Report for Jonczyk J

General

Full name : Jonczyk Jakub

First name : Jakub

Mail : Department of Physicochemical Drug Analysis, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Cracow, Medyczna 9

Zip Code :

City :

Country : Poland

Email :

Phone :

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References (23)

Title : New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease - Czarnecka_2023_J.Enzyme.Inhib.Med.Chem_38_2158822
Author(s) : Czarnecka K , Girek M , Krecisz P , Skibinski R , Latka K , Jonczyk J , Bajda M , Szymczyk P , Galita G , Kabzinski J , Majsterek I , Espargaro A , Sabate R , Szymanski P
Ref : J Enzyme Inhib Med Chem , 38 :2158822 , 2023
Abstract : Czarnecka_2023_J.Enzyme.Inhib.Med.Chem_38_2158822
ESTHER : Czarnecka_2023_J.Enzyme.Inhib.Med.Chem_38_2158822
PubMedSearch : Czarnecka_2023_J.Enzyme.Inhib.Med.Chem_38_2158822
PubMedID: 36629422

Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397
Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021
Abstract : Pasieka_2021_Eur.J.Med.Chem_218_113397
ESTHER : Pasieka_2021_Eur.J.Med.Chem_218_113397
PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397
PubMedID: 33838585

Title : Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase - Jonczyk_2021_Biomolecules_11_
Author(s) : Jonczyk J , Kukulowicz J , Aatka K , Malawska B , Jung YS , Musilek K , Bajda M
Ref : Biomolecules , 11 : , 2021
Abstract : Jonczyk_2021_Biomolecules_11_
ESTHER : Jonczyk_2021_Biomolecules_11_
PubMedSearch : Jonczyk_2021_Biomolecules_11_
PubMedID: 33513955

Title : Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates - Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437
Author(s) : Lee HM , Andrys R , Jonczyk J , Kim K , Vishakantegowda AG , Malinak D , Skarka A , Schmidt M , Vaskova M , Latka K , Bajda M , Jung YS , Malawska B , Musilek K
Ref : J Enzyme Inhib Med Chem , 36 :437 , 2021
Abstract : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437
ESTHER : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437
PubMedSearch : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437
PubMedID: 33467931

Title : New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease - Czarnecka_2020_Int.J.Mol.Sci_21_
Author(s) : Czarnecka K , Girek M , Wojtowicz P , Krecisz P , Skibinski R , Jonczyk J , Latka K , Bajda M , Walczak A , Galita G , Kabzinski J , Majsterek I , Szymczyk P , Szymanski P
Ref : Int J Mol Sci , 21 : , 2020
Abstract : Czarnecka_2020_Int.J.Mol.Sci_21_
ESTHER : Czarnecka_2020_Int.J.Mol.Sci_21_
PubMedSearch : Czarnecka_2020_Int.J.Mol.Sci_21_
PubMedID: 32466601

Title : Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity - Jonczyk_2020_Molecules_25_
Author(s) : Jonczyk J , Godyn J , Stawarska E , Morak-Mlodawska B , Jelen M , Pluta K , Malawska B
Ref : Molecules , 25 : , 2020
Abstract : Jonczyk_2020_Molecules_25_
ESTHER : Jonczyk_2020_Molecules_25_
PubMedSearch : Jonczyk_2020_Molecules_25_
PubMedID: 32503288

Title : Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease - Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944
Author(s) : Szalaj N , Godyn J , Jonczyk J , Pasieka A , Panek D , Wichur T , Wieckowski K , Zareba P , Bajda M , Pislar A , Malawska B , Sabate R , Wieckowska A
Ref : J Enzyme Inhib Med Chem , 35 :1944 , 2020
Abstract : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944
ESTHER : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944
PubMedSearch : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944
PubMedID: 33092411

Title : 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease - Wichur_2019_Eur.J.Med.Chem_187_111916
Author(s) : Wichur T , Wieckowska A , Wieckowski K , Godyn J , Jonczyk J , Valdivieso ADR , Panek D , Pasieka A , Sabate R , Knez D , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 187 :111916 , 2019
Abstract : Wichur_2019_Eur.J.Med.Chem_187_111916
ESTHER : Wichur_2019_Eur.J.Med.Chem_187_111916
PubMedSearch : Wichur_2019_Eur.J.Med.Chem_187_111916
PubMedID: 31812794

Title : Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives - Jonczyk_2019_Bioorg.Chem_90_103084
Author(s) : Jonczyk J , Lodarski K , Staszewski M , Godyn J , Zareba P , Soukup O , Janockova J , Korabecny J , Salat K , Malikowska-Racia N , Hebda M , Szalaj N , Filipek B , Walczynski K , Malawska B , Bajda M
Ref : Bioorg Chem , 90 :103084 , 2019
Abstract : Jonczyk_2019_Bioorg.Chem_90_103084
ESTHER : Jonczyk_2019_Bioorg.Chem_90_103084
PubMedSearch : Jonczyk_2019_Bioorg.Chem_90_103084
PubMedID: 31271942

Title : Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's Disease - Czarnecka_2019_Int.J.Mol.Sci_20_
Author(s) : Czarnecka K , Girek M , Krecisz P , Skibinski R , Latka K , Jonczyk J , Bajda M , Kabzinski J , Majsterek I , Szymczyk P , Szymanski P
Ref : Int J Mol Sci , 20 : , 2019
Abstract : Czarnecka_2019_Int.J.Mol.Sci_20_
ESTHER : Czarnecka_2019_Int.J.Mol.Sci_20_
PubMedSearch : Czarnecka_2019_Int.J.Mol.Sci_20_
PubMedID: 30678364

Title : Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents - Panek_2018_ACS.Chem.Neurosci_9_1074
Author(s) : Panek D , Wieckowska A , Jonczyk J , Godyn J , Bajda M , Wichur T , Pasieka A , Knez D , Pislar A , Korabecny J , Soukup O , Sepsova V , Sabate R , Kos J , Gobec S , Malawska B
Ref : ACS Chem Neurosci , 9 :1074 , 2018
Abstract : Panek_2018_ACS.Chem.Neurosci_9_1074
ESTHER : Panek_2018_ACS.Chem.Neurosci_9_1074
PubMedSearch : Panek_2018_ACS.Chem.Neurosci_9_1074
PubMedID: 29345897

Title : Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents - Panek_2018_Molecules_23_
Author(s) : Panek D , Wieckowska A , Pasieka A , Godyn J , Jonczyk J , Bajda M , Knez D , Gobec S , Malawska B
Ref : Molecules , 23 : , 2018
Abstract : Panek_2018_Molecules_23_
ESTHER : Panek_2018_Molecules_23_
PubMedSearch : Panek_2018_Molecules_23_
PubMedID: 29414887

Title : Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment - Czarnecka_2018_Eur.J.Med.Chem_145_760
Author(s) : Czarnecka K , Chufarova N , Halczuk K , Maciejewska K , Girek M , Skibinski R , Jonczyk J , Bajda M , Kabzinski J , Majsterek I , Szymanski P
Ref : Eur Journal of Medicinal Chemistry , 145 :760 , 2018
Abstract : Czarnecka_2018_Eur.J.Med.Chem_145_760
ESTHER : Czarnecka_2018_Eur.J.Med.Chem_145_760
PubMedSearch : Czarnecka_2018_Eur.J.Med.Chem_145_760
PubMedID: 29353726

Title : Novel carbamate derivatives as selective butyrylcholinesterase inhibitors - Bajda_2018_Bioorg.Chem_78_29
Author(s) : Bajda M , Latka K , Hebda M , Jonczyk J , Malawska B
Ref : Bioorg Chem , 78 :29 , 2018
Abstract : Bajda_2018_Bioorg.Chem_78_29
ESTHER : Bajda_2018_Bioorg.Chem_78_29
PubMedSearch : Bajda_2018_Bioorg.Chem_78_29
PubMedID: 29529519

Title : New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer's disease - Czarnecka_2017_J.Enzyme.Inhib.Med.Chem_33_158
Author(s) : Czarnecka K , Girek M , Maciejewska K , Skibinski R , Jonczyk J , Bajda M , Kabzinski J , Solowiej P , Majsterek I , Szymanski P
Ref : J Enzyme Inhib Med Chem , 33 :158 , 2017
Abstract : Czarnecka_2017_J.Enzyme.Inhib.Med.Chem_33_158
ESTHER : Czarnecka_2017_J.Enzyme.Inhib.Med.Chem_33_158
PubMedSearch : Czarnecka_2017_J.Enzyme.Inhib.Med.Chem_33_158
PubMedID: 29210299

Title : Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment - Czarnecka_2017_Bioorg.Chem_72_315
Author(s) : Czarnecka K , Szymanski P , Girek M , Mikiciuk-Olasik E , Skibinski R , Kabzinski J , Majsterek I , Malawska B , Jonczyk J , Bajda M
Ref : Bioorg Chem , 72 :315 , 2017
Abstract : Czarnecka_2017_Bioorg.Chem_72_315
ESTHER : Czarnecka_2017_Bioorg.Chem_72_315
PubMedSearch : Czarnecka_2017_Bioorg.Chem_72_315
PubMedID: 28501648

Title : Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation - Panek_2016_Eur.J.Med.Chem_125_676
Author(s) : Panek D , Wieckowska A , Wichur T , Bajda M , Godyn J , Jonczyk J , Mika K , Janockova J , Soukup O , Knez D , Korabecny J , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 125 :676 , 2016
Abstract : Panek_2016_Eur.J.Med.Chem_125_676
ESTHER : Panek_2016_Eur.J.Med.Chem_125_676
PubMedSearch : Panek_2016_Eur.J.Med.Chem_125_676
PubMedID: 27721153

Title : Therapeutic strategies for Alzheimer's disease in clinical trials - Godyn_2016_Pharmacol.Rep_68_127
Author(s) : Godyn J , Jonczyk J , Panek D , Malawska B
Ref : Pharmacol Rep , 68 :127 , 2016
Abstract : Godyn_2016_Pharmacol.Rep_68_127
ESTHER : Godyn_2016_Pharmacol.Rep_68_127
PubMedSearch : Godyn_2016_Pharmacol.Rep_68_127
PubMedID: 26721364

Title : Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands - Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
Author(s) : Lazewska D , Jonczyk J , Bajda M , Szalaj N , Wieckowska A , Panek D , Moore C , Kuder K , Malawska B , Kiec-Kononowicz K
Ref : Bioorganic & Medicinal Chemistry Lett , 26 :4140 , 2016
Abstract : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
ESTHER : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
PubMedSearch : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
PubMedID: 27445168

Title : Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines - Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98
Author(s) : Lodarski K , Jonczyk J , Guzior N , Bajda M , Gladysz J , Walczyk J , Jelen M , Morak-Mlodawska B , Pluta K , Malawska B
Ref : J Enzyme Inhib Med Chem , 30 :98 , 2015
Abstract : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98
ESTHER : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98
PubMedSearch : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98
PubMedID: 24666296

Title : Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease - Bajda_2015_Bioorg.Med.Chem_23_5610
Author(s) : Bajda M , Jonczyk J , Malawska B , Czarnecka K , Girek M , Olszewska P , Sikora J , Mikiciuk-Olasik E , Skibinski R , Gumieniczek A , Szymanski P
Ref : Bioorganic & Medicinal Chemistry , 23 :5610 , 2015
Abstract : Bajda_2015_Bioorg.Med.Chem_23_5610
ESTHER : Bajda_2015_Bioorg.Med.Chem_23_5610
PubMedSearch : Bajda_2015_Bioorg.Med.Chem_23_5610
PubMedID: 26242241

Title : Novel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studies - Mutahir_2015_Bioorg.Chem_64_13
Author(s) : Mutahir S , Jonczyk J , Bajda M , Khan IU , Khan MA , Ullah N , Ashraf M , Qurat Ul A , Riaz S , Hussain S , Yar M
Ref : Bioorg Chem , 64 :13 , 2015
Abstract : Mutahir_2015_Bioorg.Chem_64_13
ESTHER : Mutahir_2015_Bioorg.Chem_64_13
PubMedSearch : Mutahir_2015_Bioorg.Chem_64_13
PubMedID: 26595185

Title : New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis - Szymanski_2013_Molecules_18_2878
Author(s) : Szymanski P , Skibinski R , Inglot T , Bajda M , Jonczyk J , Malawska B , Mikiciuk-Olasik E
Ref : Molecules , 18 :2878 , 2013
Abstract : Szymanski_2013_Molecules_18_2878
ESTHER : Szymanski_2013_Molecules_18_2878
PubMedSearch : Szymanski_2013_Molecules_18_2878
PubMedID: 23459299