rhosm-cocE
Rhodococcus sp. (strain MB1 Bresler) cocaine esterase (EC 3.1.1.-)
Comment
Relationship
Family : Cocaine_esterase
Block : X
Position in NCBI Life Tree : Rhodococcus sp.
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Nocardiaceae N E > Rhodococcus N E > Rhodococcus sp. N EMolecular evidence
Sequence
Peptide
MVDGNYSVAS NVMVPMRDGV RLAVDLYRPD ADGPVPVLLV RNPYDKFDVF AWSTQSTNWL EFVRDGYAVV IQDTRGLFAS EGEFVPHVDD EADAEDTLSW ILEQAWCDGN VGMFGVSYLG VTQWQAAVSG VGGLKAIAPS MASADLYRAP WYGPGGALSV EALLGWSALI GTGLITSRSD ARPEDAADFV QLAAILNDVA GAASVTPLAE QPLLGRLIPW VIDQVVDHPD NDESWQSISL FERLGGLATP ALITAGWYDG FVGESLRTFV AVKDNADARL VVGPWSHSNL TGRNADRKFG IAATYPIQEA TTMHKAFFDR HLRGETDALA GVPKVRLFVM GIDEWRDETD WPLPDTAYTP FYLGGSGAAN TSTGGGTLST SISGTESADT YLYDPADPVP SLGGTLLFHN GDNGPADQRP IHDRDDVLCY STEVLTDPVE VTGTVSARLF VSSSAVDTDF TAKLVDVFPD GRAIALCDGI VRMRYRETLV NPTLIEAGEI YEVAIDMLAT SNVFLPGHRI MVQVSSSNFP KYDRNSNTGG VIAREQLEEM CTAVNRIHRG PEHPSHIVLP IIKR
References (9)
| Title : Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase - Chen_2021_Angew.Chem.Int.Ed.Engl_60_21959 |
| Author(s) : Chen X , Deng X , Zhang Y , Wu Y , Yang K , Li Q , Wang J , Yao W , Tong J , Xie T , Hou S , Yao J |
| Ref : Angew Chem Int Ed Engl , 60 :21959 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Angew.Chem.Int.Ed.Engl_60_21959 |
| PubMedID: 34351032 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Computational design of cephradine synthase in a new scaffold identified from structural databases - Huang_2017_Chem.Commun.(Camb)_53_7604 |
| Author(s) : Huang X , Xue J , Zhu Y |
| Ref : Chem Commun (Camb) , 53 :7604 , 2017 |
| Abstract : |
| PubMedSearch : Huang_2017_Chem.Commun.(Camb)_53_7604 |
| PubMedID: 28639649 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification - Fang_2014_ACS.Chem.Biol_9_1764 |
| Author(s) : Fang L , Chow KM , Hou S , Xue L , Chen X , Rodgers DW , Zheng F , Zhan CG |
| Ref : ACS Chemical Biology , 9 :1764 , 2014 |
| Abstract : |
| PubMedSearch : Fang_2014_ACS.Chem.Biol_9_1764 |
| PubMedID: 24919140 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time - Narasimhan_2011_Mol.Pharmacol_80_1056 |
| Author(s) : Narasimhan D , Collins GT , Nance MR , Nichols J , Edwald E , Chan J , Ko MC , Woods JH , Tesmer JJ , Sunahara RK |
| Ref : Molecular Pharmacology , 80 :1056 , 2011 |
| Abstract : |
| PubMedSearch : Narasimhan_2011_Mol.Pharmacol_80_1056 |
| PubMedID: 21890748 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Structural analysis of thermostabilizing mutations of cocaine esterase - Narasimhan_2010_Protein.Eng.Des.Sel_23_537 |
| Author(s) : Narasimhan D , Nance MR , Gao D , Ko MC , MacDonald J , Tamburi P , Yoon D , Landry DM , Woods JH , Zhan CG , Tesmer JJ , Sunahara RK |
| Ref : Protein Engineering Des Sel , 23 :537 , 2010 |
| Abstract : |
| PubMedSearch : Narasimhan_2010_Protein.Eng.Des.Sel_23_537 |
| PubMedID: 20436035 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse - Brim_2010_Mol.Pharmacol_77_593 |
| Author(s) : Brim RL , Nance MR , Youngstrom DW , Narasimhan D , Zhan CG , Tesmer JJ , Sunahara RK , Woods JH |
| Ref : Molecular Pharmacology , 77 :593 , 2010 |
| Abstract : |
| PubMedSearch : Brim_2010_Mol.Pharmacol_77_593 |
| PubMedID: 20086035 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Biochemical characterization and structural analysis of a highly proficient cocaine esterase - Turner_2002_Biochemistry_41_12297 |
| Author(s) : Turner JM , Larsen NA , Basran A , Barbas CF, 3rd , Bruce NC , Wilson IA , Lerner RA |
| Ref : Biochemistry , 41 :12297 , 2002 |
| Abstract : |
| PubMedSearch : Turner_2002_Biochemistry_41_12297 |
| PubMedID: 12369817 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1 - Bresler_2000_Appl.Environ.Microbiol_66_904 |
| Author(s) : Bresler MM , Rosser SJ , Basran A , Bruce NC |
| Ref : Applied Environmental Microbiology , 66 :904 , 2000 |
| Abstract : |
| PubMedSearch : Bresler_2000_Appl.Environ.Microbiol_66_904 |
| PubMedID: 10698749 |
| Gene_locus related to this paper: rhosm-cocE |