Acrylate

General

Acrylates and methacrylates (the salts and esters of methacrylic acid) are common monomers in polymer plastics

Inhibitor	Main targeted enzyme families	Type
KS07		Multitarget Piperidine Dimethoxyphenyl Benzylpiperidine Derivative of Donepezil Hydroxycinnamic-ester Cinnamate Acrylate
KS12		Multitarget Piperidine Dimethoxyphenyl Benzylpiperidine Derivative of Donepezil Hydroxycinnamic-ester Sinapyl Cinnamate Acrylate
Nlrp3-IN-33-Cpd12o	ACHE BCHE	Acrylate Feruloyl Quinoline Hydroxycinnamic-ester Multitarget Cinnamate NLRP3 inflammasome activation
Tacrine-cinnamic-hybrid-cpd10g	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Hydroxycinnamic-ester Alkyl linked bis-ligand Cinnamate
CHEMBL4533477	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand Nitrobenzyl Cinnamate
CHEMBL4534662	ACHE BCHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Cinnamate Alkyl linked bis-ligand
Dioxothiazolidin-benzothiazol-methoxyphenyl-acrylamide-Cpd49	ACHE	Monoamine-oxidase-inhibitor Multitarget BACE1-inhibitor Carboxamide Acrylate Benzothiazol Thiazole Dioxothiazolidine Sulfur Compound
Caffeic-acid-phenethyl-ester	BCHE ACHE Canar_LipB	Hydroxycinnamic-ester Acrylate Not AlphaBeta Hydrolase target Natural Dihydroxyphenyl Cinnamate
TFAH-tacrine-ferulic-acid-hybrid-10n	BCHE	Multitarget Acrylate Antioxidant Derivative of Tacrine Acridine Hydroxycinnamic-ester Cinnamate Alkyl linked bis-ligand
Caffeic-acid	FAE-Bacterial-promiscuous	Hydroxycinnamic-ester Cinnamate Acrylate Antioxidant Dihydroxyphenyl
Tacrine-Melatonin-Feruloyl-5c	BCHE ACHE	Derivative of Tacrine Acridine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand Nrf2 modulator Cinnamate