5-HT-receptor-ligand

General

Not an alpha\/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds

Inhibitor	Main targeted enzyme familyes	Type
Cpd14-BChEin-5-HT6	BCHE	Multitarget 5-HT-receptor-ligand Sulfur Compound Indole Alkyl linked bis-ligand
Cpd17-Tacrine-5-HT6	ACHE BCHE	Acridine Derivative of Tacrine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand anti-Abeta-aggregation
Cpd54-BChEin-5-HT6	BCHE	Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand tert-Butyloxycarbonyl tert-Butyl
Cpd70-BChEin-5-HT6	BCHE	Multitarget 5-HT-receptor-ligand Indole Alkyl linked bis-ligand
Cpd27-BChEin-5-HT6	BCHE	Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Alkyl linked bis-ligand
Cpd35-Rivastigmine-5-HT6	BCHE	Derivative of Rivastigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine	BCHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Multitarget 5-HT-receptor-ligand
6o-5-HT3	BCHE ACHE	Multitarget 5-HT-receptor-ligand Derivative of Tacrine Carboxamide Alkyl linked bis-ligand
Donecopride	ACHE	Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
RS67333	ACHE	Multitarget 5-HT-receptor-ligand Piperidine
Sigma1R-ACHE-6a	ACHE	Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
Sigma1R-ACHE-6b	ACHE	Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
5-hydroxy-tryptamine	ACHE BCHE	Derivative of Tryptamine Indole Not A\/B H target Natural 5-HT-receptor-ligand