| Title : Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors - Jiang_2024_J.Med.Chem__ |
| Author(s) : Jiang M , Huizenga MCW , Mohr F , Amedi A , Bakker R , van den Berg R , Deng H , van der Wel T , van Boeckel CAA , van der Stelt M |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Jiang_2024_J.Med.Chem__ |
| PubMedID: 38988250 |
| Title : Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors - Yu_2024_Bioorg.Med.Chem_111_117844 |
| Author(s) : Yu Q , Song C , Bi L , Zhao S , Lei Q , Yang N , Chen H , Wang Y , He Y , Deng H |
| Ref : Bioorganic & Medicinal Chemistry , 111 :117844 , 2024 |
| Abstract : |
| PubMedSearch : Yu_2024_Bioorg.Med.Chem_111_117844 |
| PubMedID: 39106652 |
| Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039 |
| Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M |
| Ref : Nat Commun , 14 :8039 , 2023 |
| Abstract : |
| PubMedSearch : Jiang_2023_Nat.Commun_14_8039 |
| PubMedID: 38052772 |
| Title : Comprehensive in-silico analysis of deleterious SNPs in APOC2 and APOA5 and their differential expression in cancer and cardiovascular diseases conditions - Deng_2023_Genomics_115_110567 |
| Author(s) : Deng H , Li J , Shah AA , Ge L , Ouyang W |
| Ref : Genomics , 115 :110567 , 2023 |
| Abstract : |
| PubMedSearch : Deng_2023_Genomics_115_110567 |
| PubMedID: 36690263 |
| Title : Nanoclusterzyme for Dual Colorimetric Sensings: A Case Study on [Au(14) (Dppp)(5) I(4) ](2) - Zhao_2023_Small__e2207936 |
| Author(s) : Zhao H , You Q , Zhu W , Li J , Deng H , Li MB , Zhao Y , Wu Z |
| Ref : Small , :e2207936 , 2023 |
| Abstract : |
| PubMedSearch : Zhao_2023_Small__e2207936 |
| PubMedID: 37060229 |
| Title : GPIHBP1 autoantibody is an independent risk factor for the recurrence of hypertriglyceridemia-induced acute pancreatitis - Zhang_2022_J.Clin.Lipidol__ |
| Author(s) : Zhang G , Yang Q , Mao W , Hu Y , Pu N , Deng H , Yu X , Zhang J , Zhou J , Ye B , Li G , Li B , Ke L , Tong Z , Murakami M , Kimura T , Nakajima K , Cao W , Liu Y , Li W |
| Ref : J Clin Lipidol , : , 2022 |
| Abstract : |
| PubMedSearch : Zhang_2022_J.Clin.Lipidol__ |
| PubMedID: 36064883 |
| Title : Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling - Deng_2022_Front.Pharmacol_13_941522 |
| Author(s) : Deng H , Zhang Q , Lei Q , Yang N , Yang K , Jiang J , Yu Z |
| Ref : Front Pharmacol , 13 :941522 , 2022 |
| Abstract : |
| PubMedSearch : Deng_2022_Front.Pharmacol_13_941522 |
| PubMedID: 36105202 |
| Title : Effect of Selenium on Brain Injury in Chickens with Subacute Arsenic Poisoning - Ren_2021_Biol.Trace.Elem.Res__ |
| Author(s) : Ren Z , Deng H , Wu Q , Jia G , Wen N , Deng Y , Zhu L , Zuo Z , Deng J |
| Ref : Biol Trace Elem Res , : , 2021 |
| Abstract : |
| PubMedSearch : Ren_2021_Biol.Trace.Elem.Res__ |
| PubMedID: 33594525 |
| Title : Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders - Deng_2020_Acta.Pharm.Sin.B_10_582 |
| Author(s) : Deng H , Li W |
| Ref : Acta Pharm Sin B , 10 :582 , 2020 |
| Abstract : |
| PubMedSearch : Deng_2020_Acta.Pharm.Sin.B_10_582 |
| PubMedID: 32322464 |
| Title : Therapeutic potential of targeting alpha\/beta-Hydrolase domain-containing 6 (ABHD6) - Deng_2020_Eur.J.Med.Chem_198_112353 |
| Author(s) : Deng H , Li W |
| Ref : Eur Journal of Medicinal Chemistry , 198 :112353 , 2020 |
| Abstract : |
| PubMedSearch : Deng_2020_Eur.J.Med.Chem_198_112353 |
| PubMedID: 32371333 |
| Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
| Title : Efficacy and safety of DBPR108 monotherapy in patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled, phase II clinical trial - Wang_2020_Curr.Med.Res.Opin_36_1107 |
| Author(s) : Wang W , Yao J , Guo X , Guo Y , Yan C , Liu K , Zhang Y , Wang X , Li H , Wen Z , Li S , Xiao X , Liu W , Li Z , Zhang L , Shao S , Ye S , Qin G , Li Y , Li F , Zhang X , Li X , Peng Y , Deng H , Xu X , Zhou L , Huang Y , Cao M , Xia X , Shi M , Dou J , Yuan J |
| Ref : Curr Med Res Opin , 36 :1107 , 2020 |
| Abstract : |
| PubMedSearch : Wang_2020_Curr.Med.Res.Opin_36_1107 |
| PubMedID: 32338063 |
| Title : A novel feruloyl esterase with high rosmarinic acid hydrolysis activity from Bacillus pumilus W3 - Liang_2020_Int.J.Biol.Macromol_161_525 |
| Author(s) : Liang W , Xiong T , Wang X , Deng H , Bai Y , Fan TP , Zheng X , Cai Y |
| Ref : Int J Biol Macromol , 161 :525 , 2020 |
| Abstract : |
| PubMedSearch : Liang_2020_Int.J.Biol.Macromol_161_525 |
| PubMedID: 32531366 |
| Gene_locus related to this paper: 9baci-BpFae12 |
| Title : Characterization of a novel carboxylesterase from Bacillus velezensis SYBC H47 and its application in degradation of phthalate esters - Huang_2020_J.Biosci.Bioeng_129_588 |
| Author(s) : Huang L , Meng D , Tian Q , Yang S , Deng H , Guan Z , Cai Y , Liao X |
| Ref : J Biosci Bioeng , 129 :588 , 2020 |
| Abstract : |
| PubMedSearch : Huang_2020_J.Biosci.Bioeng_129_588 |
| PubMedID: 31761671 |
| Gene_locus related to this paper: baca2-a7z8b1 |
| Title : Expression and characterisation of feruloyl esterases from Lactobacillus fermentum JN248 and release of ferulic acid from wheat bran - Deng_2019_Int.J.Biol.Macromol_138_272 |
| Author(s) : Deng H , Jia P , Jiang J , Bai Y , Fan TP , Zheng X , Cai Y |
| Ref : Int J Biol Macromol , 138 :272 , 2019 |
| Abstract : |
| PubMedSearch : Deng_2019_Int.J.Biol.Macromol_138_272 |
| PubMedID: 31306699 |
| Title : Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification - van Rooden_2018_Nat.Protoc_13_752 |
| Author(s) : van Rooden EJ , Florea BI , Deng H , Baggelaar MP , van Esbroeck ACM , Zhou J , Overkleeft HS , van der Stelt M |
| Ref : Nat Protoc , 13 :752 , 2018 |
| Abstract : |
| PubMedSearch : van Rooden_2018_Nat.Protoc_13_752 |
| PubMedID: 29565900 |
| Title : Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain - van Rooden_2018_Front.Neurosci_12_440 |
| Author(s) : van Rooden EJ , van Esbroeck ACM , Baggelaar MP , Deng H , Florea BI , Marques ARA , Ottenhoff R , Boot RG , Overkleeft HS , Aerts J , van der Stelt M |
| Ref : Front Neurosci , 12 :440 , 2018 |
| Abstract : |
| PubMedSearch : van Rooden_2018_Front.Neurosci_12_440 |
| PubMedID: 30018533 |
| Title : Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-alpha and ABHD6 inhibitors - Deng_2017_Medchemcomm_8_982 |
| Author(s) : Deng H , van der Wel T , van den Berg R , van den Nieuwendijk A , Janssen FJ , Baggelaar MP , Overkleeft HS , van der Stelt M |
| Ref : Medchemcomm , 8 :982 , 2017 |
| Abstract : |
| PubMedSearch : Deng_2017_Medchemcomm_8_982 |
| PubMedID: 30108813 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : miR27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker - Liu_2017_Oncol.Rep_37_3554 |
| Author(s) : Liu W , Qian K , Wei X , Deng H , Zhao B , Chen Q , Zhang J , Liu H |
| Ref : Oncol Rep , 37 :3554 , 2017 |
| Abstract : |
| PubMedSearch : Liu_2017_Oncol.Rep_37_3554 |
| PubMedID: 28440497 |
| Gene_locus related to this paper: human-f172a |
| Title : Genetic analysis of the RIC3 gene in Han Chinese patients with Parkinson's disease - He_2017_Neurosci.Lett_653_351 |
| Author(s) : He D , Hu P , Deng X , Song Z , Yuan L , Yuan X , Deng H |
| Ref : Neuroscience Letters , 653 :351 , 2017 |
| Abstract : |
| PubMedSearch : He_2017_Neurosci.Lett_653_351 |
| PubMedID: 28606768 |
| Title : Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding - Deng_2017_J.Med.Chem_60_428 |
| Author(s) : Deng H , Kooijman S , van den Nieuwendijk AM , Ogasawara D , van der Wel T , van Dalen F , Baggelaar MP , Janssen FJ , van den Berg RJ , den Dulk H , Cravatt BF , Overkleeft HS , Rensen PC , van der Stelt M |
| Ref : Journal of Medicinal Chemistry , 60 :428 , 2017 |
| Abstract : |
| PubMedSearch : Deng_2017_J.Med.Chem_60_428 |
| PubMedID: 27992221 |
| Title : Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 - van Esbroeck_2017_Science_356_1084 |
| Author(s) : van Esbroeck ACM , Janssen APA , Cognetta AB, 3rd , Ogasawara D , Shpak G , van der Kroeg M , Kantae V , Baggelaar MP , de Vrij FMS , Deng H , Allara M , Fezza F , Lin Z , van der Wel T , Soethoudt M , Mock ED , den Dulk H , Baak IL , Florea BI , Hendriks G , De Petrocellis L , Overkleeft HS , Hankemeier T , De Zeeuw CI , Di Marzo V , Maccarrone M , Cravatt BF , Kushner SA , van der Stelt M |
| Ref : Science , 356 :1084 , 2017 |
| Abstract : |
| PubMedSearch : van Esbroeck_2017_Science_356_1084 |
| PubMedID: 28596366 |
| Title : Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity - Soethoudt_2017_Nat.Commun_8_13958 |
| Author(s) : Soethoudt M , Grether U , Fingerle J , Grim TW , Fezza F , De Petrocellis L , Ullmer C , Rothenhausler B , Perret C , van Gils N , Finlay D , MacDonald C , Chicca A , Gens MD , Stuart J , de Vries H , Mastrangelo N , Xia L , Alachouzos G , Baggelaar MP , Martella A , Mock ED , Deng H , Heitman LH , Connor M , Di Marzo V , Gertsch J , Lichtman AH , Maccarrone M , Pacher P , Glass M , van der Stelt M |
| Ref : Nat Commun , 8 :13958 , 2017 |
| Abstract : |
| PubMedSearch : Soethoudt_2017_Nat.Commun_8_13958 |
| PubMedID: 28045021 |
| Title : Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition - Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| Author(s) : Ogasawara D , Deng H , Viader A , Baggelaar MP , Breman A , den Dulk H , van den Nieuwendijk AM , Soethoudt M , van der Wel T , Zhou J , Overkleeft HS , Sanchez-Alavez M , Mori S , Nguyen W , Conti B , Liu X , Chen Y , Liu QS , Cravatt BF , van der Stelt M |
| Ref : Proc Natl Acad Sci U S A , 113 :26 , 2016 |
| Abstract : |
| PubMedSearch : Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| PubMedID: 26668358 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : DWARF14 is a non-canonical hormone receptor for strigolactone - Yao_2016_Nature_536_469 |
| Author(s) : Yao R , Ming Z , Yan L , Li S , Wang F , Ma S , Yu C , Yang M , Chen L , Li Y , Yan C , Miao D , Sun Z , Yan J , Sun Y , Wang L , Chu J , Fan S , He W , Deng H , Nan F , Li J , Rao Z , Lou Z , Xie D |
| Ref : Nature , 536 :469 , 2016 |
| Abstract : |
| PubMedSearch : Yao_2016_Nature_536_469 |
| PubMedID: 27479325 |
| Gene_locus related to this paper: arath-AtD14 |
| Title : The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution - Zhang_2016_Sci.Rep_6_19029 |
| Author(s) : Zhang GQ , Xu Q , Bian C , Tsai WC , Yeh CM , Liu KW , Yoshida K , Zhang LS , Chang SB , Chen F , Shi Y , Su YY , Zhang YQ , Chen LJ , Yin Y , Lin M , Huang H , Deng H , Wang ZW , Zhu SL , Zhao X , Deng C , Niu SC , Huang J , Wang M , Liu GH , Yang HJ , Xiao XJ , Hsiao YY , Wu WL , Chen YY , Mitsuda N , Ohme-Takagi M , Luo YB , Van de Peer Y , Liu ZJ |
| Ref : Sci Rep , 6 :19029 , 2016 |
| Abstract : |
| PubMedSearch : Zhang_2016_Sci.Rep_6_19029 |
| PubMedID: 26754549 |
| Gene_locus related to this paper: 9aspa-a0a2i0w093 , 9aspa-a0a2i0vyy1 , 9aspa-a0a2i0x5j6 , 9aspa-a0a2i0win6 , 9aspa-a0a2i0vg82 |
| Title : Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease - Liao_2015_Bioorg.Med.Chem.Lett_25_1541 |
| Author(s) : Liao S , Deng H , Huang S , Yang J , Wang S , Yin B , Zheng T , Zhang D , Liu J , Gao G , Ma J , Deng Z |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1541 , 2015 |
| Abstract : |
| PubMedSearch : Liao_2015_Bioorg.Med.Chem.Lett_25_1541 |
| PubMedID: 25724825 |
| Title : Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons - Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| Author(s) : Baggelaar MP , Chameau PJ , Kantae V , Hummel J , Hsu KL , Janssen F , van der Wel T , Soethoudt M , Deng H , den Dulk H , Allara M , Florea BI , Di Marzo V , Wadman WJ , Kruse CG , Overkleeft HS , Hankemeier T , Werkman TR , Cravatt BF , van der Stelt M |
| Ref : Journal of the American Chemical Society , 137 :8851 , 2015 |
| Abstract : |
| PubMedSearch : Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| PubMedID: 26083464 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3beta signaling pathway - Liang_2015_Biochem.Biophys.Res.Commun_463_70 |
| Author(s) : Liang Y , Jing Z , Deng H , Li Z , Zhuang Z , Wang S , Wang Y |
| Ref : Biochemical & Biophysical Research Communications , 463 :70 , 2015 |
| Abstract : |
| PubMedSearch : Liang_2015_Biochem.Biophys.Res.Commun_463_70 |
| PubMedID: 25986738 |
| Title : A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase alpha - van der Wel_2015_J.Lipid.Res_56_927 |
| Author(s) : van der Wel T , Janssen FJ , Baggelaar MP , Deng H , den Dulk H , Overkleeft HS , van der Stelt M |
| Ref : J Lipid Res , 56 :927 , 2015 |
| Abstract : |
| PubMedSearch : van der Wel_2015_J.Lipid.Res_56_927 |
| PubMedID: 25684760 |
| Title : Resurfaced fluorescent protein as a sensing platform for label-free detection of copper(II) ion and acetylcholinesterase activity - Lei_2015_Anal.Chem_87_1974 |
| Author(s) : Lei C , Wang Z , Nie Z , Deng H , Hu H , Huang Y , Yao S |
| Ref : Analytical Chemistry , 87 :1974 , 2015 |
| Abstract : |
| PubMedSearch : Lei_2015_Anal.Chem_87_1974 |
| PubMedID: 25560517 |
| Title : Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase alpha and alpha\/beta-Hydrolase Domain 6 - Janssen_2014_J.Med.Chem_57_6610 |
| Author(s) : Janssen FJ , Deng H , Baggelaar MP , Allara M , van der Wel T , den Dulk H , Ligresti A , van Esbroeck AC , McGuire R , Di Marzo V , Overkleeft HS , van der Stelt M |
| Ref : Journal of Medicinal Chemistry , 57 :6610 , 2014 |
| Abstract : |
| PubMedSearch : Janssen_2014_J.Med.Chem_57_6610 |
| PubMedID: 24988361 |
| Title : Probing biochemical mechanisms of action of muscarinic M3 receptor antagonists with label-free whole cell assays - Deng_2012_Anal.Chem_84_8232 |
| Author(s) : Deng H , Wang C , Su M , Fang Y |
| Ref : Analytical Chemistry , 84 :8232 , 2012 |
| Abstract : |
| PubMedSearch : Deng_2012_Anal.Chem_84_8232 |
| PubMedID: 22954104 |
| Title : Complete genome sequences of Mycobacterium tuberculosis strains CCDC5079 and CCDC5080, which belong to the Beijing family - Zhang_2011_J.Bacteriol_193_5591 |
| Author(s) : Zhang Y , Chen C , Liu J , Deng H , Pan A , Zhang L , Zhao X , Huang M , Lu B , Dong H , Du P , Chen W , Wan K |
| Ref : Journal of Bacteriology , 193 :5591 , 2011 |
| Abstract : |
| PubMedSearch : Zhang_2011_J.Bacteriol_193_5591 |
| PubMedID: 21914894 |
| Gene_locus related to this paper: myctu-cut3 , myctu-cutas1 , myctu-cutas2 , myctu-Rv0160c , myctu-Rv1069c , myctu-RV1215C , myctu-Rv2045c , myctu-RV3452 , myctu-RV3724 , myctu-Rv3802c , myctu-y0571 |
| Title : Scrapie strain infection in vitro induces changes in neuronal cells. - Rubenstein_1994_Mol.Neurobiol_8_129 |
| Author(s) : Rubenstein R , Deng H , Race R , Ju W , Scalici C , Papini M , Rubenstein A , Kascsak R , Carp R |
| Ref : Molecular Neurobiology , 8 :129 , 1994 |
| Abstract : |
| PubMedSearch : Rubenstein_1994_Mol.Neurobiol_8_129 |
| PubMedID: 7999309 |