Phenethyl-Propargylpiperidine-carbamate-Cpd15
compound 15 hMAO-B IC(50) 4.3 microM and hBChE IC(50) of 8.5 microM
General
Type : Multitarget, Propargyl, Alkyne, Monoamine-oxidase-inhibitor, Piperidine, Carbamate
Chemical_Nomenclature : 3-(2-(1-(prop-2-yn-1-yl)piperidin-4-yl)ethyl)phenyl ethyl(methyl)carbamate
Canonical SMILES : N1(CCC(CC1)CCC2=CC=C(C=C2)OC(N(C)CC)=O)CC#C
InChI : InChI=1S\/C20H28N2O2\/c1-4-14-22-15-12-18(13-16-22)7-6-17-8-10-19(11-9-17)24-20(23)21(3)5-2\/h1,8-11,18H,5-7,12-16H2,2-3H3
InChIKey : YMOARNSIHRNADO-UHFFFAOYSA-N
Other name(s) :
Target
Families : Phenethyl-Propargylpiperidine-carbamate-Cpd15 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B - Mazej_2021_Molecules_26_ |
| Author(s) : Mazej T , Knez D , Meden A , Gobec S , Sova M |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Mazej_2021_Molecules_26_ |
| PubMedID: 34299393 |