5-HT-receptor-ligand

General

Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds
Inhibitor Main targeted enzyme families Type Structure
MR33317 ACHE Multitarget 5-HT-receptor-ligand Piperidine
Cpd14-BChEin-5-HT6 BCHE Multitarget 5-HT-receptor-ligand Sulfur Compound Indole Alkyl linked bis-ligand
Cpd17-Tacrine-5-HT6 ACHE BCHE Acridine Derivative of Tacrine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand anti-Abeta-aggregation
Cpd54-BChEin-5-HT6 BCHE Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand tert-Butyloxycarbonyl tert-Butyl
Cpd70-BChEin-5-HT6 BCHE Multitarget 5-HT-receptor-ligand Indole Alkyl linked bis-ligand
Cpd27-BChEin-5-HT6 BCHE Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand
Cpd35-Rivastigmine-5-HT6 BCHE Derivative of Rivastigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine BCHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Multitarget 5-HT-receptor-ligand
6o-5-HT3 BCHE ACHE Multitarget 5-HT-receptor-ligand Derivative of Tacrine Carboxamide Alkyl linked bis-ligand
Donecopride ACHE Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
RS67333 ACHE Multitarget 5-HT-receptor-ligand Piperidine
Phenolic-deriv-Donecopride-4 ACHE Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
Phenolic-deriv-Donecopride-20 ACHE Carbamate Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
Sigma1R-ACHE-6a ACHE Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
Sigma1R-ACHE-6b ACHE Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
5-hydroxy-tryptamine ACHE BCHE Derivative of Tryptamine Indole Not A\/B H target Natural 5-HT-receptor-ligand