| Title : Discovery of a novel homocysteine thiolactone hydrolase and the catalytic activity of its natural variants - Hou_2024_Protein.Sci_33_e5098 |
| Author(s) : Hou S , Liu H , Hu Y , Zhang J , Deng X , Li Z , Zhang Y , Li X , Li Y , Ma L , Yao J , Chen X |
| Ref : Protein Science , 33 :e5098 , 2024 |
| Abstract : |
| PubMedSearch : Hou_2024_Protein.Sci_33_e5098 |
| PubMedID: 38980003 |
| Title : Catalytic mechanism, computational design, and crystal structure of a highly specific and efficient benzoylecgonine hydrolase - Chen_2024_Int.J.Biol.Macromol__137767 |
| Author(s) : Chen X , Zhang Y , Tong J , Ouyang P , Deng X , Zhang J , Liu H , Hu Y , Yao W , Wang J , Wang X , Hou S , Yao J |
| Ref : Int J Biol Macromol , :137767 , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_Int.J.Biol.Macromol__137767 |
| PubMedID: 39561846 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Assessing the effects of HMGCR, LPL, and PCSK9 inhibition on sleep apnea: Mendelian randomization analysis of drug targets - Tan_2024_Medicine.(Baltimore)_103_e40194 |
| Author(s) : Tan W , Deng X , Tan X , Tan G |
| Ref : Medicine (Baltimore) , 103 :e40194 , 2024 |
| Abstract : |
| PubMedSearch : Tan_2024_Medicine.(Baltimore)_103_e40194 |
| PubMedID: 39470521 |
| Title : UHPLC-Q\/Orbitrap HRMS combined with spectrum-effect relationship and network pharmacology to discovery the gastrointestinal motility-promoting material basis in Citri Sarcodactylis Fructus - Liu_2024_J.Ethnopharmacol_337_118926 |
| Author(s) : Liu X , Gong Q , Deng X , Li L , Luo R , Li X , Guo D , Deng F |
| Ref : J Ethnopharmacol , 337 :118926 , 2024 |
| Abstract : |
| PubMedSearch : Liu_2024_J.Ethnopharmacol_337_118926 |
| PubMedID: 39393559 |
| Title : Fotagliptin monotherapy with alogliptin as an active comparator in patients with uncontrolled type 2 diabetes mellitus: a randomized, multicenter, double-blind, placebo-controlled, phase 3 trial - Xu_2023_BMC.Med_21_388 |
| Author(s) : Xu M , Sun K , Xu W , Wang C , Yan D , Li S , Cong L , Pi Y , Song W , Sun Q , Xiao R , Peng W , Wang J , Peng H , Zhang Y , Duan P , Zhang M , Liu J , Huang Q , Li X , Bao Y , Zeng T , Wang K , Qin L , Wu C , Deng C , Huang C , Yan S , Zhang W , Li M , Sun L , Wang Y , Li H , Wang G , Pang S , Zheng X , Wang H , Wang F , Su X , Ma Y , Li Z , Xie Z , Xu N , Ni L , Zhang L , Deng X , Pan T , Dong Q , Wu X , Shen X , Zhang X , Zou Q , Jiang C , Xi J , Ma J , Sun J , Yan L |
| Ref : BMC Med , 21 :388 , 2023 |
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| PubMedSearch : Xu_2023_BMC.Med_21_388 |
| PubMedID: 37814306 |
| Title : Development of Long-Acting Dipeptidyl Peptidase-4 Inhibitors: Structural Evolution and Long-Acting Determinants - Li_2023_J.Med.Chem__ |
| Author(s) : Li Q , Deng X , Xu YJ , Dong L |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Li_2023_J.Med.Chem__ |
| PubMedID: 37647598 |
| Title : Integrated Proteomic and Metabolomic Analyses of Chicken Ovary Revealed the Crucial Role of Lipoprotein Lipase on Lipid Metabolism and Steroidogenesis During Sexual Maturity - Cui_2022_Front.Physiol_13_885030 |
| Author(s) : Cui Z , Ning Z , Deng X , Du X , Amevor FK , Liu L , Kang X , Tian Y , Wang Y , Li D , Zhao X |
| Ref : Front Physiol , 13 :885030 , 2022 |
| Abstract : |
| PubMedSearch : Cui_2022_Front.Physiol_13_885030 |
| PubMedID: 35574488 |
| Title : [(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models - Shao_2022_Acta.Pharm.Sin.B_12_308 |
| Author(s) : Shao T , Chen Z , Rong J , Belov V , Chen J , Jeyarajan A , Deng X , Fu H , Yu Q , Rwema SH , Lin W , Papisov M , Josephson L , Chung RT , Liang SH |
| Ref : Acta Pharm Sin B , 12 :308 , 2022 |
| Abstract : |
| PubMedSearch : Shao_2022_Acta.Pharm.Sin.B_12_308 |
| PubMedID: 35127387 |
| Title : The Use of Lipoprotein-Associated Phospholipase A2 in a Chinese Population to Predict Cardiovascular Events - Xi_2022_Biomed.Environ.Sci_35_206 |
| Author(s) : Xi H , Cheng GL , Hu FF , Li SN , Deng X , Zhou Y |
| Ref : Biomedical & Environmental Sciences , 35 :206 , 2022 |
| Abstract : |
| PubMedSearch : Xi_2022_Biomed.Environ.Sci_35_206 |
| PubMedID: 35317900 |
| Title : Expression, characterization, and immobilization of a novel SGNH esterase Est882 and its potential for pyrethroid degradation - Zong_2022_Front.Microbiol_13_1069754 |
| Author(s) : Zong W , Su W , Xie Q , Gu Q , Deng X , Ren Y , Li H |
| Ref : Front Microbiol , 13 :1069754 , 2022 |
| Abstract : |
| PubMedSearch : Zong_2022_Front.Microbiol_13_1069754 |
| PubMedID: 36620037 |
| Title : The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial - Liu_2022_BMC.Anesthesiol_22_267 |
| Author(s) : Liu F , Lin X , Lin Y , Deng X , Guo Y , Wang B , Dong R , Bi Y |
| Ref : BMC Anesthesiol , 22 :267 , 2022 |
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| PubMedSearch : Liu_2022_BMC.Anesthesiol_22_267 |
| PubMedID: 35996073 |
| Title : An ultrahigh-throughput screening platform based on flow cytometric droplet sorting for mining novel enzymes from metagenomic libraries - Ma_2021_Environ.Microbiol_23_996 |
| Author(s) : Ma F , Guo T , Zhang Y , Bai X , Li C , Lu Z , Deng X , Li D , Kurabayashi K , Yang GY |
| Ref : Environ Microbiol , 23 :996 , 2021 |
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| Title : ANGPTL8 in metabolic homeostasis: more friend than foe? - Guo_2021_Open.Biol_11_210106 |
| Author(s) : Guo C , Wang C , Deng X , He J , Yang L , Yuan G |
| Ref : Open Biol , 11 :210106 , 2021 |
| Abstract : |
| PubMedSearch : Guo_2021_Open.Biol_11_210106 |
| PubMedID: 34582711 |
| Title : Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase - Chen_2021_Angew.Chem.Int.Ed.Engl_60_21959 |
| Author(s) : Chen X , Deng X , Zhang Y , Wu Y , Yang K , Li Q , Wang J , Yao W , Tong J , Xie T , Hou S , Yao J |
| Ref : Angew Chem Int Ed Engl , 60 :21959 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Angew.Chem.Int.Ed.Engl_60_21959 |
| PubMedID: 34351032 |
| Gene_locus related to this paper: rhosm-cocE |
| Title : Identification and structure-activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus - Li_2021_Eur.J.Med.Chem_225_113765 |
| Author(s) : Li Q , Deng X , Jiang N , Meng L , Xing J , Jiang W , Xu Y |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113765 , 2021 |
| Abstract : |
| PubMedSearch : Li_2021_Eur.J.Med.Chem_225_113765 |
| PubMedID: 34399391 |
| Title : Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors - Shen_2020_Eur.J.Med.Chem_208_112850 |
| Author(s) : Shen J , Deng X , Sun R , Tavallaie MS , Wang J , Cai Q , Lam C , Lei S , Fu L , Jiang F |
| Ref : Eur Journal of Medicinal Chemistry , 208 :112850 , 2020 |
| Abstract : |
| PubMedSearch : Shen_2020_Eur.J.Med.Chem_208_112850 |
| PubMedID: 32987315 |
| Title : Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors - Huang_2019_Bioorg.Med.Chem_27_644 |
| Author(s) : Huang J , Deng X , Zhou S , Wang N , Qin Y , Meng L , Li G , Xiong Y , Fan Y , Guo L , Lan D , Xing J , Jiang W , Li Q |
| Ref : Bioorganic & Medicinal Chemistry , 27 :644 , 2019 |
| Abstract : |
| PubMedSearch : Huang_2019_Bioorg.Med.Chem_27_644 |
| PubMedID: 30642693 |
| Title : Optimization of the benzamide fragment targeting the S2' site leads to potent dipeptidyl peptidase-IV inhibitors - Deng_2019_Bioorg.Chem__103366 |
| Author(s) : Deng X , Wang N , Meng L , Zhou S , Huang J , Xing J , He L , Jiang W , Li Q |
| Ref : Bioorg Chem , :103366 , 2019 |
| Abstract : |
| PubMedSearch : Deng_2019_Bioorg.Chem__103366 |
| PubMedID: 31640932 |
| Title : Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes - Chen_2019_J.Med.Chem_62_8866 |
| Author(s) : Chen Z , Mori W , Fu H , Schafroth MA , Hatori A , Shao T , Zhang G , Van RS , Zhang Y , Hu K , Fujinaga M , Wang L , Belov V , Ogasawara D , Giffenig P , Deng X , Rong J , Yu Q , Zhang X , Papisov MI , Shao Y , Collier TL , Ma JA , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :8866 , 2019 |
| Abstract : |
| PubMedSearch : Chen_2019_J.Med.Chem_62_8866 |
| PubMedID: 31518130 |
| Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
| Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
| Abstract : |
| PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
| PubMedID: 30829483 |
| Gene_locus related to this paper: human-MGLL |
| Title : Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors - Deng_2018_Bioorg.Med.Chem_26_903 |
| Author(s) : Deng X , Shen J , Zhu H , Xiao J , Sun R , Xie F , Lam C , Wang J , Qiao Y , Tavallaie MS , Hu Y , Du Y , Li J , Fu L , Jiang F |
| Ref : Bioorganic & Medicinal Chemistry , 26 :903 , 2018 |
| Abstract : |
| PubMedSearch : Deng_2018_Bioorg.Med.Chem_26_903 |
| PubMedID: 29373269 |
| Title : Discovery of triazole-based uracil derivatives bearing amide moieties as novel dipeptidyl peptidase-IV inhibitors - Deng_2017_Bioorg.Chem_75_357 |
| Author(s) : Deng X , Han L , Zhou J , Zhang H , Li Q |
| Ref : Bioorg Chem , 75 :357 , 2017 |
| Abstract : |
| PubMedSearch : Deng_2017_Bioorg.Chem_75_357 |
| PubMedID: 29096096 |
| Title : Highly Efficient Enzymatic Acylation of Dihydromyricetin by the Immobilized Lipase with Deep Eutectic Solvents as Cosolvent - Cao_2017_J.Agric.Food.Chem_65_2084 |
| Author(s) : Cao SL , Deng X , Xu P , Huang ZX , Zhou J , Li XH , Zong MH , Lou WY |
| Ref : Journal of Agricultural and Food Chemistry , 65 :2084 , 2017 |
| Abstract : |
| PubMedSearch : Cao_2017_J.Agric.Food.Chem_65_2084 |
| PubMedID: 28244316 |
| Title : Genetic analysis of the RIC3 gene in Han Chinese patients with Parkinson's disease - He_2017_Neurosci.Lett_653_351 |
| Author(s) : He D , Hu P , Deng X , Song Z , Yuan L , Yuan X , Deng H |
| Ref : Neuroscience Letters , 653 :351 , 2017 |
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| PubMedSearch : He_2017_Neurosci.Lett_653_351 |
| PubMedID: 28606768 |
| Title : Synthesis of furo[3,2-c]coumarin derivatives using visible-light-promoted radical alkyne insertion with bromocoumarins - Zhou_2016_Org.Biomol.Chem_14_6065 |
| Author(s) : Zhou H , Deng X , Ma Z , Zhang A , Qin Q , Tan RX , Yu S |
| Ref : Org Biomol Chem , 14 :6065 , 2016 |
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| PubMedSearch : Zhou_2016_Org.Biomol.Chem_14_6065 |
| PubMedID: 27241337 |
| Title : Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts - Ma_2016_Nat.Commun_7_10740 |
| Author(s) : Ma L , Chen Z , Huang da W , Kutty G , Ishihara M , Wang H , Abouelleil A , Bishop L , Davey E , Deng R , Deng X , Fan L , Fantoni G , FitzGerald M , Gogineni E , Goldberg JM , Handley G , Hu X , Huber C , Jiao X , Jones K , Levin JZ , Liu Y , Macdonald P , Melnikov A , Raley C , Sassi M , Sherman BT , Song X , Sykes S , Tran B , Walsh L , Xia Y , Yang J , Young S , Zeng Q , Zheng X , Stephens R , Nusbaum C , Birren BW , Azadi P , Lempicki RA , Cuomo CA , Kovacs JA |
| Ref : Nat Commun , 7 :10740 , 2016 |
| Abstract : |
| PubMedSearch : Ma_2016_Nat.Commun_7_10740 |
| PubMedID: 26899007 |
| Gene_locus related to this paper: pnec8-a0a0w4zi95 , pnemu-m7nra0 , pnej8-l0pgn2 , pnemu-m7nsb0 |
| Title : Expression, Purification and Characterisation of Secreted Esterase Rv2525c from Mycobacterium tuberculosis - Dang_2015_Appl.Biochem.Biotechnol_176_1 |
| Author(s) : Dang G , Chen L , Li Z , Deng X , Cui Y , Cao J , Yu S , Pang H , Liu S |
| Ref : Appl Biochem Biotechnol , 176 :1 , 2015 |
| Abstract : |
| PubMedSearch : Dang_2015_Appl.Biochem.Biotechnol_176_1 |
| PubMedID: 25869294 |
| Title : The resurrection genome of Boea hygrometrica: A blueprint for survival of dehydration - Xiao_2015_Proc.Natl.Acad.Sci.U.S.A_112_5833 |
| Author(s) : Xiao L , Yang G , Zhang L , Yang X , Zhao S , Ji Z , Zhou Q , Hu M , Wang Y , Chen M , Xu Y , Jin H , Xiao X , Hu G , Bao F , Hu Y , Wan P , Li L , Deng X , Kuang T , Xiang C , Zhu JK , Oliver MJ , He Y |
| Ref : Proc Natl Acad Sci U S A , 112 :5833 , 2015 |
| Abstract : |
| PubMedSearch : Xiao_2015_Proc.Natl.Acad.Sci.U.S.A_112_5833 |
| PubMedID: 25902549 |
| Gene_locus related to this paper: 9lami-a0a2z7c6k4 , 9lami-a0a2z7bgj4 |
| Title : Complete genome sequencing and comparative analysis of the linezolid-resistant Enterococcus faecalis strain DENG1 - Yu_2014_Arch.Microbiol_196_513 |
| Author(s) : Yu Z , Chen Z , Cheng H , Zheng J , Li D , Deng X , Pan W , Yang W , Deng Q |
| Ref : Arch Microbiol , 196 :513 , 2014 |
| Abstract : |
| PubMedSearch : Yu_2014_Arch.Microbiol_196_513 |
| PubMedID: 24800692 |
| Title : Differential efficiency in exogenous DNA acquisition among closely related Salmonella strains: implications in bacterial speciation - Bao_2014_BMC.Microbiol_14_157 |
| Author(s) : Bao HX , Tang L , Yu L , Wang XY , Li Y , Deng X , Li YG , Li A , Zhu DL , Johnston RN , Liu GR , Feng Y , Liu SL |
| Ref : BMC Microbiol , 14 :157 , 2014 |
| Abstract : |
| PubMedSearch : Bao_2014_BMC.Microbiol_14_157 |
| PubMedID: 24928416 |
| Gene_locus related to this paper: salbn-a0a068cr75 |
| Title : Determination of tacrine-6-ferulic acid in rat plasma by LC-MS\/MS and its application to pharmacokinetics study - Sun_2014_Biomed.Chromatogr_28_1352 |
| Author(s) : Sun X , Zhang P , Pi R , Zhou Y , Deng X , Xie Z , Liao Q |
| Ref : Biomedical Chromatography , 28 :1352 , 2014 |
| Abstract : |
| PubMedSearch : Sun_2014_Biomed.Chromatogr_28_1352 |
| PubMedID: 24706520 |
| Title : Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet - Zhang_2008_Circ.Res_102_250 |
| Author(s) : Zhang X , Qi R , Xian X , Yang F , Blackstein M , Deng X , Fan J , Ross C , Karasinska J , Hayden MR , Liu G |
| Ref : Circulation Research , 102 :250 , 2008 |
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| PubMedSearch : Zhang_2008_Circ.Res_102_250 |
| PubMedID: 18032735 |
| Title : Synthesis of fenthion sulfoxide and fenoxon sulfoxide enantiomers: effect of sulfur chirality on acetylcholinesterase activity - Gadepalli_2007_Chem.Res.Toxicol_20_257 |
| Author(s) : Gadepalli RS , Rimoldi JM , Fronczek FR , Nillos M , Gan J , Deng X , Rodriguez-Fuentes G , Schlenk D |
| Ref : Chemical Research in Toxicology , 20 :257 , 2007 |
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| PubMedSearch : Gadepalli_2007_Chem.Res.Toxicol_20_257 |
| PubMedID: 17253727 |