9F1A
Name : Crystal structure of human soluble epoxide hydrolase C-terminal domain in complex with a benzohomoadamantane-based urea inhibitor UB-BJ-05
Revelation date : 30-Apr-2025
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Qiu, Q., Prischi, F., Conte, M.R., Jora, B., Vazquez, S.
References (3)
| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9F1A Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9F1A Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9F1A Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9F1A 3D, interactive encyclopedia of proteins - PROTEOPEDIA server