| Title : MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor - Nitsche_2024_Toxicol.Lett_392_94 |
| Author(s) : Nitsche V , Hofner G , Kaiser J , Gertzen CGW , Seeger T , Niessen KV , Steinritz D , Worek F , Gohlke H , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 392 :94 , 2024 |
| Abstract : |
| PubMedSearch : Nitsche_2024_Toxicol.Lett_392_94 |
| PubMedID: 38216073 |
| Title : Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor - Sichler_2024_Toxicol.Lett_394_23 |
| Author(s) : Sichler S , Hofner G , Nitsche V , Niessen KV , Seeger T , Worek F , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 394 :23 , 2024 |
| Abstract : |
| PubMedSearch : Sichler_2024_Toxicol.Lett_394_23 |
| PubMedID: 38387764 |
| Title : Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents - Bernauer_2024_Toxicol.Lett__ |
| Author(s) : Bernauer T , Nitsche V , Kaiser J , Gertzen CGW , Hofner G , Niessen KV , Seeger T , Steinritz D , Worek F , Gohlke H , Wanner KT , Paintner FF |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Bernauer_2024_Toxicol.Lett__ |
| PubMedID: 38759939 |
| Title : A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment - Kaiser_2023_Toxicol.Lett_373_160 |
| Author(s) : Kaiser J , Gertzen CGW , Bernauer T , Hofner G , Niessen KV , Seeger T , Paintner FF , Wanner KT , Worek F , Thiermann H , Gohlke H |
| Ref : Toxicol Lett , 373 :160 , 2023 |
| Abstract : |
| PubMedSearch : Kaiser_2023_Toxicol.Lett_373_160 |
| PubMedID: 36503818 |
| Title : Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies - Panek_2023_Eur.J.Med.Chem_249_115135 |
| Author(s) : Panek D , Pasieka A , Latacz G , Zareba P , Szczech M , Godyn J , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Walczak M , Smolik M , Salat K , Hofner G , Wanner K , Wieckowska A , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 249 :115135 , 2023 |
| Abstract : |
| PubMedSearch : Panek_2023_Eur.J.Med.Chem_249_115135 |
| PubMedID: 36696766 |
| Gene_locus related to this paper: human-BCHE |
| Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021 |
| Abstract : |
| PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedID: 33838585 |
| Title : Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_1806 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :1806 , 2018 |
| Abstract : |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_1806 |
| PubMedID: 29974635 |
| Title : In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers - Niessen_2018_Toxicol.Lett_293_190 |
| Author(s) : Niessen KV , Seeger T , Rappengluck S , Wein T , Hofner G , Wanner KT , Thiermann H , Worek F |
| Ref : Toxicol Lett , 293 :190 , 2018 |
| Abstract : |
| PubMedSearch : Niessen_2018_Toxicol.Lett_293_190 |
| PubMedID: 29024789 |
| Title : Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor - Sichler_2018_Toxicol.Lett_293_172 |
| Author(s) : Sichler S , Hofner G , Rappengluck S , Wein T , Niessen KV , Seeger T , Worek F , Thiermann H , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 293 :172 , 2018 |
| Abstract : |
| PubMedSearch : Sichler_2018_Toxicol.Lett_293_172 |
| PubMedID: 29146291 |
| Title : Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor - Wein_2018_Toxicol.Lett_293_184 |
| Author(s) : Wein T , Hofner G , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H , Wanner KT |
| Ref : Toxicol Lett , 293 :184 , 2018 |
| Abstract : |
| PubMedSearch : Wein_2018_Toxicol.Lett_293_184 |
| PubMedID: 29097222 |
| Title : Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_2653 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :2653 , 2018 |
| Abstract : |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_2653 |
| PubMedID: 30362667 |