Phenothiazin-piperidin-inden-one-CpdC11
General
Type : Derivative of Donepezil, Phenothiazine, Multitarget, Sulfur Compound, Piperidine, Inden, anti-tau-aggregation, Indole
Chemical_Nomenclature : 5,6-Dimethoxy-2-((1-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)piperidin-4-yl)methyl)-2,3-dihydro-1H-inden-1-one
Canonical SMILES : C1=CC3=C(C=C1)N(C2=CC=CC=C2S3)C(CN4CCC(CC4)CC6C(C5=CC(=C(C=C5C6)OC)OC)=O)=O
InChI : InChI=1S\/C31H32N2O4S\/c1-36-26-17-21-16-22(31(35)23(21)18-27(26)37-2)15-20-11-13-32(14-12-20)19-30(34)33-24-7-3-5-9-28(24)38-29-10-6-4-8-25(29)33\/h3-10,17-18,20,22H,11-16,19H2,1-2H3
InChIKey : SWHOXGJDWONGJP-UHFFFAOYSA-N
Other name(s) : Compound C11
Target
Families : Phenothiazin-piperidin-inden-one-CpdC11 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Hybrid molecules with dual inhibition of acetylcholinesterase and Tau hyperphosphorylation: design, inhibitory activity evaluation, apoptosis assessment, and mechanistic exploration - Hu_2025_Chem.Biol.Interact__111848 |
| Author(s) : Hu Q , Xu K , Ran Q , Zhang W , Gan C , Fang Q , Hui A |
| Ref : Chemico-Biological Interactions , :111848 , 2025 |
| Abstract : |
| PubMedSearch : Hu_2025_Chem.Biol.Interact__111848 |
| PubMedID: 41285280 |