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lepin-LA3998

Leptospira interrogans cholesterol oxidase (EC 1.1.3.6)

Comment

only the 300 last aa homologous Pfam A Abhydrolase_6 827 1114. Caution weak similarity not homologous in the Serine region || serogroup icterohaemorrhagiae \/ serova Copenhageni Nascimento et al

Relationship

Family : 6_AlphaBeta_hydrolase

Block : X

Position in NCBI Life Tree : Leptospira interrogans

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Spirochaetes N E > Spirochaetia N E > Leptospirales N E > Leptospiraceae N E > Leptospira N E > Leptospira interrogans N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

GVSSLIFSID TIDTNLLEYL FENQYDVWLF DYRTSIALPS APLPNTGDAI ATKDYPAAVN KVRELTKVDK IQVVAHCFGA TTFTMALLSG LEGVRSVVLS QISADVEVPT SMDIKVGFHT AEILDALGIK DMTAYTSNHD DWLDRFFNSV LALQPQSLFS HDVNPVSRRI SFLYGSLYIL ENLNEETYRY GLGEMFGVSN IKAFEHLSKM IRAHKVVNSE GQDVYVPHLD RLNLPITFIH GAQNRCYLPE STETTYKKLI DRFNPNQYRR HVIPDYGHID CIFGKDAYKD VYPFILQSLN RY

References (2)

Title : Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis - Nascimento_2004_J.Bacteriol_186_2164
Author(s) : Nascimento AL , Ko AI , Martins EA , Monteiro-Vitorello CB , Ho PL , Haake DA , Verjovski-Almeida S , Hartskeerl RA , Marques MV , Oliveira MC , Menck CF , Leite LC , Carrer H , Coutinho LL , Degrave WM , Dellagostin OA , El-Dorry H , Ferro ES , Ferro MI , Furlan LR , Gamberini M , Giglioti EA , Goes-Neto A , Goldman GH , Goldman MH , Harakava R , Jeronimo SM , Junqueira-de-Azevedo IL , Kimura ET , Kuramae EE , Lemos EG , Lemos MV , Marino CL , Nunes LR , de Oliveira RC , Pereira GG , Reis MS , Schriefer A , Siqueira WJ , Sommer P , Tsai SM , Simpson AJ , Ferro JA , Camargo LE , Kitajima JP , Setubal JC , Van Sluys MA
Ref : Journal of Bacteriology , 186 :2164 , 2004
Abstract :
PubMedSearch : Nascimento_2004_J.Bacteriol_186_2164
PubMedID: 15028702
Gene_locus related to this paper: lepin-AXEA , lepin-ESTA , lepin-LA0357 , lepin-LA0587 , lepin-LA0932 , lepin-LA1069 , lepin-LA1345 , lepin-LA1541 , lepin-LA1861 , lepin-LA1902 , lepin-LA1936 , lepin-LA1955 , lepin-LA2034 , lepin-LA2132 , lepin-LA2501 , lepin-LA2505 , lepin-LA2526 , lepin-LA2544 , lepin-LA2857 , lepin-LA2958 , lepin-LA3100 , lepin-LA3107 , lepin-LA3147 , lepin-LA3604 , lepin-LA3661 , lepin-LA3672 , lepin-LA3788 , lepin-LA3851 , lepin-LA3897 , lepin-LA3998 , lepin-METX , lepin-q8f7a8 , lepin-q72tt9

Title : Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing - Ren_2003_Nature_422_888
Author(s) : Ren SX , Fu G , Jiang XG , Zeng R , Miao YG , Xu H , Zhang YX , Xiong H , Lu G , Lu LF , Jiang HQ , Jia J , Tu YF , Jiang JX , Gu WY , Zhang YQ , Cai Z , Sheng HH , Yin HF , Zhang Y , Zhu GF , Wan M , Huang HL , Qian Z , Wang SY , Ma W , Yao ZJ , Shen Y , Qiang BQ , Xia QC , Guo XK , Danchin A , Saint Girons I , Somerville RL , Wen YM , Shi MH , Chen Z , Xu JG , Zhao GP
Ref : Nature , 422 :888 , 2003
Abstract :
PubMedSearch : Ren_2003_Nature_422_888
PubMedID: 12712204
Gene_locus related to this paper: lepin-AXEA , lepin-ESTA , lepin-LA0357 , lepin-LA0587 , lepin-LA0823 , lepin-LA0932 , lepin-LA1069 , lepin-LA1345 , lepin-LA1541 , lepin-LA1702 , lepin-LA1861 , lepin-LA1902 , lepin-LA1936 , lepin-LA1955 , lepin-LA2034 , lepin-LA2132 , lepin-LA2501 , lepin-LA2505 , lepin-LA2526 , lepin-LA2544 , lepin-LA2857 , lepin-LA2958 , lepin-LA3100 , lepin-LA3107 , lepin-LA3147 , lepin-LA3604 , lepin-LA3661 , lepin-LA3669 , lepin-LA3672 , lepin-LA3770 , lepin-LA3788 , lepin-LA3851 , lepin-LA3897 , lepin-LA3998 , lepin-LA4247 , lepin-LB147 , lepin-LB264 , lepin-LB265 , lepin-METX , lepin-q8f7a8 , lepin-q72tt9