7Q1P

Name : Crystal structure of human butyrylcholinesterase in complex with N-[(2R)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-3,3-diphenylpropanamide

Revelation date : 16-Nov-2022

Family : BCHE

Gene_locus : human-BCHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Brazzolotto, X.,Panek, D.,Pasieka, A.,Malawska, B.,Nachon, F.

Ligand :

References (1)

Title : Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies - Panek_2023_Eur.J.Med.Chem_249_115135
Author(s) : Panek D , Pasieka A , Latacz G , Zareba P , Szczech M , Godyn J , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Walczak M , Smolik M , Salat K , Hofner G , Wanner K , Wieckowska A , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 249 :115135 , 2023
PubMedID: 36696766
Gene_locus related to this paper: human-BCHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 7Q1P Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7Q1P Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7Q1P Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7Q1P 3D, interactive encyclopedia of proteins - PROTEOPEDIA server