Name : Human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-N-(2-methoxyethyl)-2-naphthamide

Revelation date : 22-Oct-2014

Family : BCHE

Gene_locus : human-BCHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Brus, B., Kosak U, Stojan, J., Turk, S., Pislar, A., Coquelle, N., Colletier, J.P., Kos, J., Gobec, S.

Ligand : Inhibitor 3F9 Ligand in structure: Ligplot

References (1)

Title : Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor - Brus_2014_J.Med.Chem_57_8167
Author(s) : Brus B , Kosak U , Turk S , Pislar A , Coquelle N , Kos J , Stojan J , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 57 :8167 , 2014
Abstract :
PubMedSearch : Brus_2014_J.Med.Chem_57_8167
PubMedID: 25226236
Gene_locus related to this paper: human-BCHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 4TPK Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4TPK Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4TPK Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4TPK 3D, interactive encyclopedia of proteins - PROTEOPEDIA server