9F8D
Name : Crystal structure of human monoacylglycerol lipase in complex with compound 7i SCHEMBL22491361
Revelation date : 22-Jan-2025
Family : Monoglyceridelipase_lysophospholip
Gene_locus : human-MGLL
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Kuhn, B.,Ritter, M.,Hornsperger, B.,Bell, C.,Kocer, B.,Rombach, D.,Richter, H.,Grether, U.,Gobbi, L.,Kuratli, M.,Collin, L.,Benz, J.
Ligand : Inhibitor SCHEMBL22491361 Ligand in structure: Ligplot
References (1)
| Title : Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors - Kuhn_2024_J.Med.Chem__ |
| Author(s) : Kuhn B , Ritter M , Hornsperger B , Bell C , Kocer B , Rombach D , Lutz MDR , Gobbi L , Kuratli M , Bartelmus C , Burkler M , Koller R , Tosatti P , Ruf I , Guerard M , Pavlovic A , Stephanus J , O'Hara F , Wetzl D , Saal W , Stihle M , Roth D , Hug M , Huber S , Heer D , Kroll C , Topp A , Schneider M , Gertsch J , Glasmacher S , van der Stelt M , Martella A , Wittwer MB , Collin L , Benz J , Richter H , Grether U |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Kuhn_2024_J.Med.Chem__ |
| PubMedID: 39360636 |
| Gene_locus related to this paper: human-MGLL |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9F8D Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9F8D Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9F8D Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9F8D 3D, interactive encyclopedia of proteins - PROTEOPEDIA server