Synergist of insecticide


Insecticide resistance is frequently linked to metabolic detoxification enzymes such as cytochrome monooxygenase (P450s), esterases, glutathione S-tranferase, and carboxylesterase. To overcome insecticide resistance synergists are added to formulations. These counteract metabolic resistance. Synergists have been used in the laboratory as tools for assessing the significance of various degradation reactions for insecticide toxicity. There are specific inhibitors for oxidative and hydrolytic degradation processes. Few of these compounds are inhibitors of alpha/beta hydrolases