Report for Hofner G

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References (8)

Title : Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies - Panek_2023_Eur.J.Med.Chem_249_115135
Author(s) : Panek D , Pasieka A , Latacz G , Zareba P , Szczech M , Godyn J , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Walczak M , Smolik M , Salat K , Hofner G , Wanner K , Wieckowska A , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 249 :115135 , 2023
Abstract : Panek_2023_Eur.J.Med.Chem_249_115135
ESTHER : Panek_2023_Eur.J.Med.Chem_249_115135
PubMedSearch : Panek_2023_Eur.J.Med.Chem_249_115135
PubMedID: 36696766
Gene_locus related to this paper: human-BCHE

Title : A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment - Kaiser_2022_Toxicol.Lett_373_160
Author(s) : Kaiser J , Gertzen CGW , Bernauer T , Hofner G , Niessen KV , Seeger T , Paintner FF , Wanner KT , Worek F , Thiermann H , Gohlke H
Ref : Toxicol Lett , 373 :160 , 2022
Abstract : Kaiser_2022_Toxicol.Lett_373_160
ESTHER : Kaiser_2022_Toxicol.Lett_373_160
PubMedSearch : Kaiser_2022_Toxicol.Lett_373_160
PubMedID: 36503818

Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397
Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021
Abstract : Pasieka_2021_Eur.J.Med.Chem_218_113397
ESTHER : Pasieka_2021_Eur.J.Med.Chem_218_113397
PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397
PubMedID: 33838585

Title : Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor - Wein_2018_Toxicol.Lett_293_184
Author(s) : Wein T , Hofner G , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H , Wanner KT
Ref : Toxicol Lett , 293 :184 , 2018
Abstract : Wein_2018_Toxicol.Lett_293_184
ESTHER : Wein_2018_Toxicol.Lett_293_184
PubMedSearch : Wein_2018_Toxicol.Lett_293_184
PubMedID: 29097222

Title : Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_2653
Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT
Ref : ChemMedChem , 13 :2653 , 2018
Abstract : Rappengluck_2018_ChemMedChem_13_2653
ESTHER : Rappengluck_2018_ChemMedChem_13_2653
PubMedSearch : Rappengluck_2018_ChemMedChem_13_2653
PubMedID: 30362667

Title : Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_1806
Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT
Ref : ChemMedChem , 13 :1806 , 2018
Abstract : Rappengluck_2018_ChemMedChem_13_1806
ESTHER : Rappengluck_2018_ChemMedChem_13_1806
PubMedSearch : Rappengluck_2018_ChemMedChem_13_1806
PubMedID: 29974635

Title : In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers - Niessen_2018_Toxicol.Lett_293_190
Author(s) : Niessen KV , Seeger T , Rappengluck S , Wein T , Hofner G , Wanner KT , Thiermann H , Worek F
Ref : Toxicol Lett , 293 :190 , 2018
Abstract : Niessen_2018_Toxicol.Lett_293_190
ESTHER : Niessen_2018_Toxicol.Lett_293_190
PubMedSearch : Niessen_2018_Toxicol.Lett_293_190
PubMedID: 29024789

Title : Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor - Sichler_2018_Toxicol.Lett_293_172
Author(s) : Sichler S , Hofner G , Rappengluck S , Wein T , Niessen KV , Seeger T , Worek F , Thiermann H , Paintner FF , Wanner KT
Ref : Toxicol Lett , 293 :172 , 2018
Abstract : Sichler_2018_Toxicol.Lett_293_172
ESTHER : Sichler_2018_Toxicol.Lett_293_172
PubMedSearch : Sichler_2018_Toxicol.Lett_293_172
PubMedID: 29146291