| Title : Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimization - Nippa_2025_Nat.Commun__ |
| Author(s) : Nippa DF , Atz K , Stenzhorn Y , Muller AT , Tosstorff A , Benz J , Binch H , Burkler M , Haider A , Heer D , Hochstrasser R , Kramer C , Reutlinger M , Schneider P , Shema T , Topp A , Walter A , Wittwer MB , Wolfard J , Kuhn B , van der Stelt M , Martin RE , Grether U , Schneider G |
| Ref : Nat Commun , : , 2025 |
| Abstract : |
| PubMedSearch : Nippa_2025_Nat.Commun__ |
| PubMedID: 41290653 |
| Gene_locus related to this paper: human-MGLL |
| Title : Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimization - Nippa_2025_Nat.Commun__ |
| Author(s) : Nippa DF , Atz K , Stenzhorn Y , Muller AT , Tosstorff A , Benz J , Binch H , Burkler M , Haider A , Heer D , Hochstrasser R , Kramer C , Reutlinger M , Schneider P , Shema T , Topp A , Walter A , Wittwer MB , Wolfard J , Kuhn B , van der Stelt M , Martin RE , Grether U , Schneider G |
| Ref : Nat Commun , : , 2025 |
| Abstract : |
| PubMedSearch : Nippa_2025_Nat.Commun__ |
| PubMedID: 41290653 |
| Gene_locus related to this paper: human-MGLL |
| Title : Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimization - Nippa_2025_Nat.Commun__ |
| Author(s) : Nippa DF , Atz K , Stenzhorn Y , Muller AT , Tosstorff A , Benz J , Binch H , Burkler M , Haider A , Heer D , Hochstrasser R , Kramer C , Reutlinger M , Schneider P , Shema T , Topp A , Walter A , Wittwer MB , Wolfard J , Kuhn B , van der Stelt M , Martin RE , Grether U , Schneider G |
| Ref : Nat Commun , : , 2025 |
| Abstract : |
| PubMedSearch : Nippa_2025_Nat.Commun__ |
| PubMedID: 41290653 |
| Gene_locus related to this paper: human-MGLL |
| Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
| Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
| Ref : Chimia (Aarau) , 78 :499 , 2024 |
| Abstract : |
| PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
| PubMedID: 39221845 |
| Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
| Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
| Ref : Chimia (Aarau) , 78 :499 , 2024 |
| Abstract : |
| PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
| PubMedID: 39221845 |
| Title : Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells - Gazzi_2024_Chembiochem__e202400704 |
| Author(s) : Gazzi T , Brennecke B , Olikauskas V , Hochstrasser R , Wang H , Keen Chao S , Atz K , Mostinski Y , Topp A , Heer D , Kaufmann I , Ritter M , Gobbi L , Hornsperger B , Wagner B , Richter H , O'Hara F , Wittwer MB , Jul Hansen D , Collin L , Kuhn B , Benz J , Grether U , Nazare M |
| Ref : Chembiochem , :e202400704 , 2024 |
| Abstract : |
| PubMedSearch : Gazzi_2024_Chembiochem__e202400704 |
| PubMedID: 39607084 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells - Gazzi_2024_Chembiochem__e202400704 |
| Author(s) : Gazzi T , Brennecke B , Olikauskas V , Hochstrasser R , Wang H , Keen Chao S , Atz K , Mostinski Y , Topp A , Heer D , Kaufmann I , Ritter M , Gobbi L , Hornsperger B , Wagner B , Richter H , O'Hara F , Wittwer MB , Jul Hansen D , Collin L , Kuhn B , Benz J , Grether U , Nazare M |
| Ref : Chembiochem , :e202400704 , 2024 |
| Abstract : |
| PubMedSearch : Gazzi_2024_Chembiochem__e202400704 |
| PubMedID: 39607084 |
| Gene_locus related to this paper: human-MGLL |
| Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
| Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
| Ref : Chimia (Aarau) , 78 :499 , 2024 |
| Abstract : |
| PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
| PubMedID: 39221845 |
| Title : Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells - Gazzi_2024_Chembiochem__e202400704 |
| Author(s) : Gazzi T , Brennecke B , Olikauskas V , Hochstrasser R , Wang H , Keen Chao S , Atz K , Mostinski Y , Topp A , Heer D , Kaufmann I , Ritter M , Gobbi L , Hornsperger B , Wagner B , Richter H , O'Hara F , Wittwer MB , Jul Hansen D , Collin L , Kuhn B , Benz J , Grether U , Nazare M |
| Ref : Chembiochem , :e202400704 , 2024 |
| Abstract : |
| PubMedSearch : Gazzi_2024_Chembiochem__e202400704 |
| PubMedID: 39607084 |
| Gene_locus related to this paper: human-MGLL |