human-PNLIPRP1

Homo sapiens (Human) pancreatic lipase related protein 1

Comment

also clone MGC:12257 BC005233 13528867

Relationship

Family : Pancreatic_lipase

Block : L

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

MLIFWTITLF LLGAAKGKEV CYEDLGCFSD TEPWGGTAIR PLKILPWSPE KIGTRFLLYT NENPNNFQIL LLSDPSTIEA SNFQMDRKTR FIIHGFIDKG DESWVTDMCK KLFEVEEVNC ICVDWKKGSQ ATYTQAANNV RVVGAQVAQM LDILLTEYSY PPSKVHLIGH SLGAHVAGEA GSKTPGLSRI TGLDPVEASF ESTPEEVRLD PSDADFVDVI HTDAAPLIPF LGFGTNQQMG HLDFFPNGGE SMPGCKKNAL SQIVDLDGIW AGTRDFVACN HLRSYKYYLE SILNPDGFAA YPCTSYKSFE SDKCFPCPDQ GCPQMGHYAD KFAGRTSEEQ QKFFLNTGEA SNFARWRYGV SITLSGRTAT GQIKVALFGN KGNTHQYSIF RGILKPGSTH SYEFDAKLDV GTIEKVKFLW NNNVINPTLP KVGATKITVQ KGEEKTVYNF CSEDTVREDT LLTLTPC

References (7)

Title : Increased fat mass and insulin resistance in mice lacking pancreatic lipase-related protein 1 - Ren_2011_J.Nutr.Biochem_22_691
Author(s) : Ren J , Chen Z , Zhang W , Li L , Sun R , Deng C , Fei Z , Sheng Z , Wang L , Sun X , Wang Z , Fei J
Ref : J Nutr Biochem , 22 :691 , 2011
PubMedID: 21115337
Gene_locus related to this paper: human-PNLIPRP1 , mouse-1plrp

Title : The DNA sequence and comparative analysis of human chromosome 10 - Deloukas_2004_Nature_429_375
Author(s) : Deloukas P , Earthrowl ME , Grafham DV , Rubenfield M , French L , Steward CA , Sims SK , Jones MC , Searle S , Scott C , Howe K , Hunt SE , Andrews TD , Gilbert JG , Swarbreck D , Ashurst JL , Taylor A , Battles J , Bird CP , Ainscough R , Almeida JP , Ashwell RI , Ambrose KD , Babbage AK , Bagguley CL , Bailey J , Banerjee R , Bates K , Beasley H , Bray-Allen S , Brown AJ , Brown JY , Burford DC , Burrill W , Burton J , Cahill P , Camire D , Carter NP , Chapman JC , Clark SY , Clarke G , Clee CM , Clegg S , Corby N , Coulson A , Dhami P , Dutta I , Dunn M , Faulkner L , Frankish A , Frankland JA , Garner P , Garnett J , Gribble S , Griffiths C , Grocock R , Gustafson E , Hammond S , Harley JL , Hart E , Heath PD , Ho TP , Hopkins B , Horne J , Howden PJ , Huckle E , Hynds C , Johnson C , Johnson D , Kana A , Kay M , Kimberley AM , Kershaw JK , Kokkinaki M , Laird GK , Lawlor S , Lee HM , Leongamornlert DA , Laird G , Lloyd C , Lloyd DM , Loveland J , Lovell J , Mclaren S , McLay KE , McMurray A , Mashreghi-Mohammadi M , Matthews L , Milne S , Nickerson T , Nguyen M , Overton-Larty E , Palmer SA , Pearce AV , Peck AI , Pelan S , Phillimore B , Porter K , Rice CM , Rogosin A , Ross MT , Sarafidou T , Sehra HK , Shownkeen R , Skuce CD , Smith M , Standring L , Sycamore N , Tester J , Thorpe A , Torcasso W , Tracey A , Tromans A , Tsolas J , Wall M , Walsh J , Wang H , Weinstock K , West AP , Willey DL , Whitehead SL , Wilming L , Wray PW , Young L , Chen Y , Lovering RC , Moschonas NK , Siebert R , Fechtel K , Bentley D , Durbin R , Hubbard T , Doucette-Stamm L , Beck S , Smith DR , Rogers J
Ref : Nature , 429 :375 , 2004
PubMedID: 15164054
Gene_locus related to this paper: human-LIPA , human-LIPK , human-PNLIPRP1 , human-PNLIPRP2 , human-PNLIPRP3

Title : Pancreatic lipase-related protein type I: a specialized lipase or an inactive enzyme - Crenon_1998_Protein.Eng_11_135
Author(s) : Crenon I , Foglizzo E , Kerfelec B , Verine A , Pignol D , Hermoso J , Bonicel J , Chapus C
Ref : Protein Engineering , 11 :135 , 1998
PubMedID: 9605548
Gene_locus related to this paper: human-PNLIPRP1

Title : Pancreatic lipase-related protein type 1: a double mutation restores a significant lipase activity - Crenon_1998_Biochem.Biophys.Res.Commun_246_513
Author(s) : Crenon I , Jayne S , Kerfelec B , Hermoso J , Pignol D , Chapus C
Ref : Biochemical & Biophysical Research Communications , 246 :513 , 1998
PubMedID: 9610393
Gene_locus related to this paper: human-PNLIPRP1

Title : Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species - De Caro_1998_Biochim.Biophys.Acta_1387_331
Author(s) : De Caro J , Carriere F , Barboni P , Giller T , Verger R , de Caro A
Ref : Biochimica & Biophysica Acta , 1387 :331 , 1998
PubMedID: 9748646
Gene_locus related to this paper: canfa-1plip , human-PNLIPRP1 , ratno-3plip , pig-b8xy18

Title : Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity - Giller_1992_J.Biol.Chem_267_16509
Author(s) : Giller T , Buchwald P , Blum-Kaelin D , Hunziker W
Ref : Journal of Biological Chemistry , 267 :16509 , 1992
PubMedID: 1379598
Gene_locus related to this paper: human-LPL , human-PNLIPRP1 , human-PNLIPRP2

Title : Congenital pancreatic lipase deficiency - Figarella_1980_J.Pediatr_96_412
Author(s) : Figarella C , de Caro A , Leupold D , Poley JR
Ref : J Pediatr , 96 :412 , 1980
PubMedID: 6153713
Gene_locus related to this paper: human-PNLIP , human-PNLIPRP1