1-Stearoyl-2-arachidonoylglycerol

General

Type : Natural, Acyl-Glycerol

Chemical_Nomenclature : (1-hydroxy-3-octadecanoyloxypropan-2-yl) (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate

Canonical SMILES : CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC

InChI : InChI=1S\/C41H72O5\/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2\/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3\/b13-11-,19-17-,24-22-,30-28-

InChIKey : NSXLMTYRMFVYNT-LGHBDAFPSA-N || NSXLMTYRMFVYNT-IUJDHQGTSA-N

Other name(s) : 1-Stearoyl-2-arachidonoyl-SN-glycerol  ||  1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate  ||  SCHEMBL1412343  ||  CHEBI:83288  ||  DAG  ||  1-STEAROYL-2-ARACHIDONOYL-GLYCEROL  ||  [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate  ||  Diacylglycerol(18:0\/20:4)  ||  SCHEMBL1009384  ||  CHEBI:75728  ||  DAG(18:0\/20:4)  ||  ZINC8860480  ||  DAG(18:0\/20:4n6)


MW : 645.02

Formula : C41H72O5

CAS_number : 65914-84-3

PubChem : 14345637,    6438587

UniChem : NSXLMTYRMFVYNT-LGHBDAFPSA-N,    NSXLMTYRMFVYNT-IUJDHQGTSA-N

Target

Structures : No structure

Families : Lipase_3

References (3)

Title : A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase alpha - van der Wel_2015_J.Lipid.Res_56_927
Author(s) : van der Wel T , Janssen FJ , Baggelaar MP , Deng H , den Dulk H , Overkleeft HS , van der Stelt M
Ref : J Lipid Res , 56 :927 , 2015
Abstract :
PubMedSearch : van der Wel_2015_J.Lipid.Res_56_927
PubMedID: 25684760

Title : Assay and inhibition of diacylglycerol lipase activity - Johnston_2012_Bioorg.Med.Chem.Lett_22_4585
Author(s) : Johnston M , Bhatt SR , Sikka S , Mercier RW , West JM , Makriyannis A , Gatley SJ , Duclos RI, Jr.
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :4585 , 2012
Abstract :
PubMedSearch : Johnston_2012_Bioorg.Med.Chem.Lett_22_4585
PubMedID: 22738638

Title : Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line - Rimmerman_2008_Br.J.Pharmacol_153_380
Author(s) : Rimmerman N , Hughes HV , Bradshaw HB , Pazos MX , Mackie K , Prieto AL , Walker JM
Ref : British Journal of Pharmacology , 153 :380 , 2008
Abstract :
PubMedSearch : Rimmerman_2008_Br.J.Pharmacol_153_380
PubMedID: 17965731