| Title : Comparative genomics of Listeria species - Glaser_2001_Science_294_849 |
| Author(s) : Glaser P , Frangeul L , Buchrieser C , Rusniok C , Amend A , Baquero F , Berche P , Bloecker H , Brandt P , Chakraborty T , Charbit A , Chetouani F , Couve E , de Daruvar A , Dehoux P , Domann E , Dominguez-Bernal G , Duchaud E , Durant L , Dussurget O , Entian KD , Fsihi H , Portillo FG , Garrido P , Gautier L , Goebel W , Gomez-Lopez N , Hain T , Hauf J , Jackson D , Jones LM , Kaerst U , Kreft J , Kuhn M , Kunst F , Kurapkat G , Madueno E , Maitournam A , Vicente JM , Ng E , Nedjari H , Nordsiek G , Novella S , de Pablos B , Perez-Diaz JC , Purcell R , Remmel B , Rose M , Schlueter T , Simoes N , Tierrez A , Vazquez-Boland JA , Voss H , Wehland J , Cossart P |
| Ref : Science , 294 :849 , 2001 |
|
Abstract :
Listeria monocytogenes is a food-borne pathogen with a high mortality rate that has also emerged as a paradigm for intracellular parasitism. We present and compare the genome sequences of L. monocytogenes (2,944,528 base pairs) and a nonpathogenic species, L. innocua (3,011,209 base pairs). We found a large number of predicted genes encoding surface and secreted proteins, transporters, and transcriptional regulators, consistent with the ability of both species to adapt to diverse environments. The presence of 270 L. monocytogenes and 149 L. innocua strain-specific genes (clustered in 100 and 63 islets, respectively) suggests that virulence in Listeria results from multiple gene acquisition and deletion events. |
| PubMedSearch : Glaser_2001_Science_294_849 |
| PubMedID: 11679669 |
| Gene_locus related to this paper: lisin-LIN0589 , lisin-LIN0754 , lisin-LIN0850 , lisin-LIN0949 , lisin-LIN0950 , lisin-LIN0976 , lisin-LIN1094 , lisin-LIN1546 , lisin-LIN1782 , lisin-LIN2180 , lisin-LIN2214 , lisin-LIN2363 , lisin-LIN2527 , lisin-LIN2544 , lisin-LIN2547 , lisin-LIN2722 , lisin-LIN2825 , lisin-LIN2898 , lismc-c1l0d9 , lismo-LMO0110 , lismo-LMO0493 , lismo-LMO0580 , lismo-LMO0752 , lismo-LMO0760 , lismo-LMO0857 , lismo-LMO0950 , lismo-LMO0951 , lismo-LMO0977 , lismo-LMO1128 , lismo-LMO1258 , lismo-LMO1511 , lismo-LMO1674 , lismo-LMO2074 , lismo-LMO2089 , lismo-LMO2109 , lismo-LMO2262 , lismo-LMO2433 , lismo-LMO2450 , lismo-LMO2452 , lismo-LMO2453 , lismo-LMO2578 , lismo-LMO2677 , lismo-LMO2755 , lismo-metx |
Glaser P, Frangeul L, Buchrieser C, Rusniok C, Amend A, Baquero F, Berche P, Bloecker H, Brandt P, Chakraborty T, Charbit A, Chetouani F, Couve E, de Daruvar A, Dehoux P, Domann E, Dominguez-Bernal G, Duchaud E, Durant L, Dussurget O, Entian KD, Fsihi H, Portillo FG, Garrido P, Gautier L, Goebel W, Gomez-Lopez N, Hain T, Hauf J, Jackson D, Jones LM, Kaerst U, Kreft J, Kuhn M, Kunst F, Kurapkat G, Madueno E, Maitournam A, Vicente JM, Ng E, Nedjari H, Nordsiek G, Novella S, de Pablos B, Perez-Diaz JC, Purcell R, Remmel B, Rose M, Schlueter T, Simoes N, Tierrez A, Vazquez-Boland JA, Voss H, Wehland J, Cossart P (2001)
Comparative genomics of Listeria species
Science
294 :849
Glaser P, Frangeul L, Buchrieser C, Rusniok C, Amend A, Baquero F, Berche P, Bloecker H, Brandt P, Chakraborty T, Charbit A, Chetouani F, Couve E, de Daruvar A, Dehoux P, Domann E, Dominguez-Bernal G, Duchaud E, Durant L, Dussurget O, Entian KD, Fsihi H, Portillo FG, Garrido P, Gautier L, Goebel W, Gomez-Lopez N, Hain T, Hauf J, Jackson D, Jones LM, Kaerst U, Kreft J, Kuhn M, Kunst F, Kurapkat G, Madueno E, Maitournam A, Vicente JM, Ng E, Nedjari H, Nordsiek G, Novella S, de Pablos B, Perez-Diaz JC, Purcell R, Remmel B, Rose M, Schlueter T, Simoes N, Tierrez A, Vazquez-Boland JA, Voss H, Wehland J, Cossart P (2001)
Science
294 :849