Plant defoliant. Removing the leaves keeps certain pests that may be found on the leaves from damaging the cotton before it is picked. DEF inhibits esterases and glutathione S-transferases. Used as synergist of carbamates, OP and pyrethrenoids. To overcome insecticide resistance could be the formulation of insecticides with synergists that counteract metabolic resistance. Used to distinguish resistance comming from mutations in the target (ACHE) or in the detoxification enzymes (esterases).
Type : Organophosphate, Synergist of insecticide, Sulfur Compound
Chemical_Nomenclature : S,S,S-Tributyltrithiophosphate
Canonical SMILES : CCCCSP(=O)(SCCCC)SCCCC
InChI : InChI=1S\/C12H27OPS3\/c1-4-7-10-15-14(13,16-11-8-5-2)17-12-9-6-3\/h4-12H2,1-3H3
InChIKey : ZOKXUAHZSKEQSS-UHFFFAOYSA-N
Other name(s) : Tribuphos || Tributylphosphorotrithioate || S,S,S-tributylphosphorotrithioate || Folex 6EC || FOS-FALL A || DEF || De-Green || E-Z-Off D || Easy off-D
MW : 314.5
Formula : C12H27OPS3
CAS_number : 78-48-8
PubChem : 5125
UniChem : ZOKXUAHZSKEQSS-UHFFFAOYSA-N
Families : Tribufos ligand of proteins in family
ACHE
BCHE
Carb_B_Arthropoda
Carb_B_Chordata
ACPH_Peptidase_S9
Protein :
human-APEH
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Ref : PLoS Negl Trop Dis , 16 :e0010501 , 2022 |
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Title : Downregulation of carboxylesterase contributes to cyflumetofen resistance in Tetranychus cinnabarinus (Boisduval) - Wei_2019_Pest.Manag.Sci_75_2166 |
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Ref : Pest Manag Sci , 75 :2166 , 2019 |
Abstract : |
PubMedSearch : Wei_2019_Pest.Manag.Sci_75_2166 |
PubMedID: 30653811 |
Gene_locus related to this paper: tetur-t1kth5 , tetur-t1kx09 , tetur-t1ju32 , tetur-t1jth6 |
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Author(s) : Lopez-Soler N , Cervera A , Quinto V , Abellan J , Bielza P , Martinez-Pardo R , Garcera MD |
Ref : Pest Manag Sci , 67 :1549 , 2011 |
Abstract : |
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Ref : J Am Mosq Control Assoc , 23 :420 , 2007 |
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Ref : Chemical Research in Toxicology , 20 :1211 , 2007 |
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Ref : Toxicol Mech Methods , 16 :235 , 2006 |
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Title : Esterase-mediated malathion resistance in the human head louse, Pediculus capitis (Anoplura: Pediculidae) - Gao_2006_Pestic.Biochem.Physiol_85_28 |
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Ref : Pesticide Biochemistry and Physiology , 85 :28 , 2006 |
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Ref : J Am Mosq Control Assoc , 14 :397 , 1998 |
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Title : Comparative organophosphate-induced effects observed in adult and neonatal Sprague-Dawley rats during the conduct of multigeneration toxicity studies - Astroff_1998_Reprod.Toxicol_12_619 |
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Ref : Reprod Toxicol , 12 :619 , 1998 |
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PubMedID: |
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