| Title : Exploration of (R)-[(11)C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates - He_2024_Eur.J.Nucl.Med.Mol.Imaging__ |
| Author(s) : He Y , Zheng M , Gu J , Reichert L , Trimborn J , Zhang H , Keller C , Crosby M , Collin L , Heer D , Pavlovic A , Topp A , Wittwer MB , Grether U , Gobbi L , Schibli R , Huang Y , Mu L |
| Ref : Eur J Nucl Med Mol Imaging , : , 2024 |
| Abstract : |
| PubMedSearch : He_2024_Eur.J.Nucl.Med.Mol.Imaging__ |
| PubMedID: 39673602 |
| Title : Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors - Kuhn_2024_J.Med.Chem__ |
| Author(s) : Kuhn B , Ritter M , Hornsperger B , Bell C , Kocer B , Rombach D , Lutz MDR , Gobbi L , Kuratli M , Bartelmus C , Burkler M , Koller R , Tosatti P , Ruf I , Guerard M , Pavlovic A , Stephanus J , O'Hara F , Wetzl D , Saal W , Stihle M , Roth D , Hug M , Huber S , Heer D , Kroll C , Topp A , Schneider M , Gertsch J , Glasmacher S , van der Stelt M , Martella A , Wittwer MB , Collin L , Benz J , Richter H , Grether U |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Kuhn_2024_J.Med.Chem__ |
| PubMedID: 39360636 |
| Gene_locus related to this paper: human-MGLL |
| Title : Pharmacological blockade of 2-AG degradation ameliorates clinical, neuroinflammatory and synaptic alterations in experimental autoimmune encephalomyelitis - Guadalupi_2024_Neuropharmacol__109940 |
| Author(s) : Guadalupi L , Mandolesi G , Vanni V , Balletta S , Caioli S , Pavlovic A , De Vito F , Fresegna D , Sanna K , Vitiello L , Nencini M , Tartacca A , Mariani F , Rovella V , Schippling S , Ruf I , Collin L , Centonze D , Musella A |
| Ref : Neuropharmacology , :109940 , 2024 |
| Abstract : |
| PubMedSearch : Guadalupi_2024_Neuropharmacol__109940 |
| PubMedID: 38570068 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039 |
| Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M |
| Ref : Nat Commun , 14 :8039 , 2023 |
| Abstract : |
| PubMedSearch : Jiang_2023_Nat.Commun_14_8039 |
| PubMedID: 38052772 |
| Title : Identification of (R)-[(18)F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development - He_2023_J.Nucl.Med__ |
| Author(s) : He Y , Kramer SD , Grether U , Wittwer MB , Collin L , Kuhn B , Topp A , Heer D , O'Hara F , Honer M , Pavlovic A , Richter H , Ritter M , Rombach D , Keller C , Gobbi L , Mu L |
| Ref : J Nucl Med , : , 2023 |
| Abstract : |
| PubMedSearch : He_2023_J.Nucl.Med__ |
| PubMedID: 38164615 |