9R9E
Name : Human Butyrylcholinesterase in complex with N-(3-methoxypropyl)-N-((1-(prop-2-yn-1-yl)pyrrolidin-3-yl)methyl)naphthalene-2-sulfonamide N-Propargylpyrrolidine-based compound 10
Revelation date : 13-Aug-2025
Family : BCHE
Gene_locus : human-BCHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Ligand : Inhibitor N-Propargylpyrrolidine-based-Cpd10 Ligand in structure: Ligplot
References (3)
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9R9E Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9R9E Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9R9E Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9R9E 3D, interactive encyclopedia of proteins - PROTEOPEDIA server