Title : Intestinal human carboxylesterase 2 (CES2) expression rescues drug metabolism and most metabolic syndrome phenotypes in global Ces2 cluster knockout mice - Wang_2024_Acta.Pharmacol.Sin__ |
Author(s) : Wang YG , Gan CP , Beukers-Korver J , Rosing H , Li WL , Wagenaar E , Lebre MC , Song JY , Pritchard C , Bin Ali R , Huijbers I , Beijnen JH , Schinkel AH |
Ref : Acta Pharmacol Sin , : , 2024 |
Abstract : |
PubMedSearch : Wang_2024_Acta.Pharmacol.Sin__ |
PubMedID: 39496863 |
Gene_locus related to this paper: human-CES2 , mouse-Ces2a , mouse-Ces2b , mouse-Ces2c , mouse-Ces2d-ps , mouse-Ces2e , mouse-Ces2f , mouse-Ces2g , mouse-Ces2h |
Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
Ref : Acta Pharm Sin B , 13 :618 , 2023 |
Abstract : |
PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
PubMedID: 36873183 |
Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
Ref : Biomed Pharmacother , 164 :114956 , 2023 |
Abstract : |
PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
PubMedID: 37267638 |
Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |
Title : P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice - Tang_2015_Mol.Pharm_12_3714 |
Author(s) : Tang SC , Kort A , Cheung KL , Rosing H , Fukami T , Durmus S , Wagenaar E , Hendrikx JJ , Nakajima M , van Vlijmen BJ , Beijnen JH , Schinkel AH |
Ref : Mol Pharm , 12 :3714 , 2015 |
Abstract : |
PubMedSearch : Tang_2015_Mol.Pharm_12_3714 |
PubMedID: 26317243 |