martin_2009_Nat.Methods_6_135 |
| PubMedID: 19137006 |
| Gene_locus related to this paper: human-ABHD17A , human-ABHD17B , human-ABHD17C |
| Title : Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics - Lai_2000_Genome.Res_10_703 |
| Author(s) : Lai CH , Chou CY , Ch'ang LY , Liu CS , Lin W |
| Ref : Genome Res , 10 :703 , 2000 |
| Abstract : |
| PubMedSearch : Lai_2000_Genome.Res_10_703 |
| PubMedID: 10810093 |
| Gene_locus related to this paper: human-ABHD5 , human-ABHD17B |