3-hydroxybutyrate

General

Type : Butyrate

Chemical_Nomenclature :

Canonical SMILES : CC(CC(=O)[O-])O || CC(CC(=O)O)O

InChI : InChI=1S\/C4H8O3\/c1-3(5)2-4(6)7\/h3,5H,2H2,1H3,(H,6,7)\/p-1 || InChI=1S\/C4H8O3\/c1-3(5)2-4(6)7\/h3,5H,2H2,1H3,(H,6,7)

InChIKey : WHBMMWSBFZVSSR-UHFFFAOYSA-M || WHBMMWSBFZVSSR-UHFFFAOYSA-N

Other name(s) : 3HB  ||  3-hydroxybutyrate  ||  3-hydroxybutanoate  ||  beta-hydroxybutyrate  ||  beta-hydroxybutanoate  ||  R-3HB  ||  FG2UN5EP9V  ||  3-hydroxybutyric acid  ||  3-hydroxybutanoic acid  ||  Butanoic acid, 3-hydroxy-


MW : 103.10

Formula : C4H7O3-

CAS_number : 300-85-6,    625-71-8

PubChem : 3541112,    441

UniChem : WHBMMWSBFZVSSR-UHFFFAOYSA-M,    WHBMMWSBFZVSSR-UHFFFAOYSA-N

Target

Structures : No structure

Families : PHA_synth_I, PHA_synth_III_C, PHA_synth_II

References (15)

Title : A review on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] and genetic modifications that affect its production - Tang_2022_Front.Bioeng.Biotechnol_10_1057067
Author(s) : Tang HJ , Neoh SZ , Sudesh K
Ref : Front Bioeng Biotechnol , 10 :1057067 , 2022
Abstract :
PubMedSearch : Tang_2022_Front.Bioeng.Biotechnol_10_1057067
PubMedID: 36545679

Title : Engineering Pseudomonas entomophila for synthesis of copolymers with defined fractions of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoates - Li_2019_Metab.Eng_52_253
Author(s) : Li M , Chen X , Che X , Zhang H , Wu LP , Du H , Chen GQ
Ref : Metab Eng , 52 :253 , 2019
Abstract :
PubMedSearch : Li_2019_Metab.Eng_52_253
PubMedID: 30582985

Title : Identification and Analysis of Putative Polyhydroxyalkanoate Synthase (PhaC) in Pseudomonas fluorescens - Lim_2018_J.Microbiol.Biotechnol_28_1133
Author(s) : Lim JH , Rhie HG , Kim JN
Ref : J Microbiol Biotechnol , 28 :1133 , 2018
Abstract :
PubMedSearch : Lim_2018_J.Microbiol.Biotechnol_28_1133
PubMedID: 29926705
Gene_locus related to this paper: psefl-q6xh00

Title : Production of poly(3-hydroxypropionate) and poly(3-hydroxybutyrate-co-3-hydroxypropionate) from glucose by engineering Escherichia coli - Meng_2015_Metab.Eng_29_189
Author(s) : Meng DC , Wang Y , Wu LP , Shen R , Chen JC , Wu Q , Chen GQ
Ref : Metab Eng , 29 :189 , 2015
Abstract :
PubMedSearch : Meng_2015_Metab.Eng_29_189
PubMedID: 25842374
Gene_locus related to this paper: alceu-phbc

Title : Compositional regulation of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by replacement of granule-associated protein in Ralstonia eutropha - Kawashima_2015_Microb.Cell.Fact_14_187
Author(s) : Kawashima Y , Orita I , Nakamura S , Fukui T
Ref : Microb Cell Fact , 14 :187 , 2015
Abstract :
PubMedSearch : Kawashima_2015_Microb.Cell.Fact_14_187
PubMedID: 26597300
Gene_locus related to this paper: alceu-phbc

Title : Class IV polyhydroxyalkanoate (PHA) synthases and PHA-producing Bacillus - Tsuge_2015_Appl.Microbiol.Biotechnol_99_6231
Author(s) : Tsuge T , Hyakutake M , Mizuno K
Ref : Applied Microbiology & Biotechnology , 99 :6231 , 2015
Abstract :
PubMedSearch : Tsuge_2015_Appl.Microbiol.Biotechnol_99_6231
PubMedID: 26135986

Title : A common active site of polyhydroxyalkanoate synthase from Bacillus cereus YB-4 is involved in polymerization and alcoholysis reactions - Hyakutake_2015_Appl.Microbiol.Biotechnol_99_4701
Author(s) : Hyakutake M , Tomizawa S , Mizuno K , Hisano T , Abe H , Tsuge T
Ref : Applied Microbiology & Biotechnology , 99 :4701 , 2015
Abstract :
PubMedSearch : Hyakutake_2015_Appl.Microbiol.Biotechnol_99_4701
PubMedID: 25503319
Gene_locus related to this paper: bacce-PHAC

Title : Metabolic engineering of Ralstonia eutropha for the biosynthesis of 2-hydroxyacid-containing polyhydroxyalkanoates - Park_2013_Metab.Eng_20_20
Author(s) : Park SJ , Jang YA , Lee H , Park AR , Yang JE , Shin J , Oh YH , Song BK , Jegal J , Lee SH , Lee SY
Ref : Metab Eng , 20 :20 , 2013
Abstract :
PubMedSearch : Park_2013_Metab.Eng_20_20
PubMedID: 23973656

Title : Revelation of the ability of Burkholderia sp. USM (JCM 15050) PHA synthase to polymerize 4-hydroxybutyrate monomer - Lau_2012_AMB.Express_2_41
Author(s) : Lau NS , Sudesh K
Ref : AMB Express , 2 :41 , 2012
Abstract :
PubMedSearch : Lau_2012_AMB.Express_2_41
PubMedID: 22877240
Gene_locus related to this paper: 9neis-e1apk1

Title : Hydroxybutyrate prevents protein aggregation in the halotolerant bacterium Pseudomonas sp. CT13 under abiotic stress - Soto_2012_Extremophiles_16_455
Author(s) : Soto G , Setten L , Lisi C , Maurelis C , Mozzicafreddo M , Cuccioloni M , Angeletti M , Ayub ND
Ref : Extremophiles , 16 :455 , 2012
Abstract :
PubMedSearch : Soto_2012_Extremophiles_16_455
PubMedID: 22527039

Title : Construction of pha-operon-defined knockout mutants of Pseudomonas putida KT2442 and their applications in poly(hydroxyalkanoate) production - Ouyang_2007_Macromol.Biosci_7_227
Author(s) : Ouyang SP , Liu Q , Fang L , Chen GQ
Ref : Macromol Biosci , 7 :227 , 2007
Abstract :
PubMedSearch : Ouyang_2007_Macromol.Biosci_7_227
PubMedID: 17295412

Title : Molecular cloning and functional analysis of two polyhydroxyalkanoate synthases from two strains of Aeromonas hydrophila spp - Lu_2005_FEMS.Microbiol.Lett_243_149
Author(s) : Lu X , Zhang W , Jian J , Wu Q , Chen GQ
Ref : FEMS Microbiology Letters , 243 :149 , 2005
Abstract :
PubMedSearch : Lu_2005_FEMS.Microbiol.Lett_243_149
PubMedID: 15668013
Gene_locus related to this paper: aerhy-PHAC

Title : Polyhydroxyalkanoate (PHA) accumulation in sulfate-reducing bacteria and identification of a class III PHA synthase (PhaEC) in Desulfococcus multivorans - Hai_2004_Appl.Environ.Microbiol_70_4440
Author(s) : Hai T , Lange D , Rabus R , Steinbuchel A
Ref : Applied Environmental Microbiology , 70 :4440 , 2004
Abstract :
PubMedSearch : Hai_2004_Appl.Environ.Microbiol_70_4440
PubMedID: 15294771
Gene_locus related to this paper: desml-phaCDm

Title : Engineering of Ralstonia eutropha for production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from fructose and solid-state properties of the copolymer - Fukui_2002_Biomacromolecules_3_618
Author(s) : Fukui T , Abe H , Doi Y
Ref : Biomacromolecules , 3 :618 , 2002
Abstract :
PubMedSearch : Fukui_2002_Biomacromolecules_3_618
PubMedID: 12005535

Title : Identification of the intracellular polyhydroxyalkanoate depolymerase gene of Paracoccus denitrificans and some properties of the gene product - Gao_2001_FEMS.Microbiol.Lett_196_159
Author(s) : Gao D , Maehara A , Yamane T , Ueda S
Ref : FEMS Microbiology Letters , 196 :159 , 2001
Abstract :
PubMedSearch : Gao_2001_FEMS.Microbiol.Lett_196_159
PubMedID: 11267773
Gene_locus related to this paper: parde-Q9WX79