human-NDRG2

Homo sapiens (Human) ndrg2 protein N-myc downstream-regulated gene 2 protein (syld709613 protein) ndr1-related protein 2

Comment

Q96FD3 Q96JU0 Q96FT0 Q86U46 Q86U08 probable alternative splicing. Q8TDR6 very close

Relationship

Family : Ndr_family

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Database

Sequence

Peptide

MAELQEVQIT EEKPLLPGQT PEAAKEAELA ARILLDQGQT HSVETPYGSV TFTAYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGN ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEVFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C

References (13)

Title : MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN\/AKT pathway - Zhai_2022_Bioengineered_13_83
Author(s) : Zhai Z , Mu T , Zhao L , Li Y , Zhu D , Pan Y
Ref : Bioengineered , 13 :83 , 2022
PubMedID: 34951340
Gene_locus related to this paper: human-NDRG2

Title : Roles of N-myc downstream-regulated gene 2 in the central nervous system: molecular basis and relevance to pathophysiology - Takarada-Iemata_2021_Anat.Sci.Int_96_1
Author(s) : Takarada-Iemata M
Ref : Anat Sci Int , 96 :1 , 2021
PubMedID: 33174183
Gene_locus related to this paper: human-NDRG2

Title : Abnormal social behavior and altered gene expression in mice lacking NDRG2 - Takarada-Iemata_2021_Neurosci.Lett_743_135563
Author(s) : Takarada-Iemata M , Yoshihara T , Okitani N , Iwata K , Hattori T , Ishii H , Roboon J , Nguyen DT , Fan Q , Tamatani T , Nishiuchi T , Asano M , Hori O
Ref : Neuroscience Letters , 743 :135563 , 2021
PubMedID: 33359046
Gene_locus related to this paper: human-NDRG2

Title : Elemene Emulsion Injection Administration Reduces Neuropathic Pain by Inhibiting Astrocytic NDRG2 Expression within Spinal Dorsal Horn - Ma_2021_Chin.J.Integr.Med_27_912
Author(s) : Ma LT , Bai Y , Li J , Qiao Y , Liu Y , Zheng J
Ref : Chin J Integr Med , 27 :912 , 2021
PubMedID: 33420586
Gene_locus related to this paper: human-NDRG2

Title : Astrocyte-specific NDRG2 gene: functions in the brain and neurological diseases - Li_2020_Cell.Mol.Life.Sci_77_2461
Author(s) : Li X , Wu X , Luo P , Xiong L
Ref : Cell Mol Life Sciences , 77 :2461 , 2020
PubMedID: 31834421
Gene_locus related to this paper: human-NDRG2

Title : Dp44mT, an iron chelator, suppresses growth and induces apoptosis via RORA-mediated NDRG2-IL6\/JAK2\/STAT3 signaling in glioma - Zhou_2020_Cell.Oncol.(Dordr)_43_461
Author(s) : Zhou J , Jiang Y , Zhao J , Zhang H , Fu J , Luo P , Ma Y , Zou D , Gao H , Hu J , Zhang Y , Jing Z
Ref : Cell Oncol (Dordr) , 43 :461 , 2020
PubMedID: 32207044
Gene_locus related to this paper: human-NDRG2

Title : Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor - Hwang_2011_J.Biol.Chem_286_12450
Author(s) : Hwang J , Kim Y , Kang HB , Jaroszewski L , Deacon AM , Lee H , Choi WC , Kim KJ , Kim CH , Kang BS , Lee JO , Oh TK , Kim JW , Wilson IA , Kim MH
Ref : Journal of Biological Chemistry , 286 :12450 , 2011
PubMedID: 21247902
Gene_locus related to this paper: human-NDRG2

Title : NDRG2: a novel Alzheimer's disease associated protein - Mitchelmore_2004_Neurobiol.Dis_16_48
Author(s) : Mitchelmore C , Buchmann-Moller S , Rask L , West MJ , Troncoso JC , Jensen NA
Ref : Neurobiol Dis , 16 :48 , 2004
PubMedID: 15207261
Gene_locus related to this paper: human-NDRG2

Title : Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family - Qu_2002_Mol.Cell.Biochem_229_35
Author(s) : Qu X , Zhai Y , Wei H , Zhang C , Xing G , Yu Y , He F
Ref : Molecular & Cellular Biochemistry , 229 :35 , 2002
PubMedID: 11936845
Gene_locus related to this paper: human-NDRG1 , human-NDRG2 , human-NDRG3 , human-NDRG4

Title : Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart - Zhou_2001_Genomics_73_86
Author(s) : Zhou RH , Kokame K , Tsukamoto Y , Yutani C , Kato H , Miyata T
Ref : Genomics , 73 :86 , 2001
PubMedID: 11352569
Gene_locus related to this paper: human-NDRG2 , human-NDRG3 , human-NDRG4

Title : The sequence of the human genome - Venter_2001_Science_291_1304
Author(s) : Venter JC , Adams MD , Myers EW , Li PW , Mural RJ , Sutton GG , Smith HO , Yandell M , Evans CA , Holt RA , Gocayne JD , Amanatides P , Ballew RM , Huson DH , Wortman JR , Zhang Q , Kodira CD , Zheng XH , Chen L , Skupski M , Subramanian G , Thomas PD , Zhang J , Gabor Miklos GL , Nelson C , Broder S , Clark AG , Nadeau J , McKusick VA , Zinder N , Levine AJ , Roberts RJ , Simon M , Slayman C , Hunkapiller M , Bolanos R , Delcher A , Dew I , Fasulo D , Flanigan M , Florea L , Halpern A , Hannenhalli S , Kravitz S , Levy S , Mobarry C , Reinert K , Remington K , Abu-Threideh J , Beasley E , Biddick K , Bonazzi V , Brandon R , Cargill M , Chandramouliswaran I , Charlab R , Chaturvedi K , Deng Z , Di Francesco V , Dunn P , Eilbeck K , Evangelista C , Gabrielian AE , Gan W , Ge W , Gong F , Gu Z , Guan P , Heiman TJ , Higgins ME , Ji RR , Ke Z , Ketchum KA , Lai Z , Lei Y , Li Z , Li J , Liang Y , Lin X , Lu F , Merkulov GV , Milshina N , Moore HM , Naik AK , Narayan VA , Neelam B , Nusskern D , Rusch DB , Salzberg S , Shao W , Shue B , Sun J , Wang Z , Wang A , Wang X , Wang J , Wei M , Wides R , Xiao C , Yan C , Yao A , Ye J , Zhan M , Zhang W , Zhang H , Zhao Q , Zheng L , Zhong F , Zhong W , Zhu S , Zhao S , Gilbert D , Baumhueter S , Spier G , Carter C , Cravchik A , Woodage T , Ali F , An H , Awe A , Baldwin D , Baden H , Barnstead M , Barrow I , Beeson K , Busam D , Carver A , Center A , Cheng ML , Curry L , Danaher S , Davenport L , Desilets R , Dietz S , Dodson K , Doup L , Ferriera S , Garg N , Gluecksmann A , Hart B , Haynes J , Haynes C , Heiner C , Hladun S , Hostin D , Houck J , Howland T , Ibegwam C , Johnson J , Kalush F , Kline L , Koduru S , Love A , Mann F , May D , McCawley S , McIntosh T , McMullen I , Moy M , Moy L , Murphy B , Nelson K , Pfannkoch C , Pratts E , Puri V , Qureshi H , Reardon M , Rodriguez R , Rogers YH , Romblad D , Ruhfel B , Scott R , Sitter C , Smallwood M , Stewart E , Strong R , Suh E , Thomas R , Tint NN , Tse S , Vech C , Wang G , Wetter J , Williams S , Williams M , Windsor S , Winn-Deen E , Wolfe K , Zaveri J , Zaveri K , Abril JF , Guigo R , Campbell MJ , Sjolander KV , Karlak B , Kejariwal A , Mi H , Lazareva B , Hatton T , Narechania A , Diemer K , Muruganujan A , Guo N , Sato S , Bafna V , Istrail S , Lippert R , Schwartz R , Walenz B , Yooseph S , Allen D , Basu A , Baxendale J , Blick L , Caminha M , Carnes-Stine J , Caulk P , Chiang YH , Coyne M , Dahlke C , Mays A , Dombroski M , Donnelly M , Ely D , Esparham S , Fosler C , Gire H , Glanowski S , Glasser K , Glodek A , Gorokhov M , Graham K , Gropman B , Harris M , Heil J , Henderson S , Hoover J , Jennings D , Jordan C , Jordan J , Kasha J , Kagan L , Kraft C , Levitsky A , Lewis M , Liu X , Lopez J , Ma D , Majoros W , McDaniel J , Murphy S , Newman M , Nguyen T , Nguyen N , Nodell M , Pan S , Peck J , Peterson M , Rowe W , Sanders R , Scott J , Simpson M , Smith T , Sprague A , Stockwell T , Turner R , Venter E , Wang M , Wen M , Wu D , Wu M , Xia A , Zandieh A , Zhu X
Ref : Science , 291 :1304 , 2001
PubMedID: 11181995
Gene_locus related to this paper: human-AADAC , human-ABHD1 , human-ABHD10 , human-ABHD11 , human-ACHE , human-BCHE , human-LDAH , human-ABHD18 , human-CMBL , human-ABHD17A , human-KANSL3 , human-LIPA , human-LYPLAL1 , human-NDRG2 , human-NLGN3 , human-NLGN4X , human-NLGN4Y , human-PAFAH2 , human-PREPL , human-RBBP9 , human-SPG21

Title : Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs - Wiemann_2001_Genome.Res_11_422
Author(s) : Wiemann S , Weil B , Wellenreuther R , Gassenhuber J , Glassl S , Ansorge W , Boecher M , Bloecker H , Bauersachs S , Blum H , Lauber J , Duesterhoeft A , Beyer A , Koehrer K , Strack N , Mewes H-W , Ottenwaelder B , Obermaier B , Tampe J , Heubner D , Wambutt R , Korn B , Klein M , Poustka A , Bocher M , Blocker H , Dusterhoft A , Kohrer K , Mewes HW , Ottenwalder B
Ref : Genome Res , 11 :422 , 2001
PubMedID: 11230166
Gene_locus related to this paper: human-FAM135A , human-KANSL3 , human-NDRG2 , human-NDRG4

Title : Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro - Nagase_1999_DNA.Res_6_337
Author(s) : Nagase T , Ishikawa K , Kikuno R , Hirosawa M , Nomura N , Ohara O
Ref : DNA Research , 6 :337 , 1999
PubMedID: 10574462
Gene_locus related to this paper: human-NDRG2 , human-NLGN4X