7AMZ

Name : Human butyrylcholinesterase in complexe with N-((2S,3R)-3-hydr oxy-4-(neopentylamino)-1-phenylbutan-2-yl)-2,2-diphenylacetamide (51)

Revelation date : 26-May-2021

Family : BCHE

Gene_locus : human-BCHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment

Ligand :

References (1)

Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397
Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021
PubMedID: 33838585

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 7AMZ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7AMZ Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7AMZ Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7AMZ 3D, interactive encyclopedia of proteins - PROTEOPEDIA server