Phospholipase
Relationship
Comment
Phospholipase A(1) (PLA(1)) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids and is conserved in a wide range of organisms. 
Hypotrichosis, or woolly hair with or without hypotrichosis hypotrichosis (deficiency of hair growth), can be caused by homozygous or compound heterozygous mutation in the LIPH (human-LIPH) gene on chromosome 3q27 (not hepatic lipase: human-LIPC). Other mammalian enzymes that exhibit PLA(1) activity in vitro are hepatic lipase HL endothelial lipase EL and pancreatic lipase-related protein 2 PLRP2 and belong to alpha/beta hydrolase superfamily.
Database
Interpro : IPR000734 Lipase , IPR002334 Dol\/Ves 1 allergen , IPR016272 Lipase, LIPH-type , IPR013818 Lipase
PIRSF : PIRSF000865 lipoprotein lipase, LIPH type
Pdoc : PDOC00110
Pfam : PF00151 Lipase
Prints : PR00821 , PR00825
EC Number : 3.1.1.32
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Gene_locus | Name | Species |
|---|---|---|
| bovin-q5e9h0 | Bos taurus (Bovine) phospholipase a1 member a | Bos taurus |
| danre-LIPH | Danio rerio (Zebrafish) (Brachydanio rerio) zgc:91985 | Danio rerio |
| danre-q6nyz4 | Danio rerio (Zebrafish) (Brachydanio rerio) hypothetical protein zgc:77160 | Danio rerio |
| human-LIPH | Homo sapiens (Human) membrane-bound phosphatidic acid-selective phospholipase a1-alpha, LPD lipase-related protein mPA-PLA1 alpha | Homo sapiens |
| human-LIPI | Homo sapiens (Human) membrane-associated phosphatidic acid-selective phospholipase a1 beta mPA-PLA1 beta (LPD lipase) Cancer\/testis antigen 17 CT17 | Homo sapiens |
| human-PLA1A | Homo sapiens (Human) Phospholipase A1 member A, phosphatidylserine-specific phospholipase A1 deltaC | Homo sapiens |
| mouse-LIPH | Mus musculus (Mouse) similar to lacrimal lipase | Mus musculus |
| mouse-psplip | Mus musculus Similar to phosphatidylserine-specific phospholipase A1alpha | Mus musculus |
| ponpy-q5ref0 | Pongo pygmaeus (Orangutan) hypothetical protein dkfzp469m0237 dkfzp469d0934 | Pongo pygmaeus |
| rabit-LIPH | Oryctolagus cuniculus (Rabbit) Lipase H (LIPH) (lacrimal lipase)\; Membrane-associated phosphatidic acid-selective phospholipase A1-alpha | Oryctolagus cuniculus |
| ratno-P97535 | Rattus norvegicus (Rat) ps-pla1 precursor | Rattus norvegicus |
| ratno-q6p6s8 | Rattus norvegicus (Rat) hypothetical protein (fragment) | Rattus norvegicus |
| tetng-q4rtq6 | Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) chromosome 2 scaf14997, Phospholipase A1 member A | Tetraodon nigroviridis |
| tetng-q4sfm7 | Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) hypothetical protein (fragment) | Tetraodon nigroviridis |
| tetng-q4szy0 | Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) chromosome undetermined scaf11458, whole genome shotgun sequence | Tetraodon nigroviridis |
| xenla-LIPHA | Xenopus laevis (African clawed frog) Lipase member H-A mgc68721 protein | Xenopus laevis |
| xenla-q641f6 | Xenopus laevis (African clawed frog) mgc81743 protein | Xenopus laevis |
| xentr-q5xge9 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) hypothetical loc496511 | Xenopus tropicalis |
| loxaf-g3syl2 | Loxodonta africana (African elephant). Phospholipase A1 member A | Loxodonta africana |
| muspf-m3yaj5 | Mustela putorius furo (European domestic ferret) (Mustela furo). Phospholipase A1 member A | Mustela putorius furo |
| colap-a0a2k5hwe4 | Colobus angolensis palliatus (Peters' Angolan colobus). Phospholipase A1 member A | Colobus angolensis palliatus |
| cebca-a0a2k5saj0 | Cebus capucinus imitator. Phospholipase A1 member A | Cebus capucinus imitator |
| macmu-g7mke4 | Macaca mulatta (Rhesus macaque). phospholipase A1 | Macaca mulatta |
| tupch-l8y4e3 | Tupaia chinensis (Chinese tree shrew). Phospholipase A1 member A | Tupaia chinensis |
| odoro-a0a2u3w611 | Odobenus rosmarus divergens (Pacific walrus). phospholipase A1 member A isoform X1 | Odobenus rosmarus divergens |
| balas-a0a384a3k8 | Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni). phospholipase A1 member A isoform X1 | Balaenoptera acutorostrata scammoni |
| proco-a0a2k6f1q8 | Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli). Phospholipase A1 member A | Propithecus coquereli |
| saibb-a0a2k6slq2 | Saimiri boliviensis boliviensis (Bolivian squirrel monkey). Phospholipase A1 member A | Saimiri boliviensis boliviensis |
| calja-a0a2r8myw2 | Callithrix jacchus (White-tufted-ear marmoset). Phospholipase A1 member A | Callithrix jacchus |
| enhlu-a0a2y9jsb1 | Enhydra lutris kenyoni (northern sea otter). phospholipase A1 member A isoform X1 | Enhydra lutris kenyoni |
| sheep-w5qet9 | Ovis aries (Sheep). Phospholipase A1 member A | Ovis aries |
| otoga-h0wr71 | Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). Phospholipase A1 member A | Otolemur garnettii |
| phycd-a0a2y9eqh5 | Physeter catodon (Sperm whale) (Physeter macrocephalus). phospholipase A1 member A | Physeter catodon |
| sarha-g3vcj1 | Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). Phospholipase A1 member A | Sarcophilus harrisii |
| neovi-u6csb5 | Neovison vison (American mink) (Mustela vison). Phospholipase A1 member A | Neovison vison |
| chlsb-a0a0d9r3z2 | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus). Phospholipase A1 member A | Chlorocebus sabaeus |
| horse-f6vts1 | Equus caballus (Horse). Phospholipase A1 member A | Equus caballus |
| lepwe-a0a2u3xg75 | Leptonychotes weddellii (Weddell seal). phospholipase A1 member A-like | Leptonychotes weddellii |
| ponab-a0a2j8w280 | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). PLA1A isoform 1 | Pongo abelii |
| felca-m3w589 | Felis catus (Cat) (Felis silvestris catus). Phospholipase A1 member A | Felis catus |
| neosc-a0a2y9hfa8 | Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi). phospholipase A1 member A | Neomonachus schauinslandi |
| lipve-a0a340wq60 | Lipotes vexillifer (Yangtze river dolphin). phospholipase A1 member A isoform X1 | Lipotes vexillifer |
| trima-a0a2y9dgm8 | Trichechus manatus latirostris (Florida manatee). phospholipase A1 member A | Trichechus manatus latirostris |
| panpa-a0a2r8zm37 | Pan paniscus (Pygmy chimpanzee) (Bonobo). Phospholipase A1 member A | Pan paniscus |
| tarsy-a0a1u7ssj2 | Tarsius syrichta (Philippine tarsier). phospholipase A1 member A-like | Tarsius syrichta |
| erieu-a0a1s3wna7 | Erinaceus europaeus (Western European hedgehog). phospholipase A1 member A isoform X1 | Erinaceus europaeus |
| mondo-f7b6s6 | Monodelphis domestica (Gray short-tailed opossum). Phospholipase A1 member A | Monodelphis domestica |
| papan-a0a096nsf6 | Papio anubis (Olive baboon). Phospholipase A1 member A | Papio anubis |
| aotna-a0a2k5diw6 | Aotus nancymaae (Ma's night monkey). Phospholipase A1 member A | Aotus nancymaae |
| rhiro-a0a2k6q4a6 | Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana). Phospholipase A1 member A | Rhinopithecus roxellana |
| cerat-a0a2k5mu56 | Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys). Phospholipase A1 member A | Cercocebus atys |
| pantr-h2qn58 | Pan troglodytes (Chimpanzee). Phospholipase A1 member A | Pan troglodytes |
| pig-a0a287bc40 | Sus scrofa (Pig). Phospholipase A1 member A | Sus scrofa |
| 9ceta-a0a341czt0 | Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise). phospholipase A1 member A isoform X1 | Neophocaena asiaeorientalis asiaeorientalis |
| pteal-l5l3r3 | Pteropus alecto (Black flying fox). Phospholipase A1 member A | Pteropus alecto |
| manle-a0a2k5zjb7 | Mandrillus leucophaeus (Drill) (Papio leucophaeus). Phospholipase A1 member A | Mandrillus leucophaeus |
| macfa-g7nxn9 | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Uncharacterized protein | Macaca fascicularis |
| 9ceta-a0a341d2l4 | Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise). phospholipase A1 member A isoform X2 | Neophocaena asiaeorientalis asiaeorientalis |
| gorgo-g3qkj4 | Gorilla gorilla gorilla (Western lowland gorilla). Phospholipase A1 member A | Gorilla gorilla gorilla |
| nomle-a0a2i3hj53 | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Phospholipase A1 member A | Nomascus leucogenys |
| ailme-g1lkt7 | Ailuropoda melanoleuca (Giant panda). Phospholipase A1 member A | Ailuropoda melanoleuca |
| canlf-e2qxh0 | Canis lupus familiaris (Dog) (Canis familiaris). Phospholipase A1 member A | Canis lupus familiaris |
| 9ceta-l8hyl8 | Bos mutus (wild yak). Phospholipase A1 member A | Bos mutus |
| ursma-a0a384dha8 | Ursus maritimus (Polar bear) (Thalarctos maritimus). phospholipase A1 member A isoform X2 | Ursus maritimus |
| macne-a0a2k6c950 | Macaca nemestrina (Pig-tailed macaque). Phospholipase A1 member A | Macaca nemestrina |
| myolu-g1pan2 | Myotis lucifugus (Little brown bat). Phospholipase A1 member A | Myotis lucifugus |
| rhibe-a0a2k6l7h4 | Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti). Phospholipase A1 member A | Rhinopithecus bieti |
| rabit-g1sxd0 | Oryctolagus cuniculus (Rabbit). Phospholipase A1 member A | Oryctolagus cuniculus |
| myods-l5mdx5 | Myotis davidii (David's myotis). Phospholipase A1 member A | Myotis davidii |
| salsa-b5x239 | Salmo salar (Atlantic salmon). phospholipase A1 member A precursor | Salmo salar |
| salsa-a0a1s3ny08 | Salmo salar (Atlantic salmon). phospholipase A1 member A-like isoform X6 | Salmo salar |
| 9tele-a0a1a8grp8 | Nothobranchius korthausae. Phospholipase A1 member A | Nothobranchius korthausae |
| mernu-a0a091r5l0 | Merops nubicus (Northern carmine bee-eater). Lipase member H | Merops nubicus |
| taegu-h0zt33 | Taeniopygia guttata (Zebra finch) (Poephila guttata). Uncharacterized protein | Taeniopygia guttata |
| 9tele-a0a1a7z071 | Iconisemion striatum. Phospholipase A1 member A | Iconisemion striatum |
| crigr-g3i1j5 | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus). Phospholipase A1 member A | Cricetulus griseus |
| mesau-a0a1u7qnx8 | Mesocricetus auratus (Golden hamster). phospholipase A1 member A | Mesocricetus auratus |
| dipor-a0a1s3ffm5 | Dipodomys ordii (Ord's kangaroo rat). phospholipase A1 member A | Dipodomys ordii |
| cavpo-h0v8j4 | Cavia porcellus (Guinea pig). Phospholipase A1 member A | Cavia porcellus |
| cascn-a0a250y135 | Castor canadensis (Beaver). Phospholipase A1 member A | Castor canadensis |
| icttr-i3m3b3 | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Phospholipase A1 member A | Ictidomys tridecemlineatus |
| neole-a0a1a6gyh1 | Neotoma lepida (Desert woodrat). Uncharacterized protein | Neotoma lepida |
| hetga-g5aua1 | Heterocephalus glaber (Naked mole rat). Phospholipase A1 member A isoform 1 | Heterocephalus glaber |
| fukda-a0a091di51 | Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis). Phospholipase A1 member A | Fukomys damarensis |
| pelsi-k7fhg2 | Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis). Phospholipase A1 member A | Pelodiscus sinensis |
| poefo-a0a087yji4 | Poecilia formosa (Amazon molly) (Limia formosa)\; Poecilia latipinna (sailfin molly)\; Poecilia mexicana. Phospholipase A1 member A | Poecilia formosa |
| balre-a0a087v840 | Balearica regulorum gibbericeps (East African grey crowned-crane). Phospholipase A1 member A | Balearica regulorum gibbericeps |
| 9tele-a0a1w4z4k7 | Scleropages formosus (Asian bonytongue). LOW QUALITY PROTEIN: phospholipase A1 member A-like | Scleropages formosus |
| oncmy-a0a060w5s8 | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein | Oncorhynchus mykiss |
| oryme-a0a3b3dpk3 | Oryzias melastigma (Marine medaka). Uncharacterized protein | Oryzias melastigma |
| anoca-h9g7n4 | Anolis carolinensis (Green anole) (American chameleon). Phospholipase A1 member A | Anolis carolinensis |
| gavst-a0a093fhe9 | Gavia stellata (Red-throated diver) (Red-throated loon). Phospholipase A1 member A | Gavia stellata |
| 9tele-a0a2i4ctk9 | Austrofundulus limnaeus. phospholipase A1 member A | Austrofundulus limnaeus |
| 9tele-a0a3b3qvg4 | Paramormyrops kingsleyae. Uncharacterized protein | Paramormyrops kingsleyae |
| lepoc-w5mt16 | Lepisosteus oculatus (Spotted gar). Uncharacterized protein | Lepisosteus oculatus |
| ictpu-a0a2d0r4d9 | Ictalurus punctatus (Channel catfish) (Silurus punctatus). phospholipase A1 member A isoform X4 | Ictalurus punctatus |
| xipma-a0a3b5r0c8 | Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus). Phospholipase A1 member A | Xiphophorus maculatus |
| phaca-a0a093qxf4 | Phalacrocorax carbo (Great cormorant) (Pelecanus carbo). Phospholipase A1 member A | Phalacrocorax carbo |
| larcr-a0a0f8aed8 | Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea). Phospholipase A1 member A | Larimichthys crocea |
| gasac-g3n954 | Gasterosteus aculeatus (Three-spined stickleback). Phospholipase A1 member A | Gasterosteus aculeatus |
| 9pass-a0a093saf7 | Manacus vitellinus (golden-collared manakin). Phospholipase A1 member A | Manacus vitellinus |
| phorb-a0a091ufk8 | Phoenicopterus ruber ruber. Phospholipase A1 member A | Phoenicopterus ruber ruber |
| 9aves-a0a091fup2 | Cuculus canorus (common cuckoo). Phospholipase A1 member A | Cuculus canorus |
| nipni-a0a091ur65 | Nipponia nippon (Crested ibis) (Ibis nippon). Phospholipase A1 member A | Nipponia nippon |
| calan-a0a091i8n4 | Calypte anna (Anna's hummingbird) (Archilochus anna). Phospholipase A1 member A | Calypte anna |
| 9pase-a0a218ve49 | Lonchura striata domestica (Bengalese finch). Phospholipase A1 member A | Lonchura striata domestica |
| opiho-a0a091wgz8 | Opisthocomus hoazin (Hoatzin) (Phasianus hoazin). Phospholipase A1 member A | Opisthocomus hoazin |
| colvi-a0a226pth1 | Colinus virginianus (Northern bobwhite) (Tetrao virginianus). Uncharacterized protein | Colinus virginianus |
| drypu-a0a093gb67 | Dryobates pubescens (Downy woodpecker) (Picoides pubescens). Lipase member H-A | Dryobates pubescens |
| drypu-a0a093gsl9 | Dryobates pubescens (Downy woodpecker) (Picoides pubescens). Phospholipase A1 member A | Dryobates pubescens |
| oreni-i3kf65 | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). Phospholipase A1 member A | Oreochromis niloticus |
| chick-f1nm35 | Gallus gallus (Chicken). Phospholipase A1 member A | Gallus gallus |
| serdu-a0a3b4um04 | Seriola dumerili (Mediterranean greater amberjack) (Caranx dumerili). Uncharacterized protein | Seriola dumerili |
| patfa-a0a1v4j3h9 | Patagioenas fasciata monilis. Phospholipase A1 member A | Patagioenas fasciata monilis |
| calmi-v9kdh1 | Callorhinchus milii (Ghost shark). Phospholipase A1 member A | Callorhinchus milii |
| antcr-a0a094kqc1 | Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis). Phospholipase A1 member A | Antrostomus carolinensis |
| eurhl-a0a093lqc7 | Eurypyga helias (Sunbittern). Phospholipase A1 member A | Eurypyga helias |
| oryla-h2lxe3 | Oryzias latipes (Japanese rice fish) (Japanese killifish). Phospholipase A1 member A | Oryzias latipes |
| astmx-w5kdz8 | Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Phospholipase A1 member A | Astyanax mexicanus |
| ophha-v8nra3 | Ophiophagus hannah (King cobra) (Naja hannah). Lipase member H-A | Ophiophagus hannah |
| pelcr-a0a091tn00 | Pelecanus crispus (Dalmatian pelican). Phospholipase A1 member A | Pelecanus crispus |
| 9grui-a0a091r6z1 | Mesitornis unicolor (brown roatelo). Phospholipase A1 member A | Mesitornis unicolor |
| latch-m3xgg9 | Latimeria chalumnae (West Indian ocean coelacanth). Uncharacterized protein | Latimeria chalumnae |
| strca-a0a093h5a0 | Struthio camelus australis. Phospholipase A1 member A | Struthio camelus australis |
| egrga-a0a091j5e1 | Egretta garzetta (Little egret). Phospholipase A1 member A | Egretta garzetta |
| amaae-a0a0q3sg10 | Amazona aestiva (Blue-fronted Amazon parrot). Phospholipase A1 member A | Amazona aestiva |
| chavo-a0a0a0a6m1 | Charadrius vociferus (Killdeer) (Aegialitis vocifera). Phospholipase A1 member A | Charadrius vociferus |
| corbr-a0a091emx6 | Corvus brachyrhynchos (American crow). Phospholipase A1 member A | Corvus brachyrhynchos |
| pygna-a0a3b4c175 | Pygocentrus nattereri (Red-bellied piranha). Phospholipase A1 member A | Pygocentrus nattereri |
| colli-a0a2i0ms89 | Columba livia (Rock dove). Phospholipase A1 member A, transcript variant X1 | Columba livia |
| 9grui-a0a091kbl6 | Chlamydotis macqueenii (Macqueen's bustard). Phospholipase A1 member A | Chlamydotis macqueenii |
| tytal-a0a093fms0 | Tyto alba (Barn owl). Phospholipase A1 member A | Tyto alba |
| pygad-a0a093n9l5 | Pygoscelis adeliae (Adelie penguin). Phospholipase A1 member A | Pygoscelis adeliae |
| allsi-a0a1u8dkd7 | Alligator sinensis (Chinese alligator). phospholipase A1 member A isoform X2 | Alligator sinensis |
| notfu-a0a1a8aba8 | Nothobranchius furzeri (Turquoise killifish)\; Nothobranchius kuhntae (Beira killifish)\; Nothobranchius kadleci\; Nothobranchius pienaari\; Nothobranchius rachovii (bluefin notho). Phospholipase A1 member A | Nothobranchius furzeri |
| aptfo-a0a087qhn8 | Aptenodytes forsteri (Emperor penguin). Phospholipase A1 member A | Aptenodytes forsteri |
| 9aves-a0a093cg37 | Pterocles gutturalis (yellow-throated sandgrouse). Phospholipase A1 member A | Pterocles gutturalis |
| 9gobi-a0a3b4bh68 | Periophthalmus magnuspinnatus. Uncharacterized protein | Periophthalmus magnuspinnatus |
| fical-u3js71 | Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis). Phospholipase A1 member A | Ficedula albicollis |
| 9pass-a0a091mfq2 | Acanthisitta chloris (rifleman). Phospholipase A1 member A | Acanthisitta chloris |
| phalp-a0a091tuq9 | Phaethon lepturus (White-tailed tropicbird). Phospholipase A1 member A | Phaethon lepturus |
| scomx-a0a2u9caf7 | Scophthalmus maximus (Turbot) (Psetta maxima). Putative phospholipase A1 member A | Scophthalmus maximus |
| 9tele-a0a3b5azk7 | Stegastes partitus (bicolor damselfish). Uncharacterized protein | Stegastes partitus |
| xenla-a0a1l8hc38 | Xenopus laevis (African clawed frog). Uncharacterized protein | Xenopus laevis |
| tauer-a0a093crq4 | Tauraco erythrolophus (Red-crested turaco). Phospholipase A1 member A | Tauraco erythrolophus |
| tingu-a0a099z2v8 | Tinamus guttatus (White-throated tinamou). Phospholipase A1 member A | Tinamus guttatus |
| 9tele-a0a3b5adq0 | Stegastes partitus (bicolor damselfish). Uncharacterized protein | Stegastes partitus |
| bucrh-a0a091heg3 | Buceros rhinoceros silvestris. Phospholipase A1 member A | Buceros rhinoceros silvestris |
| allmi-a0a151mdf3 | Alligator mississippiensis (American alligator). Phospholipase A1 member A | Alligator mississippiensis |
| fulga-a0a093lax2 | Fulmarus glacialis (Northern fulmar). Phospholipase A1 member A | Fulmarus glacialis |
| funhe-a0a146v756 | Fundulus heteroclitus (Killifish) (Mummichog). Phospholipase A1 member A | Fundulus heteroclitus |
| serll-a0a3b4xjq8 | Seriola lalandi dorsalis. Uncharacterized protein | Seriola lalandi dorsalis |
| colst-a0a091k2a2 | Colius striatus (Speckled mousebird). Phospholipase A1 member A | Colius striatus |
| melga-g1nna9 | Meleagris gallopavo (Wild turkey). Phospholipase A1 member A | Meleagris gallopavo |
| takru-h2uuz8 | Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). Phospholipase A1 member A | Takifugu rubripes |
| pantr-h2r0m0 | Pan troglodytes (Chimpanzee). Lipase H | Pan troglodytes |
| panpa-a0a2r9bpf0 | Pan paniscus (Pygmy chimpanzee) (Bonobo). Lipase H | Pan paniscus |
| gorgo-g3s122 | Gorilla gorilla gorilla (Western lowland gorilla). Lipase H | Gorilla gorilla gorilla |
| nomle-g1r3w4 | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Lipase H | Nomascus leucogenys |
| ponab-h2pc84 | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). Lipase H | Pongo abelii |
| rhibe-a0a2k6k333 | Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)\; Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)\; Colobus angolensis palliatus (Peters' Angolan colobus). Lipase H | Rhinopithecus bieti |
| macne-a0a2k6bl45 | Macaca nemestrina (Pig-tailed macaque). Lipase H | Macaca nemestrina |
| macmu-f7hp78 | Macaca mulatta (Rhesus macaque). Lipase domain-containing protein | Macaca mulatta |
| papan-a0a2i3ndh3 | Papio anubis (Olive baboon). Lipase H | Papio anubis |
| manle-a0a2k5xn36 | Mandrillus leucophaeus (Drill) (Papio leucophaeus). Lipase H | Mandrillus leucophaeus |
| chlsb-a0a0d9rnf2 | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus). Lipase H | Chlorocebus sabaeus |
| cerat-a0a2k5na00 | Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys). Lipase H | Cercocebus atys |
| saibb-a0a2k6t729 | Saimiri boliviensis boliviensis (Bolivian squirrel monkey). Lipase H | Saimiri boliviensis boliviensis |
| cebca-a0a2k5rjf4 | Cebus capucinus imitator. Lipase H | Cebus capucinus imitator |
| aotna-a0a2k5e8w4 | Aotus nancymaae (Ma's night monkey). Lipase H | Aotus nancymaae |
| calja-f7ff96 | Callithrix jacchus (White-tufted-ear marmoset). Lipase member H | Callithrix jacchus |
| macfa-a0a2k5u0a0 | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Lipase H | Macaca fascicularis |
| delle-a0a2y9mw48 | Delphinapterus leucas (Beluga whale)\; Lipotes vexillifer (Yangtze river dolphin)\; Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)\; Balaenoptera acutorostrata scammoni (North Pacific minke whale)\; Odobenus rosmarus divergens (Pacific walrus)\; Sousa chinensis (Indo-pacific humpbacked dolphin) (Steno chinensis)\; Tursiops truncatus (Atlantic bottle-nosed dolphin))\; Physeter macrocephalus (Sperm whale)\; Trichechus manatus latirostris (Florida manatee). lipase member H | Delphinapterus leucas |
| ursma-a0a384d909 | Ursus maritimus (Polar bear) (Thalarctos maritimus)\; Ursus arctos horribilis\; Ursus americanus (American black bear) (Euarctos americanus). lipase member H | Ursus maritimus |
| pig-f1sfk2 | Sus scrofa (Pig). Lipase H | Sus scrofa |
| caphi-a0a452ekh7 | Capra hircus (Goat). Lipase H | Capra hircus |
| felca-a0a337s3d4 | Felis catus (Cat) (Felis silvestris catus). Lipase H | Felis catus |
| bovin-f1mxa8 | Bos taurus (Bovine). Lipase H | Bos taurus |
| canlf-f1pg57 | Canis lupus familiaris (Dog) (Canis familiaris). Lipase H | Canis lupus familiaris |
| sheep-w5qh96 | Ovis aries (Sheep). Lipase H | Ovis aries |
| gulgu-a0a3p4rab0 | Gulo gulo (Wolverine) (Gluton). Lipase domain-containing protein | Gulo gulo |
| horse-f7am73 | Equus caballus (Horse). Lipase H | Equus caballus |
| muspf-m3xvd9 | Mustela putorius furo (European domestic ferret) (Mustela furo). Lipase H | Mustela putorius furo |
| neosc-a0a2y9h918 | Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi). lipase member H | Neomonachus schauinslandi |
| proco-a0a2k6h089 | Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli). Lipase H | Propithecus coquereli |
| enhlu-a0a2y9k136 | Enhydra lutris kenyoni. lipase member H | Enhydra lutris kenyoni |
| ailme-g1meh3 | Ailuropoda melanoleuca (Giant panda). Lipase H | Ailuropoda melanoleuca |
| tarsy-a0a1u7u721 | Tarsius syrichta (Philippine tarsier). lipase member H isoform X1 | Tarsius syrichta |
| dipor-a0a1s3gqh9 | Dipodomys ordii (Ord's kangaroo rat). lipase member H | Dipodomys ordii |
| myolu-g1p353 | Myotis lucifugus (Little brown bat)\; Myotis brandtii (Brandt's bat). Lipase H | Myotis lucifugus |
| vulvu-a0a3q7t0n8 | Vulpes vulpes (Red fox). lipase member H | Vulpes vulpes |
| icttr-i3mgy6 | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Lipase H | Ictidomys tridecemlineatus |
| pteal-l5jrl1 | Pteropus alecto (Black flying fox). Lipase member H | Pteropus alecto |
| erieu-a0a1s2zif6 | Erinaceus europaeus (Western European hedgehog). lipase member H | Erinaceus europaeus |
| mesau-a0a1u8bs49 | Mesocricetus auratus (Golden hamster). lipase member H | Mesocricetus auratus |
| loxaf-g3tib0 | Loxodonta africana (African elephant). Lipase H | Loxodonta africana |
| fical-u3kg45 | Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis) Lipase H \; || Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis). Lipase H | Ficedula albicollis |
| fukda-a0a091dsh1 | Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis). Lipase member H | Fukomys damarensis |
| hetga-g5bt99 | Heterocephalus glaber (Naked mole rat). Lipase member H | Heterocephalus glaber |
| cavpo-h0vpm0 | Cavia porcellus (Guinea pig). Lipase H | Cavia porcellus |
| sarha-g3whf6 | Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). Lipase H | Sarcophilus harrisii |
| vomur-a0a4x2jv00 | Vombatus ursinus (Common wombat). Lipase domain-containing protein | Vombatus ursinus |
| 9saur-a0a452ha67 | Gopherus agassizii (Agassiz's desert tortoise). Lipase H | Gopherus agassizii |
| 9saur-a0a452hgt6 | Gopherus agassizii (Agassiz's desert tortoise). Lipase domain-containing protein | Gopherus agassizii |
| 9saur-a0a4d9ek33 | Platysternon megacephalum (big-headed turtle). ABI protein family member 3 | Platysternon megacephalum |
| pelsi-k7gjb0 | Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis). Lipase H | Pelodiscus sinensis |
| pelsi-k7ghp3 | Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis). Lipase domain-containing protein | Pelodiscus sinensis |
| mondo-f6z6x9 | Monodelphis domestica (Gray short-tailed opossum). Lipase H | Monodelphis domestica |
| allsi-a0a1u8cyp8 | Alligator sinensis (Chinese alligator)\; Alligator mississippiensis (American alligator). lipase member H isoform X1 | Alligator sinensis |
| anapl-r0lin6 | Anas platyrhynchos (Mallard) (Anas boschas)\; Anas platyrhynchos platyrhynchos (Northern mallard). Lipase member H | Anas platyrhynchos |
| taegu-h0z994 | Taeniopygia guttata (Zebra finch) (Poephila guttata). Lipase H | Taeniopygia guttata |
| allsi-a0a1u7s8q9 | Alligator sinensis (Chinese alligator)\; Alligator mississippiensis (American alligator). lipase member H isoform X2 | Alligator sinensis |
| chick-f1p2g7 | Gallus gallus (Chicken). Lipase H | Gallus gallus |
| 9saur-a0a4d9e2x5 | Platysternon megacephalum (big-headed turtle). C-X-C motif chemokine 11 | Platysternon megacephalum |
| cereh-a0a212ci67 | Cervus elaphus hippelaphus (European red deer). Lipase domain-containing protein | Cervus elaphus hippelaphus |
| tingu-a0a099zl61 | Tinamus guttatus (White-throated tinamou). Lipase member H | Tinamus guttatus |
| vomur-a0a4x2jv14 | Vombatus ursinus (Common wombat). Lipase domain-containing protein | Vombatus ursinus |
| anapl-r0jhf3 | Anas platyrhynchos (Mallard) (Anas boschas)\; Anas platyrhynchos platyrhynchos (Northern mallard). Lipase member H | Anas platyrhynchos |
| melga-g1mtx9 | Meleagris gallopavo (Wild turkey). Lipase H | Meleagris gallopavo |
| fical-u3kcb5 | Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis). Lipase domain-containing protein | Ficedula albicollis |
| melga-g1nns1 | Meleagris gallopavo (Wild turkey). Lipase domain-containing protein | Meleagris gallopavo |
| crigr-g3hkm8 | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus). Lipase member H | Cricetulus griseus |
| anoca-h9g3p8 | Anolis carolinensis (Green anole) (American chameleon). Lipase domain-containing protein | Anolis carolinensis |
| taegu-h0ztj6 | Taeniopygia guttata (Zebra finch) (Poephila guttata). Lipase domain-containing protein | Taeniopygia guttata |
| chick-f1nd96 | Gallus gallus (Chicken). Lipase domain-containing protein | Gallus gallus |
| latch-h3amx7 | Latimeria chalumnae (Coelacanth). Lipase H | Latimeria chalumnae |
| salsa-a0a1s3rhi8 | Salmo salar (Atlantic salmon). lipase member H-like | Salmo salar |
| 9tele-a0a4w5r8h5 | Hucho hucho (huchen). Lipase, member Ia | Hucho hucho |
| 9tele-a0a4w5nna2 | Hucho hucho (huchen). Lipase domain-containing protein | Hucho hucho |
| esolu-a0a3p8z0k4 | Esox lucius (Northern pike). Lipase, member Ia | Esox lucius |
| salsa-c0hav5 | Salmo salar (Atlantic salmon). Lipase member H precursor | Salmo salar |
| astmx-a0a3b1k1i9 | Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Lipase, member Ia | Astyanax mexicanus |
| astmx-w5l3f7 | Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Lipase, member Ib | Astyanax mexicanus |
| danre-f1qtr2 | Danio rerio (Zebrafish) (Brachydanio rerio). Lipase, member Ib | Danio rerio |
| calmi-a0a4w3hel5 | Callorhinchus milii (Ghost shark). Lipase domain-containing protein | Callorhinchus milii |
| gasac-g3qbs4 | Gasterosteus aculeatus (Three-spined stickleback). Lipase, member Ia | Gasterosteus aculeatus |
| panpa-a0a2r9cj39 | Pan paniscus (Pygmy chimpanzee) (Bonobo). Lipase I | Pan paniscus |
| pantr-h2qku7 | Pan troglodytes (Chimpanzee). Lipase I | Pan troglodytes |
| nomle-g1qma2 | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Lipase I | Nomascus leucogenys |
| ponab-h2p2r5 | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). Lipase I | Pongo abelii |
| saibb-a0a2k6sbc6 | Saimiri boliviensis boliviensis (Bolivian squirrel monkey). Lipase I | Saimiri boliviensis boliviensis |
| aotna-a0a2k5esh0 | Aotus nancymaae (Ma's night monkey). Lipase I | Aotus nancymaae |
| cebca-a0a2k5r3e2 | Cebus capucinus imitator. Lipase I | Cebus capucinus imitator |
| calja-f7hr65 | Callithrix jacchus (White-tufted-ear marmoset). Lipase I | Callithrix jacchus |
| macfa-a0a2k5tze4 | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Lipase I | Macaca fascicularis |
| macmu-a0a1d5qvu5 | Macaca mulatta (Rhesus macaque). Lipase I | Macaca mulatta |
| rhibe-a0a2k6mff5 | Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)\; Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana). Lipase I | Rhinopithecus bieti |
| cerat-a0a2k5mny8 | Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys). Lipase I | Cercocebus atys |
| gorgo-a0a2i2y3x8 | Gorilla gorilla gorilla (Western lowland gorilla). Lipase I | Gorilla gorilla gorilla |
| macne-a0a2k6cpm2 | Macaca nemestrina (Pig-tailed macaque). Lipase I | Macaca nemestrina |
| chlsb-a0a0d9r8q4 | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus). Lipase I | Chlorocebus sabaeus |
| rabit-a0a5f9cru6 | Oryctolagus cuniculus (Rabbit). Lipase I | Oryctolagus cuniculus |
| delle-a0a2y9nbj5 | Delphinapterus leucas (Beluga whale)\; Trichechus manatus latirostris (Florida manatee)\; Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)\; Odobenus rosmarus divergens (Pacific walrus)\; Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi)\; Lipotes vexillifer (Yangtze river dolphin)\; Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)\; Physeter macrocephalus (Sperm whale) (Physeter catodon) Balaenoptera acutorostrata scammoni (North Pacific minke whale). lipase member I isoform X1 | Delphinapterus leucas |
| otoga-h0wss5 | Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). Lipase I | Otolemur garnettii |
| colap-a0a2k5izs3 | Colobus angolensis palliatus (Peters' Angolan colobus). Lipase I | Colobus angolensis palliatus |
| horse-f7dme2 | Equus caballus (Horse). Lipase I | Equus caballus |
| pig-a0a286zjp4 | Sus scrofa (Pig). Lipase I | Sus scrofa |
| tupch-l9khv5 | Tupaia chinensis (Chinese tree shrew). Lipase member I | Tupaia chinensis |
| ursma-a0a384cyu0 | Ursus maritimus (Polar bear) (Thalarctos maritimus)\; Ursus arctos horribilis. lipase member I isoform X1 | Ursus maritimus |
| sheep-w5q4p1 | Ovis aries (Sheep). Lipase I | Ovis aries |
| caphi-a0a452fss8 | Capra hircus (Goat). Lipase I | Capra hircus |
| loxaf-g3tfe2 | Loxodonta africana (African elephant). Lipase I | Loxodonta africana |
| felca-m3x0w7 | Felis catus (Cat) (Felis silvestris catus). Lipase I | Felis catus |
| canlf-f1q111 | Canis lupus familiaris (Dog) (Canis familiaris). Lipase I | Canis lupus familiaris |
| ailme-g1m719 | Ailuropoda melanoleuca (Giant panda). Lipase I | Ailuropoda melanoleuca |
| erieu-a0a1s3aeu7 | Erinaceus europaeus (Western European hedgehog). lipase member I | Erinaceus europaeus |
| hetga-g5b4q4 | Heterocephalus glaber (Naked mole rat). Lipase member I | Heterocephalus glaber |
| enhlu-a0a2y9jc22 | Enhydra lutris kenyoni. lipase member I | Enhydra lutris kenyoni |
| icttr-i3mlm0 | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Lipase I | Ictidomys tridecemlineatus |
| cavpo-a0a286xtc0 | Cavia porcellus (Guinea pig). Lipase I | Cavia porcellus |
| fukda-a0a091dmz8 | Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis). Lipase member I | Fukomys damarensis |
| mouse-f6yqt7 | Mus musculus (Mouse). Lipase, member I | Mus musculus |
| muspf-m3ygz2 | Mustela putorius furo (European domestic ferret) (Mustela furo). Lipase I | Mustela putorius furo |
| rat-d3zmg4 | Rattus norvegicus (Rat). Lipase, member H (Predicted) | Rattus norvegicus |
| mesau-a0a1u7q4b7 | Mesocricetus auratus (Golden hamster). lipase member I | Mesocricetus auratus |
| vomur-a0a4x2k0l1 | Vombatus ursinus (Common wombat). Lipase domain-containing protein | Vombatus ursinus |
| ornan-f7cgn4 | Ornithorhynchus anatinus (Duckbill platypus). Lipase domain-containing protein | Ornithorhynchus anatinus |
| Gene_locus_frgt | Name | Species |
|---|---|---|
| polga-P83542 | Polistes gallicus (Paper wasp) phospholipase a1 (EC 3.1.1.32) (allergen pol g 1) (fragment) | Polistes gallicus |
| solin-Q9TXF4 | Solenopsis invicta (Red imported fire ant) solI1 antigen (fragments) | Solenopsis invicta |
| turtr-a0a2u4a9r1 | Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus). phospholipase A1 member A | Tursiops truncatus |
| cereh-a0a212cjc9 | Cervus elaphus hippelaphus (European red deer). PLA1A | Cervus elaphus hippelaphus |
| camfr-s9weg5 | Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus). Uncharacterized protein | Camelus ferus |
| myobr-s7naq0 | Myotis brandtii (Brandt's bat). [Protein ADP-ribosylarginine] hydrolase | Myotis brandtii |
| delle-a0a2y9mni8 | Delphinapterus leucas (Beluga whale). phospholipase A1 member A-like | Delphinapterus leucas |
| anapl-r0lbk0 | Anas platyrhynchos (Mallard) (Anas boschas). Phospholipase A1 member A | Anas platyrhynchos |
| 9tele-a0a3b5miz0 | Xiphophorus couchianus (Monterrey platyfish). Uncharacterized protein | Xiphophorus couchianus |
| calsu-a0a226nm87 | Callipepla squamata (Scaled quail). Uncharacterized protein | Callipepla squamata |
| lepdc-a0a091pva6 | Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor). Phospholipase A1 member A | Leptosomus discolor |
| litct-a0a2g9rep1 | Lithobates catesbeiana (American bullfrog) (Rana catesbeiana). Uncharacterized protein | Lithobates catesbeiana |
| 9cich-a0a3b4fcw3 | Pundamilia nyererei. Uncharacterized protein | Pundamilia nyererei |
| otoga-h0xkq0 | Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). Lipase H | Otolemur garnettii |
| manle-a0a2k5ys79 | Mandrillus leucophaeus (Drill) (Papio leucophaeus). Lipase I | Mandrillus leucophaeus |
| dipor-a0a1s3gqv1 | Dipodomys ordii (Ord's kangaroo rat). lipase member I | Dipodomys ordii |
| papan-a0a096nh65 | Papio anubis (Olive baboon). Lipase I | Papio anubis |
| vulvu-a0a3q7s989 | Vulpes vulpes (Red fox). lipase member I | Vulpes vulpes |
| gulgu-a0a3p4mxk8 | Gulo gulo (Wolverine) (Gluton). Lipase domain-containing protein | Gulo gulo |
| Substrate | Chemical Nomenclature | Proteins |
|---|---|---|
| Lysophosphatidylserine | (2~{S})-2-amino-3-[hydroxy-[(2~{R})-2-hydroxy-3-octadecanoyloxypropoxy]phosphoryl]oxypropanoic acid | human-ABHD12 human-PLA1A yeast-FSH1 |
| PED-A1 | N-{[6-(2,4-dinitrophenyl) amino] hexanoyl}-1-{4,4-difluoro-5,7-dimethyl-4-bora-3a,-4a-diaza-s-indacene-3-pentanoyl}-2-hexyl-sn-glycero-3-phosphoethanolamine | human-LIPH ecoli-T6SS.TLE3 |
| Dioleoyl-phosphatidylserine | (2S)-2-amino-3-[[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-hydroxyphosphoryl]oxypropanoic acid | |
| Dioleoyllecithin | 2-[[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium | human-LIPH |
| POPC | [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | 9entr-PLAA |
References (3)
| Title : The Lysophosphatidylserines-An Emerging Class of Signalling Lysophospholipids - Shanbhag_2020_J.Membr.Biol_253_381 |
| Author(s) : Shanbhag K , Mhetre A , Khandelwal N , Kamat SS |
| Ref : J Membr Biol , 253 :381 , 2020 |
| Abstract : |
| PubMedSearch : Shanbhag_2020_J.Membr.Biol_253_381 |
| PubMedID: 32767057 |
| Title : Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family - Aoki_2007_Biochimie_89_197 |
| Author(s) : Aoki J , Inoue A , Makide K , Saiki N , Arai H |
| Ref : Biochimie , 89 :197 , 2007 |
| Abstract : |
| PubMedSearch : Aoki_2007_Biochimie_89_197 |
| PubMedID: 17101204 |
| Title : An alternative splicing form of phosphatidylserine-specific phospholipase A1 that exhibits lysophosphatidylserine-specific lysophospholipase activity in humans - Nagai_1999_J.Biol.Chem_274_11053 |
| Author(s) : Nagai Y , Aoki J , Sato T , Amano K , Matsuda Y , Arai H and |
| Ref : Journal of Biological Chemistry , 274 :11053 , 1999 |
| Abstract : |
| PubMedSearch : Nagai_1999_J.Biol.Chem_274_11053 |
| PubMedID: 10196188 |
| Gene_locus related to this paper: human-PLA1A |