Full name : Clos M.Victoria
First name : M.Victoria
Mail : Dept Farmacologia\; Terapeutica i Toxicologia. Fac Medicina. Universitat Autonoma de Barcelona (Bellaterra)\; 08193 Barcelona
Zip Code :
City :
Country : Spain
Email : victoria.clos@uab.es
Phone : +935811952
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Website :
Directory :
Comment
| Title : Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis - Galdeano_2018_Molecules_23_ |
| Author(s) : Galdeano C , Coquelle N , Cieslikiewicz-Bouet M , Bartolini M , Perez B , Clos MV , Silman I , Jean L , Colletier JP , Renard PY , Munoz-Torrero D |
| Ref : Molecules , 23 : , 2018 |
| Abstract : |
| PubMedSearch : Galdeano_2018_Molecules_23_ |
| PubMedID: 29534488 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice - Relat_2018_Int.J.Mol.Sci_19_ |
| Author(s) : Relat J , Come J , Perez B , Camps P , Munoz-Torrero D , Badia A , Gimenez-Llort L , Clos MV |
| Ref : Int J Mol Sci , 19 : , 2018 |
| Abstract : |
| PubMedSearch : Relat_2018_Int.J.Mol.Sci_19_ |
| PubMedID: 30181440 |
| Title : Behavioural effects of novel multitarget anticholinesterasic derivatives in Alzheimer's disease - Gimenez-Llort_2017_Behav.Pharmacol_28_124 |
| Author(s) : Gimenez-Llort L , Ratia M , Perez B , Camps P , Munoz-Torrero D , Badia A , Clos MV |
| Ref : Behav Pharmacol , 28 :124 , 2017 |
| Abstract : |
| PubMedSearch : Gimenez-Llort_2017_Behav.Pharmacol_28_124 |
| PubMedID: 28125507 |
| Title : AVCRI104P3, a novel multitarget compound with cognition-enhancing and anxiolytic activities: Studies in cognitively poor middle-aged mice - Gimenez-Llort_2015_Behav.Brain.Res_286_97 |
| Author(s) : Gimenez-Llort L , Ratia M , Perez B , Camps P , Munoz-Torrero D , Badia A , Clos MV |
| Ref : Behavioural Brain Research , 286 :97 , 2015 |
| Abstract : |
| PubMedSearch : Gimenez-Llort_2015_Behav.Brain.Res_286_97 |
| PubMedID: 25732954 |
| Title : Novel Levetiracetam Derivatives That Are Effective against the Alzheimer-like Phenotype in Mice: Synthesis, in Vitro, ex Vivo, and in Vivo Efficacy Studies - Sola_2015_J.Med.Chem_58_6018 |
| Author(s) : Sola I , Aso E , Frattini D , Lopez-Gonzalez I , Espargaro A , Sabate R , Di Pietro O , Luque FJ , Clos MV , Ferrer I , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 58 :6018 , 2015 |
| Abstract : |
| PubMedSearch : Sola_2015_J.Med.Chem_58_6018 |
| PubMedID: 26181606 |
| Title : Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity - Sola_2015_Bioorg.Med.Chem_23_5156 |
| Author(s) : Sola I , Castella S , Viayna E , Galdeano C , Taylor MC , Gbedema SY , Perez B , Clos MV , Jones DC , Fairlamb AH , Wright CW , Kelly JM , Munoz-Torrero D |
| Ref : Bioorganic & Medicinal Chemistry , 23 :5156 , 2015 |
| Abstract : |
| PubMedSearch : Sola_2015_Bioorg.Med.Chem_23_5156 |
| PubMedID: 25678015 |
| Title : Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity - Di Pietro_2015_Eur.J.Med.Chem_105_120 |
| Author(s) : Di Pietro O , Vicente-Garcia E , Taylor MC , Berenguer D , Viayna E , Lanzoni A , Sola I , Sayago H , Riera C , Fisa R , Clos MV , Perez B , Kelly JM , Lavilla R , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 105 :120 , 2015 |
| Abstract : |
| PubMedSearch : Di Pietro_2015_Eur.J.Med.Chem_105_120 |
| PubMedID: 26479031 |
| Title : Shogaol-huprine hybrids: Dual antioxidant and anticholinesterase agents with beta-amyloid and tau anti-aggregating properties - Perez-Areales_2014_Bioorg.Med.Chem_22_5298 |
| Author(s) : Perez-Areales FJ , Di Pietro O , Espargaro A , Vallverdu-Queralt A , Galdeano C , Ragusa IM , Viayna E , Guillou C , Clos MV , Perez B , Sabate R , Lamuela-Raventos RM , Luque FJ , Munoz-Torrero D |
| Ref : Bioorganic & Medicinal Chemistry , 22 :5298 , 2014 |
| Abstract : |
| PubMedSearch : Perez-Areales_2014_Bioorg.Med.Chem_22_5298 |
| PubMedID: 25156301 |
| Title : Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents - Viayna_2014_J.Med.Chem_57_2549 |
| Author(s) : Viayna E , Sola I , Bartolini M , De Simone A , Tapia-Rojas C , Serrano FG , Sabate R , Juarez-Jimenez J , Perez B , Luque FJ , Andrisano V , Clos MV , Inestrosa NC , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 57 :2549 , 2014 |
| Abstract : |
| PubMedSearch : Viayna_2014_J.Med.Chem_57_2549 |
| PubMedID: 24568372 |
| Title : Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting beta-amyloid, tau, and cholinesterase pathologies - Di Pietro_2014_Eur.J.Med.Chem_84C_107 |
| Author(s) : Di Pietro O , Perez-Areales FJ , Juarez-Jimenez J , Espargaro A , Clos MV , Perez B , Lavilla R , Sabate R , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 84C :107 , 2014 |
| Abstract : |
| PubMedSearch : Di Pietro_2014_Eur.J.Med.Chem_84C_107 |
| PubMedID: 25016233 |
| Title : Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines - Sola_2014_Bioorg.Med.Chem.Lett_24_5435 |
| Author(s) : Sola I , Artigas A , Taylor MC , Gbedema SY , Perez B , Clos MV , Wright CW , Kelly JM , Munoz-Torrero D |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :5435 , 2014 |
| Abstract : |
| PubMedSearch : Sola_2014_Bioorg.Med.Chem.Lett_24_5435 |
| PubMedID: 25454267 |
| Title : 1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: Synthesis, pharmacological evaluation and mechanistic studies - Di Pietro_2013_Eur.J.Med.Chem_73C_141 |
| Author(s) : Di Pietro O , Viayna E , Vicente-Garcia E , Bartolini M , Ramon R , Juarez-Jimenez J , Clos MV , Perez B , Andrisano V , Luque FJ , Lavilla R , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 73C :141 , 2013 |
| Abstract : |
| PubMedSearch : Di Pietro_2013_Eur.J.Med.Chem_73C_141 |
| PubMedID: 24389509 |
| Title : Huprine X and Huperzine A Improve Cognition and Regulate Some Neurochemical Processes Related with Alzheimer's Disease in Triple Transgenic Mice (3xTg-AD) - Ratia_2013_Neurodegener.Dis_11_129 |
| Author(s) : Ratia M , Gimenez-Llort L , Camps P , Munoz-Torrero D , Perez B , Clos MV , Badia A |
| Ref : Neurodegener Dis , 11 :129 , 2013 |
| Abstract : |
| PubMedSearch : Ratia_2013_Neurodegener.Dis_11_129 |
| PubMedID: 22626981 |
| Title : Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases - Galdeano_2012_J.Med.Chem_55_661 |
| Author(s) : Galdeano C , Viayna E , Sola I , Formosa X , Camps P , Badia A , Clos MV , Relat J , Ratia M , Bartolini M , Mancini F , Andrisano V , Salmona M , Minguillon C , Gonzalez-Munoz GC , Rodriguez-Franco MI , Bidon-Chanal A , Luque FJ , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 55 :661 , 2012 |
| Abstract : |
| PubMedSearch : Galdeano_2012_J.Med.Chem_55_661 |
| PubMedID: 22185619 |
| Title : Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents - Munoz-Torrero_2012_Neurodegener.Dis_10_96 |
| Author(s) : Munoz-Torrero D , Pera M , Relat J , Ratia M , Galdeano C , Viayna E , Sola I , Formosa X , Camps P , Badia A , Clos MV |
| Ref : Neurodegener Dis , 10 :96 , 2012 |
| Abstract : |
| PubMedSearch : Munoz-Torrero_2012_Neurodegener.Dis_10_96 |
| PubMedID: 22236498 |
| Title : Novel huprine derivatives with inhibitory activity toward beta-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates - Viayna_2010_ChemMedChem_5_1855 |
| Author(s) : Viayna E , Gomez T , Galdeano C , Ramirez L , Ratia M , Badia A , Clos MV , Verdaguer E , Junyent F , Camins A , Pallas M , Bartolini M , Mancini F , Andrisano V , Arce MP , Rodriguez-Franco MI , Bidon-Chanal A , Luque FJ , Camps P , Munoz-Torrero D |
| Ref : ChemMedChem , 5 :1855 , 2010 |
| Abstract : |
| PubMedSearch : Viayna_2010_ChemMedChem_5_1855 |
| PubMedID: 20859987 |
| Title : Effect of huprine X on beta-amyloid, synaptophysin and alpha7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice - Hedberg_2010_Neurodegener.Dis_7_379 |
| Author(s) : Hedberg MM , Clos MV , Ratia M , Gonzalez D , Lithner CU , Camps P , Munoz-Torrero D , Badia A , Gimenez-Llort L , Nordberg A |
| Ref : Neurodegener Dis , 7 :379 , 2010 |
| Abstract : |
| PubMedSearch : Hedberg_2010_Neurodegener.Dis_7_379 |
| PubMedID: 20689242 |
| Title : Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates - Camps_2010_Chem.Biol.Interact_187_411 |
| Author(s) : Camps P , Formosa X , Galdeano C , Gomez T , Munoz-Torrero D , Ramirez L , Viayna E , Gomez E , Isambert N , Lavilla R , Badia A , Clos MV , Bartolini M , Mancini F , Andrisano V , Bidon-Chanal A , Huertas O , Dafni T , Luque FJ |
| Ref : Chemico-Biological Interactions , 187 :411 , 2010 |
| Abstract : |
| PubMedSearch : Camps_2010_Chem.Biol.Interact_187_411 |
| PubMedID: 20167211 |
| Title : Acetylcholinesterase as an amyloid enhancing factor in PrP82-146 aggregation process - Pera_2009_Mol.Cell.Neurosci_40_217 |
| Author(s) : Pera M , Martinez-Otero A , Colombo L , Salmona M , Ruiz-Molina D , Badia A , Clos MV |
| Ref : Molecular & Cellular Neurosciences , 40 :217 , 2009 |
| Abstract : |
| PubMedSearch : Pera_2009_Mol.Cell.Neurosci_40_217 |
| PubMedID: 19038345 |
| Title : Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds - Camps_2009_J.Med.Chem_52_5365 |
| Author(s) : Camps P , Formosa X , Galdeano C , Munoz-Torrero D , Ramirez L , Gomez E , Isambert N , Lavilla R , Badia A , Clos MV , Bartolini M , Mancini F , Andrisano V , Arce MP , Rodriguez-Franco MI , Huertas O , Dafni T , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 52 :5365 , 2009 |
| Abstract : |
| PubMedSearch : Camps_2009_J.Med.Chem_52_5365 |
| PubMedID: 19663388 |
| Title : Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation - Camps_2008_J.Med.Chem_51_3588 |
| Author(s) : Camps P , Formosa X , Galdeano C , Gomez T , Munoz-Torrero D , Scarpellini M , Viayna E , Badia A , Clos MV , Camins A , Pallas M , Bartolini M , Mancini F , Andrisano V , Estelrich J , Lizondo M , Bidon-Chanal A , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 51 :3588 , 2008 |
| Abstract : |
| PubMedSearch : Camps_2008_J.Med.Chem_51_3588 |
| PubMedID: 18517184 |
| Title : Effect of acetylcholinesterase inhibitors on AChE-induced PrP106-126 aggregation - Clos_2006_J.Mol.Neurosci_30_89 |
| Author(s) : Clos MV , Pera M , Ratia M , Roman S , Camps P , Munoz-Torrero D , Colombo L , Salmona M , Badia A |
| Ref : Journal of Molecular Neuroscience , 30 :89 , 2006 |
| Abstract : |
| PubMedSearch : Clos_2006_J.Mol.Neurosci_30_89 |
| PubMedID: 17192641 |
| Title : Acetylcholinesterase triggers the aggregation of PrP 106-126 - Pera_2006_Biochem.Biophys.Res.Commun_346_89 |
| Author(s) : Pera M , Roman S , Ratia M , Camps P , Munoz-Torrero D , Colombo L , Manzoni C , Salmona M , Badia A , Clos MV |
| Ref : Biochemical & Biophysical Research Communications , 346 :89 , 2006 |
| Abstract : |
| PubMedSearch : Pera_2006_Biochem.Biophys.Res.Commun_346_89 |
| PubMedID: 16750169 |
| Title : Binding of 13-amidohuprines to acetylcholinesterase: exploring the ligand-induced conformational change of the gly117-gly118 peptide bond in the oxyanion hole - Camps_2006_J.Med.Chem_49_6833 |
| Author(s) : Camps P , Gomez E , Munoz-Torrero D , Badia A , Clos MV , Curutchet C , Munoz-Muriedas J , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 49 :6833 , 2006 |
| Abstract : |
| PubMedSearch : Camps_2006_J.Med.Chem_49_6833 |
| PubMedID: 17154513 |
| Title : Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors - Roman_2005_Brain.Res_1061_73 |
| Author(s) : Roman S , Badia A , Camps P , Munoz-Torrero D , Clos MV |
| Ref : Brain Research , 1061 :73 , 2005 |
| Abstract : |
| PubMedSearch : Roman_2005_Brain.Res_1061_73 |
| PubMedID: 16248990 |
| Title : Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors - Camps_2005_J.Med.Chem_48_1701 |
| Author(s) : Camps P , Formosa X , Munoz-Torrero D , Petrignet J , Badia A , Clos MV |
| Ref : Journal of Medicinal Chemistry , 48 :1701 , 2005 |
| Abstract : |
| PubMedSearch : Camps_2005_J.Med.Chem_48_1701 |
| PubMedID: 15771413 |
| Title : Potentiation effects of (+\/-)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes - Roman_2004_Neuropharmacol_46_95 |
| Author(s) : Roman S , Badia A , Camps P , Clos MV |
| Ref : Neuropharmacology , 46 :95 , 2004 |
| Abstract : |
| PubMedSearch : Roman_2004_Neuropharmacol_46_95 |
| PubMedID: 14654101 |
| Title : Interaction of a new potent anticholinesterasic compound (+\/-)huprine X with muscarinic receptors in rat brain - Roman_2002_Neurosci.Lett_325_103 |
| Author(s) : Roman S , Vivas NM , Badia A , Clos MV |
| Ref : Neuroscience Letters , 325 :103 , 2002 |
| Abstract : |
| PubMedSearch : Roman_2002_Neurosci.Lett_325_103 |
| PubMedID: 12044632 |
| Title : Role of calcium on the modulation of spontaneous acetylcholine efflux by the D2 dopamine receptor subtype in rat striatal synaptosomes - Sanz_2000_Brain.Res_854_42 |
| Author(s) : Sanz AG , Badia A , Clos MV |
| Ref : Brain Research , 854 :42 , 2000 |
| Abstract : |
| PubMedSearch : Sanz_2000_Brain.Res_854_42 |
| PubMedID: 10784105 |
| Title : Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases beta-adrenoceptor-linked cyclic AMP formation in middle-aged rats - Dierssen_1992_Brain.Res_586_117 |
| Author(s) : Dierssen M , Marmol F , Vivas NM , Clos MV , Badia A |
| Ref : Brain Research , 586 :117 , 1992 |
| Abstract : |
| PubMedSearch : Dierssen_1992_Brain.Res_586_117 |
| PubMedID: 1380875 |
| Title : Acute effects of tetrahydroaminoacridine on beta-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats - Dierssen_1991_Neurosci.Lett_132_51 |
| Author(s) : Dierssen M , Marmol F , Vivas NM , Clos MV , Gascon S , Badia A |
| Ref : Neuroscience Letters , 132 :51 , 1991 |
| Abstract : |
| PubMedSearch : Dierssen_1991_Neurosci.Lett_132_51 |
| PubMedID: 1724070 |