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DEPQ

fluorescent leaving group is 7HMC (7-hydroxy-4-methylcoumarin)

General

Type : Organophosphate,Quinoline

Chemical_Nomenclature : diethyl (1-methylquinolin-1-ium-7-yl) phosphate

Canonical SMILES : CCOP(=O)(OCC)OC1=CC2=C(C=CC=[N+]2C)C=C1

InChI : InChI=1S\/C14H19NO4P\/c1-4-17-20(16,18-5-2)19-13-9-8-12-7-6-10-15(3)14(12)11-13\/h6-11H,4-5H2,1-3H3\/q+1

InChIKey : CVKRJKJYOIKAHS-UHFFFAOYSA-N

Other name(s) : 7-[(diethoxyphosphoryl)oxy]-1-methylquinolinium iodide

MW : 296.28

Formula : C14H19NO4P+

CAS_number :

PubChem : 10402289

UniChem : CVKRJKJYOIKAHS-UHFFFAOYSA-N

Target

Families : DEPQ ligand of proteins in family
ACHE

References (2)

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
Abstract : Luo_1999_Chem.Biol.Interact_119-120_129
ESTHER : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedSearch : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedID: 10421446

Title : Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands. Distinct effects of propidium and fasciculin - Mallender_1999_J.Biol.Chem_274_8491
Author(s) : Mallender WD , Szegletes T , Rosenberry TL
Ref : Journal of Biological Chemistry , 274 :8491 , 1999
Abstract : Mallender_1999_J.Biol.Chem_274_8491
ESTHER : Mallender_1999_J.Biol.Chem_274_8491
PubMedSearch : Mallender_1999_J.Biol.Chem_274_8491
PubMedID: 10085081 
Array
(
    [id] => 4983
    [inhibitor] => DEPQ
    [type] => Array
        (
            [0] => Organophosphate
            [1] => Quinoline
        )

    [other_name] => Array
        (
            [0] => 7-[(diethoxyphosphoryl)oxy]-1-methylquinolinium iodide
        )

    [chemical_nomenclature] => diethyl (1-methylquinolin-1-ium-7-yl) phosphate
    [formula] => C14H19NO4P+
    [cas_number] => 
    [mw] => 296.28
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Luo_1999_Chem.Biol.Interact_119-120_129 || Mallender_1999_J.Biol.Chem_274_8491
    [comment] => fluorescent leaving group is 7HMC (7-hydroxy-4-methylcoumarin)
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 10402289
    [family] => ACHE
    [inchikey] => CVKRJKJYOIKAHS-UHFFFAOYSA-N
    [canonicalsmiles] => CCOP(=O)(OCC)OC1=CC2=C(C=CC=[N+]2C)C=C1
    [inchi] => InChI=1S\/C14H19NO4P\/c1-4-17-20(16,18-5-2)19-13-9-8-12-7-6-10-15(3)14(12)11-13\/h6-11H,4-5H2,1-3H3\/q+1
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)