SCHEMBL20516363
IC50 value lower than 100 nM for ABHD6 and between 100 nM and 1 microM for Lp-PLA2 WO-2017059135 patent by Abide Therapeutics, Inc
General
Type : Piperazine, Imidazole, Carbamate, Morpholine
Chemical_Nomenclature : [(4R)-2,5-dioxo-4-propan-2-ylimidazolidin-1-yl] 4-[2-chloro-3-(morpholine-4-carbonyl)phenyl]piperazine-1-carboxylate
Canonical SMILES : CC(C)C1C(=O)N(C(=O)N1)OC(=O)N2CCN(CC2)C3=CC=CC(=C3Cl)C(=O)N4CCOCC4
InChI : InChI=1S\/C22H28ClN5O6\/c1-14(2)18-20(30)28(21(31)24-18)34-22(32)27-8-6-25(7-9-27)16-5-3-4-15(17(16)23)19(29)26-10-12-33-13-11-26\/h3-5,14,18H,6-13H2,1-2H3,(H,24,31)\/t18-\/m1\/s1
InChIKey : MAAXHKBCVMPHBI-GOSISDBHSA-N
Other name(s) : SCHEMBL20516418 || SCHEMBL20516364
MW : 493.9
Formula : C22H28ClN5O6
CAS_number :
PubChem : 135342129
UniChem : MAAXHKBCVMPHBI-GOSISDBHSA-N
Target
Families : SCHEMBL20516363 ligand of proteins in family
ABHD6-Lip
PAF-Acetylhydrolase
Protein :
human-ABHD6
human-PLA2G7
References
No reference