PED-A1
Phospholipase A1 selective substrate TAG, with BODIPY fluor at sn-1 position and a dinitrophenyl quencher || PED-A1 is composed of a quencher group (dinitrophenyl) on the glycerophosphoethanolamine head group and BODIPY dye-labeled acyl chains at the sn-1 position. Cleavage of the molecule increases green fluorescence by uncoupling the quenched state. Specificity: PLA1
General
Type : Phospholipid, Fluorescent Probe, BODIPY-derivative, Boron compound, Indacen
Chemical_Nomenclature : N-{[6-(2,4-dinitrophenyl) amino] hexanoyl}-1-{4,4-difluoro-5,7-dimethyl-4-bora-3a,-4a-diaza-s-indacene-3-pentanoyl}-2-hexyl-sn-glycero-3-phosphoethanolamine
Canonical SMILES :
InChI :
InChIKey :
Other name(s) : A10070 || PED-A1 N-((6-(2,4-DNP)amino)hexanoyl)-1-(BODIPY-FL C5)-2-hexyl-sn-glycero-3-phosphoethanolamine
MW : 880.68
Formula : C39H56BF2N6O12P
CAS_number :
PubChem :
UniChem :
Target
Structures : No structure
Families : Lipoprotein_Lipase, Cutinase, Phospholipase, T6SS-TLE3
References (5)
| Title : Measurement of the phospholipase activity of endothelial lipase in mouse plasma - Basu_2013_J.Lipid.Res_54_282 |
| Author(s) : Basu D , Lei X , Josekutty J , Hussain MM , Jin W |
| Ref : J Lipid Res , 54 :282 , 2013 |
| Abstract : |
| PubMedSearch : Basu_2013_J.Lipid.Res_54_282 |
| PubMedID: 23103358 |
| Title : Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis - Dedieu_2013_PLoS.One_8_e66913 |
| Author(s) : Dedieu L , Serveau-Avesque C , Canaan S |
| Ref : PLoS ONE , 8 :e66913 , 2013 |
| Abstract : |
| PubMedSearch : Dedieu_2013_PLoS.One_8_e66913 |
| PubMedID: 23843969 |
| Gene_locus related to this paper: myctu-cutas1 , myctu-RV3452 |
| Title : A novel fluorogenic substrate for the measurement of endothelial lipase activity - Darrow_2011_J.Lipid.Res_52_374 |
| Author(s) : Darrow AL , Olson MW , Xin H , Burke SL , Smith C , Schalk-Hihi C , Williams R , Bayoumy SS , Deckman IC , Todd MJ , Damiano BP , Connelly MA |
| Ref : J Lipid Res , 52 :374 , 2011 |
| Abstract : |
| PubMedSearch : Darrow_2011_J.Lipid.Res_52_374 |
| PubMedID: 21062953 |
| Gene_locus related to this paper: human-LIPG |
| Title : In vitro analysis of LIPH mutations causing hypotrichosis simplex: evidence confirming the role of lipase H and lysophosphatidic acid in hair growth - Pasternack_2009_J.Invest.Dermatol_129_2772 |
| Author(s) : Pasternack SM , von Kugelgen I , Muller M , Oji V , Traupe H , Sprecher E , Nothen MM , Janecke AR , Betz RC |
| Ref : Journal of Investigative Dermatology , 129 :2772 , 2009 |
| Abstract : |
| PubMedSearch : Pasternack_2009_J.Invest.Dermatol_129_2772 |
| PubMedID: 19536142 |
| Gene_locus related to this paper: human-LIPH |
| Title : Genetic analysis of digestive physiology using fluorescent phospholipid reporters - Farber_2001_Science_292_1385 |
| Author(s) : Farber SA , Pack M , Ho SY , Johnson ID , Wagner DS , Dosch R , Mullins MC , Hendrickson HS , Hendrickson EK , Halpern ME |
| Ref : Science , 292 :1385 , 2001 |
| Abstract : |
| PubMedSearch : Farber_2001_Science_292_1385 |
| PubMedID: 11359013 |