KS07
KS07 IC 50 ACHE 13.5 nM activity against lipid peroxidation. Reduced inflammation in vivo, which can be correlated with their antioxidant activity
General
Type : Multitarget, Piperidine, Dimethoxyphenyl, Benzylpiperidine, Derivative of Donepezil, Hydroxycinnamic-ester, Cinnamate, Acrylate
Chemical_Nomenclature : (E)-2-(4-benzylpiperazin-1-yl)ethyl 3-(3,4-dimethoxyphenyl)acrylate
Canonical SMILES : C1(=C(C=C(C=C1)C=CC(OCCN2CCN(CC2)CC3=CC=CC=C3)=O)OC)OC
InChI : InChI=1S\/C24H30N2O4\/c1-28-22-10-8-20(18-23(22)29-2)9-11-24(27)30-17-16-25-12-14-26(15-13-25)19-21-6-4-3-5-7-21\/h3-11,18H,12-17,19H2,1-2H3
InChIKey : FPFLDYJTGNOKCZ-UHFFFAOYSA-N
Other name(s) :
Target
References (1)
| Title : Synthesis and Evaluation of Novel Cinnamic Acid Hybrids With Antiacetylcholinesterase, Antioxidant, and Anti-Inflammatory Properties - Sdougkou_2026_ChemMedChem_21_e70343 |
| Author(s) : Sdougkou K , Rekka E , Papagiannopoulou D |
| Ref : ChemMedChem , 21 :e70343 , 2026 |
| Abstract : |
| PubMedSearch : Sdougkou_2026_ChemMedChem_21_e70343 |
| PubMedID: 42271174 |