SCHEMBL8072716
Memoquine Lipocrine combined: humanAChE IC50 0.15 microM humanBChE IC50 21 microM
General
Type : Multitarget, BACE1-inhibitor, Derivative of Memoquin, Antioxidant, Alkyl linked bis-ligand, Sulfur Compound
Chemical_Nomenclature : 5-(dithiolan-3-yl)-N-[3-[[4-[6-[ethyl-[(2-methoxyphenyl)methyl]amino]hexylamino]-3,6-dioxocyclohexa-1,4-dien-1-yl]amino]propyl]pentanamide
Canonical SMILES : CCN(CCCCCCNC1=CC(=O)C(=CC1=O)NCCCNC(=O)CCCCC2CCSS2)CC3=CC=CC=C3OC
InChI : InChI=1S\/C33H50N4O4S2\/c1-3-37(25-26-13-6-8-15-32(26)41-2)21-11-5-4-10-18-34-28-23-31(39)29(24-30(28)38)35-19-12-20-36-33(40)16-9-7-14-27-17-22-42-43-27\/h6,8,13,15,23-24,27,34-35H,3-5,7,9-12,14,16-22,25H2,1-2H3,(H,36,40)
InChIKey : WUQZNYSVERYXKI-UHFFFAOYSA-N
Other name(s) : Compound 4
MW : 630.9
Formula : C33H50N4O4S2
CAS_number :
PubChem : 45483660
UniChem : WUQZNYSVERYXKI-UHFFFAOYSA-N
Target
References (1)
| Title : Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks - Bolognesi_2009_J.Med.Chem_52_7883 |
| Author(s) : Bolognesi ML , Cavalli A , Bergamini C , Fato R , Lenaz G , Rosini M , Bartolini M , Andrisano V , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 52 :7883 , 2009 |
| Abstract : |
| PubMedSearch : Bolognesi_2009_J.Med.Chem_52_7883 |
| PubMedID: 19813747 |