9RGC
Name : Recombinant Human Butyrylcholinesterase in complex with LP1488 (7-[(4-{[(3,4-dimethoxybenzyl)(methyl)amino]methyl}benzyl)oxy]-4-(hydroxymethyl)-2H-chromen-2-one)
Revelation date : 27-May-2026
Family : BCHE
Gene_locus : human-BCHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Brazzolotto, X., Pisani, L.
References (1)
| Title : Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961 |
| Author(s) : Rullo M , La Spada G , Brazzolotto X , Marchese S , El Idrissi IG , Miciaccia M , Colella M , Brea JM , Macchia E , Loza MI , Gottinger A , Scilimati A , Perrone MG , Stefanachi A , Binda C , Leonetti F , Pisani L |
| Ref : European Journal of Medicinal Chemistry , :118961 , 2026 |
| Abstract : |
| PubMedSearch : Rullo_2026_Eur.J.Med.Chem_316_118961 |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9RGC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9RGC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9RGC Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9RGC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server