9FY5

Name : Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL23211786

Revelation date : 11-Dec-2024

Family : Monoglyceridelipase_lysophospholip

Gene_locus : human-MGLL

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Gazzi, T.,Grether, U.,Nazare, M.,Hochstrasser, R.,Wang, H.,Heer, D.,Topp, A.,Benz, J.

Ligand : Inhibitor SCHEMBL23211786 Ligand in structure: Ligplot

References (1)

Title : Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells - Gazzi_2024_Chembiochem__e202400704
Author(s) : Gazzi T , Brennecke B , Olikauskas V , Hochstrasser R , Wang H , Keen Chao S , Atz K , Mostinski Y , Topp A , Heer D , Kaufmann I , Ritter M , Gobbi L , Hornsperger B , Wagner B , Richter H , O'Hara F , Wittwer MB , Jul Hansen D , Collin L , Kuhn B , Benz J , Grether U , Nazare M
Ref : Chembiochem , :e202400704 , 2024
Abstract :
PubMedSearch : Gazzi_2024_Chembiochem__e202400704
PubMedID: 39607084
Gene_locus related to this paper: human-MGLL

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 9FY5 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 9FY5 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 9FY5 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 9FY5 3D, interactive encyclopedia of proteins - PROTEOPEDIA server