Name : Crystal structure of Torpedo Californica acetylcholinesterase in complex with 2-{1-[2-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]-1H-1,2,3-triazol-4-yl}-N-[4-(hydroxy)-3-methoxybenzyl]acetamide

Revelation date : 04-Apr-2018

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Coquelle, N., Colletier, J.P. (This entry supersedes: 6FOV)

Ligand : Inhibitor E0Z Ligand in structure: Ligplot

References (1)

Title : Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis - Galdeano_2018_Molecules_23_
Author(s) : Galdeano C , Coquelle N , Cieslikiewicz-Bouet M , Bartolini M , Perez B , Clos MV , Silman I , Jean L , Colletier JP , Renard PY , Munoz-Torrero D
Ref : Molecules , 23 : , 2018
Abstract :
PubMedSearch : Galdeano_2018_Molecules_23_
PubMedID: 29534488
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 6G1W Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6G1W Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6G1W Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6G1W 3D, interactive encyclopedia of proteins - PROTEOPEDIA server