Sigma1R
General
Ligand of Sigma1 receptor. Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds
| Inhibitor | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| CHEMBL4595876 | ACHE | Multitarget Pyridine Sigma1R Cyanide |
|
| Sigma1R-ACHE-6a | ACHE | Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil |
|
| Sigma1R-ACHE-6b | ACHE | Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil |
|