Kosak U

References (11)

Title : Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors - Gajic_2022_ChemMedChem__
Author(s) : Gajic M , Knez D , Sosic I , Mravljak J , Meden A , Kosak U , Leitzbach L , George S , Hofmann B , Zivkovic A , Steinhilber D , Stark H , Gobec S , Smelcerovic A , Anderluh M
Ref : ChemMedChem , : , 2022
PubMedID: 34994078

Title : Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease - Rejc_2021_Theranostics_11_6542
Author(s) : Rejc L , Gomez-Vallejo V , Joya A , Moreno O , Egimendia A , Castellnou P , Rios-Anglada X , Cossio U , Baz Z , Passannante R , Tobalina-Larrea I , Ramos-Cabrer P , Giralt A , Sastre M , Capetillo-Zarate E , Kosak U , Knez D , Gobec S , Marder M , Martin A , Llop J
Ref : Theranostics , 11 :6542 , 2021
PubMedID: 33995675

Title : Synthesis and Initial Characterization of a Reversible, Selective (18)F-Labeled Radiotracer for Human Butyrylcholinesterase - Gentzsch_2021_Mol.Imaging.Biol__
Author(s) : Gentzsch C , Chen X , Spatz P , Kosak U , Knez D , Nose N , Gobec S , Higuchi T , Decker M
Ref : Mol Imaging Biol , : , 2021
PubMedID: 33660167

Title : Treatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitor - Zakosek Pipan_2021_Sci.Rep_11_18098
Author(s) : Zakosek Pipan M , Prpar Mihevc S , Strbenc M , Kosak U , German Ilic I , Trontelj J , Zakelj S , Gobec S , Pavlin D , Majdic G
Ref : Sci Rep , 11 :18098 , 2021
PubMedID: 34518582

Title : N-alkylpiperidine carbamates as potential anti-Alzheimer's agents - Kosak_2020_Eur.J.Med.Chem_197_112282
Author(s) : Kosak U , Strasek N , Knez N , Jukic M , Zakelj S , Zahirovic A , Pislar A , Brazzolotto X , Nachon F , Kos J , Gobec S , Knez D
Ref : Eur Journal of Medicinal Chemistry , 197 :112282 , 2020
PubMedID: 32380361
Gene_locus related to this paper: human-BCHE

Title : Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes - Pajk_2020_J.Enzyme.Inhib.Med.Chem_35_498
Author(s) : Pajk S , Knez D , Kosak U , Zorovic M , Brazzolotto X , Coquelle N , Nachon F , Colletier JP , Zivin M , Stojan J , Gobec S
Ref : J Enzyme Inhib Med Chem , 35 :498 , 2020
PubMedID: 31914836
Gene_locus related to this paper: human-BCHE

Title : The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity - Kosak_2018_J.Med.Chem_61_119
Author(s) : Kosak U , Brus B , Knez D , Zakelj S , Trontelj J , Pislar A , Sink R , Jukic M , Zivin M , Podkowa A , Nachon F , Brazzolotto X , Stojan J , Kos J , Coquelle N , Salat K , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 61 :119 , 2018
PubMedID: 29227101
Gene_locus related to this paper: human-BCHE

Title : Dual inhibitors of cholinesterases and monoamine oxidases for Alzheimer's disease - Knez_2017_Future.Med.Chem_9_811
Author(s) : Knez D , Sova M , Kosak U , Gobec S
Ref : Future Med Chem , 9 :811 , 2017
PubMedID: 28504893

Title : N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents - Kosak_2017_Bioorg.Med.Chem_25_633
Author(s) : Kosak U , Knez D , Coquelle N , Brus B , Pislar A , Nachon F , Brazzolotto X , Kos J , Colletier JP , Gobec S
Ref : Bioorganic & Medicinal Chemistry , 25 :633 , 2017
PubMedID: 27908752
Gene_locus related to this paper: human-BCHE

Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495
Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S
Ref : Sci Rep , 6 :39495 , 2016
PubMedID: 28000737
Gene_locus related to this paper: human-BCHE

Title : Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor - Brus_2014_J.Med.Chem_57_8167
Author(s) : Brus B , Kosak U , Turk S , Pislar A , Coquelle N , Kos J , Stojan J , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 57 :8167 , 2014
PubMedID: 25226236
Gene_locus related to this paper: human-BCHE