(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Opisthokonta: NE > Metazoa: NE > Eumetazoa: NE > Cnidaria: NE > Anthozoa: NE > Hexacorallia: NE > Actiniaria: NE > Edwardsiidae: NE > Nematostella: NE > Nematostella vectensis: NE
MNVSFCLLVVLLGNQLCCLLAKGTRPKWGPVDPDVNRNVSQLIHNRGFPV
EEHDVITKDGYILSVQRIPHGRKGRESPGPRPVVFLQHGLLADSSCFVQS
WEYDSLGYILADNGYDVWLGNIRGNRYSRSHVKYNHKQREFWDFSFEEFG
EYDIPAMIEHALSVSGQSQLYYIGHSQGTLVGFISFSTHPEIAKKVKRFI
ALAPIFHLNHTATIVRDAAFTLGPIQELLFPLGPTQFFPGYLIKLLTKLG
FCGGKYKAKLCYDISELIFGFDDGNANMSRVPVFFTHFPSGTSFKNIIHF
GQIVYYGRTARFDYGKRRNMKRYGKPKPPVYDVTKMDVPTALILGTHDNL
STVPDVAPIRAQIPHVTFYEVIPEWNHIDFVAGIDAYKLLYPKLLNLLQE
FE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MNVSFCLLVVLLGNQLCCLLAKGTRPKWGPVDPDVNRNVSQLIHNRGFPV EEHDVITKDGYILSVQRIPHGRKGRESPGPRPVVFLQHGLLADSSCFVQS WEYDSLGYILADNGYDVWLGNIRGNRYSRSHVKYNHKQREFWDFSFEEFG EYDIPAMIEHALSVSGQSQLYYIGHSQGTLVGFISFSTHPEIAKKVKRFI ALAPIFHLNHTATIVRDAAFTLGPIQELLFPLGPTQFFPGYLIKLLTKLG FCGGKYKAKLCYDISELIFGFDDGNANMSRVPVFFTHFPSGTSFKNIIHF GQIVYYGRTARFDYGKRRNMKRYGKPKPPVYDVTKMDVPTALILGTHDNL STVPDVAPIRAQIPHVTFYEVIPEWNHIDFVAGIDAYKLLYPKLLNLLQE FE
Sea anemones are seemingly primitive animals that, along with corals, jellyfish, and hydras, constitute the oldest eumetazoan phylum, the Cnidaria. Here, we report a comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis. The sea anemone genome is complex, with a gene repertoire, exon-intron structure, and large-scale gene linkage more similar to vertebrates than to flies or nematodes, implying that the genome of the eumetazoan ancestor was similarly complex. Nearly one-fifth of the inferred genes of the ancestor are eumetazoan novelties, which are enriched for animal functions like cell signaling, adhesion, and synaptic transmission. Analysis of diverse pathways suggests that these gene "inventions" along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor.
