mondo-d2x2i8

 
Monodelphis domestica (Short-tailed gray opossum) Neuroligin 3

Comment
F7CLM0 F7CLM5 fragments missing


Relationship
Family Neuroligin
Block C
Monodelphis domestica position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Metatheria: N E > Didelphimorphia: N E > Didelphidae: N E > Didelphinae: N E > Monodelphis: N E > Monodelphis domestica: N E

Molecular evidence
Database
No mutation
No structure
No kinetic



1 Genbank : GQ489219
2 UniProt : D2X2I8, F7CLF4
2 UniProtTrembl : D2X2I8, F7CLF4
2 Interpro : D2X2I8, F7CLF4
2 Prodom : D2X2I8, F7CLF4
2 Pfam : D2X2I8, F7CLF4
2 PIRSF : D2X2I8, F7CLF4
2 SUPERFAM : D2X2I8, F7CLF4
2 QuickSwissBlast : D2X2I8, F7CLF4
 
Sequence
Graphical view for this peptide sequence: mondo-d2x2i8
Colored MSA for Neuroligin (raw)
MWLRLCPLSLPLSPEPTAGRSLCLLLWILSLLLRASAQAPAPTVNTHFGK
LRGSRVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNAT
HFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNIYVPT
EDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNEGDEDEDIRDSGAK
PVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQ
AAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS
HHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVD
CLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD
IMLGVNQGEGLKFVEAVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTL
RETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP
TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGIPMVGPTDLFPCNFSKND
VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRD
QLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPP
DTTHSSHITRRPNGKAWSTKRPAISPAYSNENAQGTWNGDQDAGPLLVEN
PRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGS
GGPGEMGAAPEEELAALQLGPSHHECEGPPTHDPLRLSALPDYTLTLRRS
PDDIPLMTPNTITMIPNSLVGLQTLHPYNTFASGFNSTGLPHSHSTTRV
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MWLRLCPLSLPLSPEPTAGRSLCLLLWILSLLLRASAQAPAPTVNTHFGK
LRGSRVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNAT
HFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNIYVPT
EDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNEGDEDEDIRDSGAK
PVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQ
AAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS
HHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVD
CLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD
IMLGVNQGEGLKFVEAVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTL
RETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP
TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGIPMVGPTDLFPCNFSKND
VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRD
QLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPP
DTTHSSHITRRPNGKAWSTKRPAISPAYSNENAQGTWNGDQDAGPLLVEN
PRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGS
GGPGEMGAAPEEELAALQLGPSHHECEGPPTHDPLRLSALPDYTLTLRRS
PDDIPLMTPNTITMIPNSLVGLQTLHPYNTFASGFNSTGLPHSHSTTRV

no DNA




References
    Title: Characterization of the neuroligin gene family expression and evolution in zebrafish
    Rissone A, Sangiorgio L, Monopoli M, Beltrame M, Zucchi I, Bussolino F, Arese M, Cotelli F
    Ref: Developmental Dynamics, 239:688, 2010 : PubMed

            

    Title: Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
    Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber M, Gentles AJ, Goodstadt L and Lindblad-Toh K <52 more author(s)>
    Ref: Nature, 447:167, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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