ESTHER database
Classes
Author
Block
Chemical
Disease
Enzyme
Family
Genes Locus
Inhibitor
Interact Gene Locus
Mutation
Paper
Reactivator
Species
Structure
Substrate
Type inhibitor
Type reactivator
Type substrate
Families
Overall table
All figures of families
Tools
HMMER
BLAST
Basics on AChE
Kinetics notes
Gene Structures
Molecular forms
AChE Family
Human ACHE
ESTHER Definition
Definition
Definition biblio
What is up?
Meeting
Supplementary data
Latest Modifications
Bibliography (all years)
Acknowledgements and disclaimer
Home
Type Inhibitor
5-HT-receptor-ligand
5-HT-receptor-ligand
General
Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds
Inhibitor
Main targeted enzyme families
Type
Structure
Indol-ethyl-fluorophenethyl-triazin-triamine-Cpd50
BCHE
Multitarget
5-HT-receptor-ligand
Triazine
Indole
Flucopride
ACHE
Multitarget
5-HT-receptor-ligand
Piperidine
MR33317
ACHE
Multitarget
5-HT-receptor-ligand
Piperidine
Cpd14-BChEin-5-HT6
BCHE
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Indole
Alkyl linked bis-ligand
Cpd17-Tacrine-5-HT6
ACHE
BCHE
Acridine
Derivative of Tacrine
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Sulfonamide
Indole
Alkyl linked bis-ligand
anti-Abeta-aggregation
Cpd54-BChEin-5-HT6
BCHE
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Sulfonamide
Indole
Alkyl linked bis-ligand
tert-Butyloxycarbonyl
tert-Butyl
Cpd70-BChEin-5-HT6
BCHE
Multitarget
5-HT-receptor-ligand
Indole
Alkyl linked bis-ligand
Cpd27-BChEin-5-HT6
BCHE
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Sulfonamide
Indole
Alkyl linked bis-ligand
Cpd35-Rivastigmine-5-HT6
BCHE
Derivative of Rivastigmine
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Sulfonamide
Indole
Carbamate
Alkyl linked bis-ligand
anti-Abeta-aggregation
Idalopirdine-rivastigmine
BCHE
Drug
Pro-Drug
Carbamate
Derivative of Rivastigmine
Multitarget
5-HT-receptor-ligand
6o-5-HT3
BCHE
ACHE
Multitarget
5-HT-receptor-ligand
Derivative of Tacrine
Carboxamide
Alkyl linked bis-ligand
Donecopride
ACHE
Multitarget
5-HT-receptor-ligand
Derivative of Donepezil
Piperidine
RS67333
ACHE
Multitarget
5-HT-receptor-ligand
Piperidine
Phenolic-deriv-Donecopride-4
ACHE
Multitarget
5-HT-receptor-ligand
Derivative of Donepezil
Piperidine
Phenolic-deriv-Donecopride-20
ACHE
Carbamate
Multitarget
5-HT-receptor-ligand
Derivative of Donepezil
Piperidine
Sigma1R-ACHE-6a
ACHE
Multitarget
5-HT-receptor-ligand
Piperidine
Sigma1R
Indole
Derivative of Donepezil
Sigma1R-ACHE-6b
ACHE
Multitarget
5-HT-receptor-ligand
Piperidine
Sigma1R
Indole
Derivative of Donepezil
5-hydroxy-tryptamine
ACHE
BCHE
Derivative of Tryptamine
Indole
Not AlphaBeta Hydrolase target
Natural
5-HT-receptor-ligand
