Ruf I

References (5)

Title : Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors - Kuhn_2024_J.Med.Chem__
Author(s) : Kuhn B , Ritter M , Hornsperger B , Bell C , Kocer B , Rombach D , Lutz MDR , Gobbi L , Kuratli M , Bartelmus C , Burkler M , Koller R , Tosatti P , Ruf I , Guerard M , Pavlovic A , Stephanus J , O'Hara F , Wetzl D , Saal W , Stihle M , Roth D , Hug M , Huber S , Heer D , Kroll C , Topp A , Schneider M , Gertsch J , Glasmacher S , van der Stelt M , Martella A , Wittwer MB , Collin L , Benz J , Richter H , Grether U
Ref : Journal of Medicinal Chemistry , : , 2024
Abstract :
PubMedSearch : Kuhn_2024_J.Med.Chem__
PubMedID: 39360636
Gene_locus related to this paper: human-MGLL

Title : Pharmacological blockade of 2-AG degradation ameliorates clinical, neuroinflammatory and synaptic alterations in experimental autoimmune encephalomyelitis - Guadalupi_2024_Neuropharmacol__109940
Author(s) : Guadalupi L , Mandolesi G , Vanni V , Balletta S , Caioli S , Pavlovic A , De Vito F , Fresegna D , Sanna K , Vitiello L , Nencini M , Tartacca A , Mariani F , Rovella V , Schippling S , Ruf I , Collin L , Centonze D , Musella A
Ref : Neuropharmacology , :109940 , 2024
Abstract :
PubMedSearch : Guadalupi_2024_Neuropharmacol__109940
PubMedID: 38570068
Gene_locus related to this paper: human-ABHD6

Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039
Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M
Ref : Nat Commun , 14 :8039 , 2023
Abstract :
PubMedSearch : Jiang_2023_Nat.Commun_14_8039
PubMedID: 38052772

Title : A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature - Kemble_2022_PLoS.One_17_e0268590
Author(s) : Kemble AM , Hornsperger B , Ruf I , Richter H , Benz J , Kuhn B , Heer D , Wittwer M , Engelhardt B , Grether U , Collin L
Ref : PLoS ONE , 17 :e0268590 , 2022
Abstract :
PubMedSearch : Kemble_2022_PLoS.One_17_e0268590
PubMedID: 36084029
Gene_locus related to this paper: human-MGLL

Title : Reconstruction of evolutionary changes in fat and toxin consumption reveals associations with gene losses in mammals: a case study for the lipase inhibitor PNLIPRP1 and the xenobiotic receptor NR1I3 - Wagner_2021_J.Evol.Biol__
Author(s) : Wagner F , Ruf I , Lehmann T , Hofmann R , Ortmann S , Schiffmann C , Hiller M , Stefen C , Stuckas H
Ref : J Evol Biol , : , 2021
Abstract :
PubMedSearch : Wagner_2021_J.Evol.Biol__
PubMedID: 34882899